| FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation JJ Hu, X Liu, S Xia, Z Zhang, Y Zhang, J Zhao, J Ruan, X Luo, X Lou, ... Nature immunology 21 (7), 736-745, 2020 | 810 | 2020 |
| HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation VG Magupalli, R Negro, Y Tian, AV Hauenstein, G Di Caprio, W Skillern, ... Science 369 (6510), eaas8995, 2020 | 308 | 2020 |
| Fluorescent probe HKSOX-1 for imaging and detection of endogenous superoxide in live cells and in vivo JJ Hu, NK Wong, S Ye, X Chen, MY Lu, AQ Zhao, Y Guo, ACH Ma, ... Journal of the American Chemical Society 137 (21), 6837-6843, 2015 | 269 | 2015 |
| Molecular imaging of peroxynitrite with HKGreen-4 in live cells and tissues T Peng, NK Wong, X Chen, YK Chan, DHH Ho, Z Sun, JJ Hu, J Shen, ... Journal of the American Chemical Society 136 (33), 11728-11734, 2014 | 266 | 2014 |
| HKOCl-2 series of green BODIPY-based fluorescent probes for hypochlorous acid detection and imaging in live cells JJ Hu, NK Wong, Q Gu, X Bai, S Ye, D Yang Organic letters 16 (13), 3544-3547, 2014 | 192 | 2014 |
| HKOCl-3: a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay JJ Hu, NK Wong, MY Lu, X Chen, S Ye, AQ Zhao, P Gao, RYT Kao, ... Chemical science 7 (3), 2094-2099, 2016 | 149 | 2016 |
| Chain Collapse and Revival Thermodynamics of Poly(N-isopropylacrylamide) Hydrogel S Sun, J Hu, H Tang, P Wu The Journal of Physical Chemistry B 114 (30), 9761-9770, 2010 | 129 | 2010 |
| The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells S Sen Santara, DJ Lee, Â Crespo, JJ Hu, C Walker, X Ma, Y Zhang, ... Nature 616 (7956), 348-356, 2023 | 98 | 2023 |
| Small-molecule-based fluorescent sensors for selective detection of reactive oxygen species in biological systems X Bai, KKH Ng, JJ Hu, S Ye, D Yang Annual Review of Biochemistry 88 (1), 605-633, 2019 | 91 | 2019 |
| Tandem Payne/Dakin reaction: a new strategy for hydrogen peroxide detection and molecular imaging S Ye, JJ Hu, D Yang Angewandte Chemie 130 (32), 10330-10334, 2018 | 77 | 2018 |
| Fluorescent probes for in vitro and in vivo quantification of hydrogen peroxide S Ye, JJ Hu, QA Zhao, D Yang Chemical Science 11 (44), 11989-11997, 2020 | 59 | 2020 |
| Spectral interpretation of thermally irreversible recovery of poly (N-isopropylacrylamide-co-acrylic acid) hydrogel S Sun, J Hu, H Tang, P Wu Physical Chemistry Chemical Physics 13 (11), 5061-5067, 2011 | 55 | 2011 |
| Fluorescent probes for HOCl imaging JJ Hu, S Ye, D Yang Israel Journal of Chemistry 57 (3-4), 251-258, 2017 | 42 | 2017 |
| SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage KF Meza-Sosa, R Miao, F Navarro, Z Zhang, Y Zhang, JJ Hu, ... Molecular cell 82 (4), 785-802. e10, 2022 | 36 | 2022 |
| Identification of pyroptosis inhibitors that target a reactive cysteine in gasdermin D JJ Hu, X Liu, J Zhao, S Xia, J Ruan, X Luo, J Kim, J Lieberman, H Wu BioRxiv, 365908, 2018 | 34 | 2018 |
| HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science. 369: eaas8995 VG Magupalli, R Negro, Y Tian, AV Hauenstein, G Di Caprio, W Skillern, ... | 13 | 2020 |
| Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity P Fontana, G Du, Y Zhang, H Zhang, SM Vora, JJ Hu, M Shi, AB Tufan, ... Cell 187 (22), 6165-6181. e22, 2024 | 12 | 2024 |
| Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical D Yang, J Hu, NK Wong, X Bai US Patent 10,684,294, 2020 | 4 | 2020 |
| The NK receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells SS Santara, Â Crespo, DJ Lee, JJ Hu, Y Zhang, S Chowdhury, ... bioRxiv, 2021.10. 31.466654, 2021 | 2 | 2021 |
| Bistrifilate-based fluorogenic probes for detection of superoxide anion radical D Yang, NK Wong, J Hu US Patent 11,585,819, 2023 | 1 | 2023 |
Hao WuAsa and Patricia Springer Professor, Boston Children's Hospital and Harvard Medical SchoolVerificeret mail på crystal.harvard.edu