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Youwen Zhuang(庄友文)
Youwen Zhuang(庄友文)
School of Medicine, Shanghai Jiao Tong University
Verificeret mail på sjtu.edu.cn
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Citeret af
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Cryo-EM structure of the human cannabinoid receptor CB2-Gi signaling complex
C Xing, Y Zhuang, TH Xu, Z Feng, XE Zhou, M Chen, L Wang, X Meng, ...
Cell 180 (4), 645-654. e13, 2020
2452020
Structural insights into the human D1 and D2 dopamine receptor signaling complexes
Y Zhuang, P Xu, C Mao, L Wang, B Krumm, XE Zhou, S Huang, H Liu, ...
Cell 184 (4), 931-942. e18, 2021
2062021
Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy
J Duan, D Shen, XE Zhou, P Bi, Q Liu, Y Tan, Y Zhuang, H Zhang, P Xu, ...
Nature communications 11 (1), 4121, 2020
1712020
Molecular recognition of morphine and fentanyl by the human μ-opioid receptor
Y Zhuang, Y Wang, B He, X He, XE Zhou, S Guo, Q Rao, J Yang, J Liu, ...
Cell 185 (23), 4361-4375. e19, 2022
1592022
Structures of the entire human opioid receptor family
Y Wang, Y Zhuang, JF DiBerto, XE Zhou, GP Schmitz, Q Yuan, MK Jain, ...
Cell 186 (2), 413-427. e17, 2023
1062023
Structure of formylpeptide receptor 2-G i complex reveals insights into ligand recognition and signaling
Y Zhuang, H Liu, XE Zhou, RK Verma, PW de Waal, W Jang, TH Xu, ...
Nature communications 11 (1), 1-12, 2020
1062020
Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor
Q Liu, D Yang, Y Zhuang, TI Croll, X Cai, A Dai, X He, J Duan, W Yin, ...
Nature chemical biology 17 (12), 1238-1244, 2021
802021
Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor
Y Zhuang, B Krumm, H Zhang, XE Zhou, Y Wang, XP Huang, Y Liu, ...
Cell research 31 (5), 593-596, 2021
722021
Structure of the PRC2 complex and application to drug discovery
Y Shi, X Wang, Y Zhuang, Y Jiang, K Melcher, HE Xu
Acta Pharmacologica Sinica 38 (7), 963-976, 2017
702017
Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor
Y Wang, S Guo, Y Zhuang, Y Yun, P Xu, X He, J Guo, W Yin, HE Xu, X Xie, ...
Nature communications 12, 2021
642021
Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2
Y Zhuang, L Wang, J Guo, D Sun, Y Wang, W Liu, HE Xu, C Zhang
Nature communications 13 (1), 1054, 2022
562022
Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins
Y Wang, W Liu, Y Xu, X He, Q Yuan, P Luo, W Fan, J Zhu, X Zhang, ...
Nature Chemical Biology 19 (11), 1351-1360, 2023
282023
Development of “plug and play” fiducial marks for structural studies of GPCR signaling complexes by single-particle cryo-EM
P Dutka, S Mukherjee, X Gao, Y Kang, PW de Waal, L Wang, Y Zhuang, ...
Structure 27 (12), 1862-1874. e7, 2019
232019
Structural genomics of the human dopamine receptor system
P Xu, S Huang, BE Krumm, Y Zhuang, C Mao, Y Zhang, Y Wang, ...
Cell Research 33 (8), 604-616, 2023
202023
C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels
Y Shi, H Ma, Y Zhuang, X Wang, Y Jiang, HE Xu
Acta Pharmacologica Sinica 40 (11), 1457-1465, 2019
112019
Structural basis of psychedelic LSD recognition at dopamine D1 receptor
L Fan, Y Zhuang, H Wu, H Li, Y Xu, Y Wang, L He, S Wang, Z Chen, ...
Neuron 112 (19), 3295-3310. e8, 2024
12024
Molecular basis for the activation of PAF receptor by PAF
W Fan, Y Xu, X He, P Luo, J Zhu, J Li, R Wang, Q Yuan, K Wu, W Hu, ...
Cell Reports 43 (7), 2024
12024
Structural basis for ligand recognition and G protein-coupling promiscuity of the cholecystokinin A receptor
Q Liu, D Yang, Y Zhuang, TI Croll, X Cai, A Dai, X He, J Duan, W Yin, ...
bioRxiv, 2021.05. 09.443337, 2021
12021
Structural insights into the agonist activity of the nonpeptide modulator JR14a on C3aR
P Luo, W Xin, S Guo, X Li, Q Zhang, Y Xu, X He, Y Wang, W Fan, Q Yuan, ...
Cell Discovery 11 (1), 7, 2025
2025
Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
Y Wang, Y Xu, Y Wang, J Zhang, L Chen, X He, W Fan, K Wu, W Hu, ...
Proceedings of the National Academy of Sciences 121 (41), e2400298121, 2024
2024
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