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Brent Ryckman
Brent Ryckman
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Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion
BJ Ryckman, MA Jarvis, DD Drummond, JA Nelson, DC Johnson
Journal of virology 80 (2), 710-722, 2006
4772006
Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells
BJ Ryckman, BL Rainish, MC Chase, JA Borton, JA Nelson, MA Jarvis, ...
Journal of virology 82 (1), 60-70, 2008
4622008
Ultrastructural Localization of the Herpes Simplex Virus Type 1 UL31, UL34, and US3 Proteins Suggests Specific Roles in Primary Envelopment and Egress of …
AE Reynolds, EG Wills, RJ Roller, BJ Ryckman, JD Baines
Journal of virology 76 (17), 8939-8952, 2002
4162002
UL31 and UL34 Proteins of Herpes Simplex Virus Type 1 Form a Complex That Accumulates at the Nuclear Rim and Is Required for Envelopment of Nucleocapsids
AE Reynolds, BJ Ryckman, JD Baines, Y Zhou, L Liang, RJ Roller
Journal of virology 75 (18), 8803-8817, 2001
3982001
Human cytomegalovirus gH/gL/gO promotes the fusion step of entry into all cell types, whereas gH/gL/UL128-131 broadens virus tropism through a distinct mechanism
M Zhou, JM Lanchy, BJ Ryckman
Journal of virology 89 (17), 8999-9009, 2015
2252015
HCMV gH/gL/UL128–131 interferes with virus entry into epithelial cells: evidence for cell type-specific receptors
BJ Ryckman, MC Chase, DC Johnson
Proceedings of the National Academy of Sciences 105 (37), 14118-14123, 2008
2182008
Herpes simplex virus type 1 primary envelopment: UL34 protein modification and the US3-UL34 catalytic relationship
BJ Ryckman, RJ Roller
Journal of virology 78 (1), 399-412, 2004
2132004
Human Cytomegalovirus Glycoproteins gB and gH/gL Mediate Epithelial Cell-Cell Fusion When Expressed either in cis or in trans
AL Vanarsdall, BJ Ryckman, MC Chase, DC Johnson
Journal of virology 82 (23), 11837-11850, 2008
1952008
The HSV-1 Us3 protein kinase is sufficient to block apoptosis induced by overexpression of a variety of Bcl-2 family members
PD Ogg, PJ McDonell, BJ Ryckman, CM Knudson, RJ Roller
Virology 319 (2), 212-224, 2004
1492004
Human Cytomegalovirus (HCMV) Glycoprotein gB Promotes Virus Entry In Trans Acting as the Viral Fusion Protein Rather than as a Receptor-Binding Protein
PT Wille, TW Wisner, B Ryckman, DC Johnson
MBio 4 (3), 10.1128/mbio. 00332-13, 2013
1302013
Comparative analysis of gO isoforms reveals that strains of human cytomegalovirus differ in the ratio of gH/gL/gO and gH/gL/UL128-131 in the virion envelope
M Zhou, Q Yu, A Wechsler, BJ Ryckman
Journal of virology 87 (17), 9680-9690, 2013
1292013
A viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism
G Li, CC Nguyen, BJ Ryckman, WJ Britt, JP Kamil
Proceedings of the National Academy of Sciences 112 (14), 4471-4476, 2015
1152015
Human cytomegalovirus TR strain glycoprotein O acts as a chaperone promoting gH/gL incorporation into virions but is not present in virions
BJ Ryckman, MC Chase, DC Johnson
Journal of virology 84 (5), 2597-2609, 2010
842010
Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells
FM Saccoccio, AL Sauer, X Cui, AE Armstrong, ELSE Habib, DC Johnson, ...
Vaccine 29 (15), 2705-2711, 2011
682011
Expression levels of glycoprotein O (gO) vary between strains of human cytomegalovirus, influencing the assembly of gH/gL complexes and virion infectivity
L Zhang, M Zhou, R Stanton, J Kamil, BJ Ryckman
Journal of virology 92 (15), 10.1128/jvi. 00606-18, 2018
402018
Virus entry by endocytosis
AV Nicola, HC Aguilar, J Mercer, B Ryckman, CM Wiethoff
Advances in virology 2013, 469538, 2013
392013
Polymorphisms in human cytomegalovirus glycoprotein O (gO) exert epistatic influences on cell-free and cell-to-cell spread and antibody neutralization on gH epitopes
LZ Day, C Stegmann, EP Schultz, JM Lanchy, Q Yu, BJ Ryckman
Journal of virology 94 (8), 10.1128/jvi. 02051-19, 2020
352020
Scanning mutagenesis of human cytomegalovirus glycoprotein gH/gL
EP Schultz, JM Lanchy, EE Ellerbeck, BJ Ryckman
Journal of Virology 90 (5), 2294-2305, 2016
302016
Specialization for cell-free or cell-to-cell spread of BAC-cloned human cytomegalovirus strains is determined by factors beyond the UL128-131 and RL13 loci
EP Schultz, JM Lanchy, LZ Day, Q Yu, C Peterson, J Preece, BJ Ryckman
Journal of Virology 94 (13), 10.1128/jvi. 00034-20, 2020
272020
The human cytomegalovirus protein UL116 interacts with the viral endoplasmic-reticulum-resident glycoprotein UL148 and promotes the incorporation of gH/gL complexes into virions
MNA Siddiquey, EP Schultz, Q Yu, D Amendola, G Vezzani, D Yu, ...
Journal of Virology 95 (15), 10.1128/jvi. 02207-20, 2021
132021
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