| Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes R Karki, BR Sharma, S Tuladhar, EP Williams, L Zalduondo, P Samir, ... Cell 184 (1), 149-168. e17, 2021 | 1397 | 2021 |
| Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome Y Chen, W Liang, S Yang, N Wu, H Gao, J Sheng, H Yao, J Wo, Q Fang, ... The Lancet 381 (9881), 1916-1925, 2013 | 1128 | 2013 |
| TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines M Zheng, R Karki, EP Williams, D Yang, E Fitzpatrick, P Vogel, ... Nature immunology 22 (7), 829-838, 2021 | 551 | 2021 |
| Caspase-6 is a key regulator of innate immunity, inflammasome activation, and host defense M Zheng, R Karki, P Vogel, TD Kanneganti Cell 181 (3), 674-687. e13, 2020 | 387 | 2020 |
| Identification of the PANoptosome: a molecular platform triggering pyroptosis, apoptosis, and necroptosis (PANoptosis) S Christgen, M Zheng, S Kesavardhana, R Karki, RKS Malireddi, ... Frontiers in cellular and infection microbiology 10, 237, 2020 | 375 | 2020 |
| The regulation of the ZBP1‐NLRP3 inflammasome and its implications in pyroptosis, apoptosis, and necroptosis (PANoptosis) M Zheng, TD Kanneganti Immunological reviews 297 (1), 26-38, 2020 | 350 | 2020 |
| ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis R Karki, B Sundaram, BR Sharma, SJ Lee, RKS Malireddi, LN Nguyen, ... Cell reports 37 (3), 2021 | 255 | 2021 |
| Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection M Zheng, EP Williams, RKS Malireddi, R Karki, B Banoth, A Burton, ... Journal of Biological Chemistry 295 (41), 14040-14052, 2020 | 190 | 2020 |
| The K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replication W Song, P Wang, BWY Mok, SY Lau, X Huang, WL Wu, M Zheng, X Wen, ... Nature communications 5 (1), 5509, 2014 | 162 | 2014 |
| IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection T Kuriakose, M Zheng, G Neale, TD Kanneganti Journal of Immunology 200, 1489-1495, 2018 | 123 | 2018 |
| The NS1 protein of influenza A virus interacts with cellular processing bodies and stress granules through RNA-associated protein 55 (RAP55) during virus infection BWY Mok, W Song, P Wang, H Tai, Y Chen, M Zheng, X Wen, SY Lau, ... Journal of virology 86 (23), 12695-12707, 2012 | 81 | 2012 |
| Gasdermin D promotes AIM2 inflammasome activation and is required for host protection against Francisella novicida Q Zhu, M Zheng, A Balakrishnan, R Karki, TD Kanneganti The Journal of Immunology 201 (12), 3662-3668, 2018 | 74 | 2018 |
| An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells X Huang, M Zheng, P Wang, BWY Mok, S Liu, SY Lau, P Chen, YC Liu, ... Nature communications 8 (1), 1-15, 2017 | 64 | 2017 |
| NF90 exerts antiviral activity through regulation of PKR phosphorylation and stress granules in infected cells X Wen, X Huang, BWY Mok, Y Chen, M Zheng, SY Lau, P Wang, W Song, ... The Journal of Immunology 192 (8), 3753-3764, 2014 | 59 | 2014 |
| Generation of DelNS1 influenza viruses: a strategy for optimizing live attenuated influenza vaccines P Wang, M Zheng, SY Lau, P Chen, BWY Mok, S Liu, H Liu, X Huang, ... MBio 10 (5), 10.1128/mbio. 02180-19, 2019 | 57 | 2019 |
| DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response S Kesavardhana, P Samir, M Zheng, RKS Malireddi, R Karki, BR Sharma, ... Journal of Biological Chemistry 296, 2021 | 46 | 2021 |
| COVID-19 cytokines and the hyperactive immune response: Synergism of TNF-α and IFN-γ in triggering inflammation, tissue damage, and death R Karki, BR Sharma, S Tuladhar, EP Williams, L Zalduondo, P Samir, ... BioRxiv, 2020.10. 29.361048, 2020 | 38 | 2020 |
| Newly identified function of caspase-6 in ZBP1-mediated innate immune responses, NLRP3 inflammasome activation, PANoptosis, and host defense M Zheng, TD Kanneganti Journal of cellular immunology 2 (6), 341, 2020 | 28 | 2020 |
| Mammalian cells use the autophagy process to restrict avian influenza virus replication S Liu, BWY Mok, S Deng, H Liu, P Wang, W Song, P Chen, X Huang, ... Cell reports 35 (10), 2021 | 24 | 2021 |
| Cutting edge: caspase-8 is a linchpin in caspase-3 and gasdermin D activation to control cell death, cytokine release, and host defense during influenza A virus infection Y Wang, R Karki, M Zheng, B Kancharana, SJ Lee, S Kesavardhana, ... The Journal of Immunology 207 (10), 2411-2416, 2021 | 22 | 2021 |
Thirumala-Devi KannegantiSt. Jude Children's Research HospitalVerificeret mail på stjude.org