| Involvement of distinct G‐proteins, Gpa2 and Ras, in glucose‐and intracellular acidification‐induced cAMP signalling in the yeast Saccharomyces cerevisiae S Colombo, P Ma, L Cauwenberg, J Winderickx, M Crauwels, ... The EMBO journal, 1998 | 409 | 1998 |
| Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae S Colombo, D Ronchetti, JM Thevelein, J Winderickx, E Martegani Journal of Biological Chemistry 279 (45), 46715-46722, 2004 | 179 | 2004 |
| Nutrient-induced signal transduction through the protein kinase A pathway and its role in the control of metabolism, stress resistance, and growth in yeast JM Thevelein, L Cauwenberg, S Colombo, JH De Winde, M Donation, ... Enzyme and microbial technology 26 (9-10), 819-825, 2000 | 162 | 2000 |
| Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast JE Leadsham, K Miller, KR Ayscough, S Colombo, E Martegani, ... Journal of cell science 122 (5), 706-715, 2009 | 114 | 2009 |
| Role of guanine nucleotides in the regulation of the Ras/cAMP pathway in Saccharomyces cerevisiae S Rudoni, S Colombo, P Coccetti, E Martegani Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1538 (2-3), 181-189, 2001 | 80 | 2001 |
| Purification and characterization of a thermostable carboxypeptidase from the extreme thermophilic archaebacterium Sulfolobus solfataricus S Colombo, S D'AURIA, P Fusi, L Zecca, CA Raia, P Tortora European journal of biochemistry 206 (2), 349-357, 1992 | 62 | 1992 |
| Design, synthesis and biological evaluation of sugar‐derived Ras inhibitors F Peri, C Airoldi, S Colombo, E Martegani, AS van Neuren, M Stein, ... Chembiochem 6 (10), 1839-1848, 2005 | 61 | 2005 |
| Modeling and stochastic simulation of the Ras/cAMP/PKA pathway in the yeast Saccharomyces cerevisiae evidences a key regulatory function for intracellular … P Cazzaniga, D Pescini, D Besozzi, G Mauri, S Colombo, E Martegani Journal of biotechnology 133 (3), 377-385, 2008 | 60 | 2008 |
| A mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1K1876M, specifically affects glucose‐ and acidification‐induced cAMP signalling and not the … M Vanhalewyn, F Dumortier, G Debast, S Colombo, P Ma, J Winderickx, ... Molecular microbiology 33 (2), 363-376, 1999 | 56 | 1999 |
| Characterization of a new set of mutants deficient in fermentation-induced loss of stress resistance for use in frozen dough applications P Van Dijck, MF Gorwa, K Lemaire, A Teunissen, M Versele, S Colombo, ... International journal of food microbiology 55 (1-3), 187-192, 2000 | 51 | 2000 |
| The role of feedback control mechanisms on the establishment of oscillatory regimes in the Ras/cAMP/PKA pathway in S. cerevisiae D Besozzi, P Cazzaniga, D Pescini, G Mauri, S Colombo, E Martegani EURASIP Journal on Bioinformatics and Systems Biology 2012, 1-17, 2012 | 48 | 2012 |
| Simulation of the Ras/cAMP/PKA pathway in budding yeast highlights the establishment of stable oscillatory states D Pescini, P Cazzaniga, D Besozzi, G Mauri, L Amigoni, S Colombo, ... Biotechnology advances 30 (1), 99-107, 2012 | 41 | 2012 |
| Lack of HXK2 Induces Localization of Active Ras in Mitochondria and Triggers Apoptosis in the Yeast Saccharomyces cerevisiae L Amigoni, E Martegani, S Colombo Oxidative medicine and cellular longevity 2013 (1), 678473, 2013 | 40 | 2013 |
| A Baker's Yeast Mutant (fil 1) With a Specific, Partially Inactivating Mutation in Adenylate Cyclase Maintains a High Stress Resistance During Active Fermentation and Growth P Van Dijck, P Ma, M Versele, MF Gorwa, S Colombo, K Lemaire, D Bossi, ... Journal of molecular microbiology and biotechnology 2 (4), 521-530, 2000 | 39 | 2000 |
| Live-cell imaging of endogenous Ras-GTP shows predominant Ras activation at the plasma membrane and in the nucleus in Saccharomyces cerevisiae S Broggi, E Martegani, S Colombo The international journal of biochemistry & cell biology 45 (2), 384-394, 2013 | 38 | 2013 |
| Design, Synthesis, and Biological Evaluation of Levoglucosenone‐Derived Ras Activation Inhibitors C Müller, MA Gomez‐Zurita Frau, D Ballinari, S Colombo, A Bitto, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (4), 524-528, 2009 | 38 | 2009 |
| Molecular cloning, nucleotide sequence, and expression of a carboxypeptidase-encoding gene from the archaebacterium Sulfolobus solfataricus S Colombo, G Toietta, L Zecca, M Vanoni, P Tortora Journal of bacteriology 177 (19), 5561-5566, 1995 | 37 | 1995 |
| Structural features responsible for kinetic thermal stability of a carboxypeptidase from the archaebacterium Sulfolobus solfataricus A Villa, L Zecca, P Fusi, S Colombo, G Tedeschi, P Tortora Biochemical Journal 295 (3), 827-831, 1993 | 34 | 1993 |
| Characterization and properties of dominant-negative mutants of the Ras-specific guanine nucleotide exchange factor CDC25Mm M Vanoni, R Bertini, E Sacco, L Fontanella, M Rieppi, S Colombo, ... Journal of Biological Chemistry 274 (51), 36656-36662, 1999 | 31 | 1999 |
| Glucose-derived Ras pathway inhibitors: evidence of Ras-ligand binding and Ras-GEF (Cdc25) interaction inhibition C Airoldi, A Palmioli, A D'Urzo, S Colombo, M Vanoni, E Martegani, F Peri ChemBioChem 8 (12), 1376-1379, 2007 | 27 | 2007 |