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Valur Emilsson
Valur Emilsson
Director Systems Biology
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Genetic studies of body mass index yield new insights for obesity biology
AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ...
Nature 518 (7538), 197-206, 2015
49682015
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
SFA Grant, G Thorleifsson, I Reynisdottir, R Benediktsson, A Manolescu, ...
Nature genetics 38 (3), 320-323, 2006
29012006
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
JJ Lee, R Wedow, A Okbay, E Kong, O Maghzian, M Zacher, ...
Nature genetics 50 (8), 1112-1121, 2018
24102018
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, ...
Nature 478 (7367), 103-109, 2011
23612011
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC ...
Nature genetics 44 (9), 981-990, 2012
22402012
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease
B Zhang, C Gaiteri, LG Bodea, Z Wang, J McElwee, AA Podtelezhnikov, ...
Cell 153 (3), 707-720, 2013
18442013
New genetic loci link adipose and insulin biology to body fat distribution
D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ...
Nature 518 (7538), 187-196, 2015
17222015
Genetics of gene expression and its effect on disease
V Emilsson, G Thorleifsson, B Zhang, AS Leonardson, F Zink, J Zhu, ...
Nature 452 (7186), 423-428, 2008
16202008
Genome-wide association study identifies 74 loci associated with educational attainment
A Okbay, JP Beauchamp, MA Fontana, JJ Lee, TH Pers, CA Rietveld, ...
Nature 533 (7604), 539-542, 2016
14592016
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
V Steinthorsdottir, G Thorleifsson, I Reynisdottir, R Benediktsson, ...
Nature genetics 39 (6), 770-775, 2007
12732007
Variations in DNA elucidate molecular networks that cause disease
Y Chen, J Zhu, PY Lum, X Yang, S Pinto, DJ MacNeil, C Zhang, J Lamb, ...
Nature 452 (7186), 429-435, 2008
10842008
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Nature genetics 46 (3), 234-244, 2014
10762014
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
9982017
Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
V Emilsson, YL Liu, MA Cawthorne, NM Morton, M Davenport
Diabetes 46 (2), 313-316, 1997
8161997
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ...
Nature genetics 51 (2), 245-257, 2019
7102019
Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
A Helgason, S Pálsson, G Thorleifsson, SFA Grant, V Emilsson, ...
Nature genetics 39 (2), 218-225, 2007
6582007
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
CE Elks, JRB Perry, P Sulem, DI Chasman, N Franceschini, C He, ...
Nature genetics 42 (12), 1077-1085, 2010
6102010
Co-regulatory networks of human serum proteins link genetics to disease
V Emilsson, M Ilkov, JR Lamb, N Finkel, EF Gudmundsson, R Pitts, ...
Science 361 (6404), 769-773, 2018
5352018
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
A Okbay, Y Wu, N Wang, H Jayashankar, M Bennett, SM Nehzati, ...
Nature genetics 54 (4), 437-449, 2022
5312022
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
C Pattaro, A Teumer, M Gorski, AY Chu, M Li, V Mijatovic, M Garnaas, ...
Nature communications 7 (1), 10023, 2016
5262016
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