| Nesprin-1α-dependent microtubule nucleation from the nuclear envelope via Akap450 is necessary for nuclear positioning in muscle cells P Gimpel, YL Lee, RM Sobota, A Calvi, V Koullourou, R Patel, ... Current Biology 27 (19), 2999-3009. e9, 2017 | 143 | 2017 |
| STED microscopy with optimized labeling density reveals 9-fold arrangement of a centriole protein L Lau, YL Lee, SJ Sahl, T Stearns, WE Moerner Biophysical journal 102 (12), 2926-2935, 2012 | 127 | 2012 |
| LINC complexes and nuclear positioning YL Lee, B Burke Seminars in cell & developmental biology 82, 67-76, 2018 | 104 | 2018 |
| Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole–cilium interface and facilitates proper cilium formation and function YL Lee, J Santé, CJ Comerci, B Cyge, LF Menezes, FQ Li, GG Germino, ... Molecular biology of the cell 25 (19), 2919-2933, 2014 | 67 | 2014 |
| Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy RJ Chai, H Werner, PY Li, YL Lee, KT Nyein, I Solovei, TDA Luu, ... Nature Communications 12 (1), 4722, 2021 | 63 | 2021 |
| Observing planar cell polarity in multiciliated mouse airway epithelial cells EK Vladar, YL Lee, T Stearns, JD Axelrod Methods in cell biology 127, 37-54, 2015 | 35 | 2015 |
| Nesprin-1 LINC complexes recruit microtubule cytoskeleton proteins and drive pathology in Lmna-mutant striated muscle EL Leong, NT Khaing, B Cadot, WL Hong, S Kozlov, H Werner, ... Human Molecular Genetics 32 (2), 177-191, 2023 | 23 | 2023 |
| STED super-resolution microscopy in Drosophila tissue and in mammalian cells L Lau, YL Lee, M Matis, J Axelrod, T Stearns, WE Moerner Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical …, 2011 | 14 | 2011 |
| Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity CY Tan, PS Chan, H Tan, SW Tan, CJM Lee, JW Wang, S Ye, H Werner, ... Journal of Translational Medicine 21 (1), 690, 2023 | 7 | 2023 |
| Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy. Nat Commun 12 (1) RJ Chai, H Werner, PY Li, YL Lee, KT Nyein, I Solovei This study demonstrated that mutating or ablating the LINC complex increases …, 2021 | 6 | 2021 |
| Subcellular force imbalance in actin bundles induces nuclear repositioning and durotaxis M Jun, YL Lee, T Zhou, M Maric, B Burke, S Park, BC Low, KH Chiam ACS Applied Materials & Interfaces 15 (37), 43387-43402, 2023 | 2 | 2023 |
| AAV gene therapy to treat underlying cardiac biomechanical defects in lmna dilated cardiomyopathy improves lifespan and preserves ejection fraction in Lmna DCM mouse model H Werner, ES Gan, CY Loh, NT Khaing, J Zhang, M Ong, B Burke, YC Tan, ... Circulation 146 (Suppl_1), A13927-A13927, 2022 | 1 | 2022 |
| AAV-Mediated LINC Complex Uncoupling Ameliorates Pathology in a Mouse Model of LMNA Dilated Cardiomyopathy H Werner, ES Gan, C Loh, J Ng, NT Khaing, J Zhang, M Ong, J Lee, ... Circulation 148 (Suppl_1), A12498-A12498, 2023 | | 2023 |
| Treatment/prevention of disease by linc complex inhibition CL Stewart, R SINGARAJA, B Burke, YL Lee, YC Tan US Patent App. 17/627,107, 2022 | | 2022 |
| AAV Gene Therapy Using a Genetic Suppressor Treats LMNA Dilated Cardiomyopathy in a Lmna Mouse Model Following a Decline in Ejection Fraction H Werner, YJ Loh, NT Khaing, J Zhang, M Ong, B Burke, YC Tan, ... MOLECULAR THERAPY 30 (4), 14-14, 2022 | | 2022 |
Brian BurkeASRL, SingaporeVerificeret mail på asrl.a-star.edu.sg