Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 D Niu, HJ Wei, L Lin, H George, T Wang, IH Lee, HY Zhao, Y Wang, Y Kan, ... Science 357 (6357), 1303-1307, 2017 | 830 | 2017 |
Genome-wide inactivation of porcine endogenous retroviruses (PERVs) L Yang, M Güell, D Niu, H George, E Lesha, D Grishin, J Aach, E Shrock, ... Science 350 (6264), 1101-1104, 2015 | 704 | 2015 |
Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity E Shrock, E Fujimura, T Kula, RT Timms, IH Lee, Y Leng, ML Robinson, ... Science 370 (6520), eabd4250, 2020 | 650 | 2020 |
Design, synthesis, and testing toward a 57-codon genome N Ostrov, M Landon, M Guell, G Kuznetsov, J Teramoto, N Cervantes, ... Science 353 (6301), 819-822, 2016 | 376 | 2016 |
Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases L Lin, Y Liu, F Xu, J Huang, TF Daugaard, TS Petersen, B Hansen, L Ye, ... Gigascience 7 (3), giy011, 2018 | 80 | 2018 |
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity F Borriello, V Poli, E Shrock, R Spreafico, X Liu, N Pishesha, C Carpenet, ... Cell 185 (4), 614-629. e21, 2022 | 77 | 2022 |
CRISPR in animals and animal models E Shrock, M Güell Progress in molecular biology and translational science 152, 95-114, 2017 | 67 | 2017 |
Atomically accurate de novo design of single-domain antibodies NR Bennett, JL Watson, RJ Ragotte, AJ Borst, DL See, C Weidle, ... biorxiv, 2024 | 58 | 2024 |
Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses EL Shrock, RT Timms, T Kula, EL Mena, AP West Jr, R Guo, IH Lee, ... Science 380 (6640), eadc9498, 2023 | 50 | 2023 |
High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy G Chen, EL Shrock, MZ Li, JM Spergel, KC Nadeau, JA Pongracic, ... Cell Reports Medicine 2 (10), 2021 | 44 | 2021 |
VirScan: high-throughput profiling of antiviral antibody epitopes EL Shrock, CL Shrock, SJ Elledge Bio-protocol 12 (13), e4464-e4464, 2022 | 21 | 2022 |
CRISPR-based peptide library display and programmable microarray self-assembly for rapid quantitative protein binding assays KW Barber, E Shrock, SJ Elledge Molecular cell 81 (17), 3650-3658. e5, 2021 | 14 | 2021 |
CasPlay provides a gRNA-barcoded CRISPR-based display platform for antibody repertoire profiling KW Barber, E Shrock, SJ Elledge Cell Reports Methods 2 (10), 2022 | 1 | 2022 |
Severe acute respiratory syndrome coronavirus 2 (sars cov-2) peptide epitopes SJ Elledge, E Shrock, E Fujimura | | 2022 |