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Laurent POULAIN
Laurent POULAIN
Directeur de Recherche CLCC F. Baclesse, Inserm U1086, Université de Caen Normandie
Verificeret mail på baclesse.unicancer.fr
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Resistance of colon cancer cells to long‐term 5‐fluorouracil exposure is correlated to the relative level of Bcl‐2 and Bcl‐XL in addition to Bax and p53 status
S Violette, L Poulain, E Dussaulx, D Pepin, AM Faussat, J Chambaz, ...
International journal of cancer 98 (4), 498-504, 2002
3052002
Understanding the central role of citrate in the metabolism of cancer cells
P Icard, L Poulain, H Lincet
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1825 (1), 111-116, 2012
2142012
Myelodysplastic syndrome and acute myeloid leukaemia in patients treated with PARP inhibitors: a safety meta-analysis of randomised controlled trials and a retrospective study …
PM Morice, A Leary, C Dolladille, B Chrétien, L Poulain, ...
The Lancet Haematology 8 (2), e122-e134, 2021
2072021
Effect of 2-deoxy-D-glucose on various malignant cell lines in vitro
XD Zhang, E Deslandes, M Villedieu, L Poulain, M Duval, P Gauduchon, ...
Anticancer research 26 (5A), 3561-3566, 2006
1882006
Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering
E Duval, C Baugé, R Andriamanalijaona, H Bénateau, S Leclercq, ...
Biomaterials 33 (26), 6042-6051, 2012
1392012
Bcl‐XL and MCL‐1 constitute pertinent targets in ovarian carcinoma and their concomitant inhibition is sufficient to induce apoptosis
E Brotin, M Meryet‐Figuière, K Simonin, RE Duval, M Villedieu, ...
International journal of cancer 126 (4), 885-895, 2010
1332010
The p21cip1/waf1 cyclin-dependent kinase inhibitor enhances the cytotoxic effect of cisplatin in human ovarian carcinoma cells
H Lincet, L Poulain, JS Remy, E Deslandes, F Duigou, P Gauduchon, ...
Cancer letters 161 (1), 17-26, 2000
1282000
miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation
C Denoyelle, B Lambert, M Meryet-Figuiere, N Vigneron, E Brotin, ...
Cell death & disease 5 (10), e1445-e1445, 2014
1112014
Effect of citrate on malignant pleural mesothelioma cells: a synergistic effect with cisplatin
X Zhang, E Varin, S Allouche, Y Lu, L Poulain, P Icard
Anticancer Research 29 (4), 1249-1254, 2009
1002009
Citrate induces apoptotic cell death: a promising way to treat gastric carcinoma?
Y Lu, X Zhang, H Zhang, J Lan, G Huang, E Varin, H Lincet, L Poulain, ...
Anticancer research 31 (3), 797-805, 2011
952011
Comparative proteomic analysis of cisplatin sensitive IGROV1 ovarian carcinoma cell line and its resistant counterpart IGROV1‐R10
K Le Moguen, H Lincet, E Deslandes, M Hubert‐Roux, C Lange, ...
Proteomics 6 (19), 5183-5192, 2006
942006
Towards a new standardized method for circulating miRNAs profiling in clinical studies: Interest of the exogenous normalization to improve miRNA signature accuracy
N Vigneron, M Meryet-Figuière, A Guttin, JP Issartel, B Lambert, M Briand, ...
Molecular oncology 10 (7), 981-992, 2016
902016
Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells
K Simonin, E Brotin, S Dufort, S Dutoit, D Goux, M N'diaye, C Denoyelle, ...
Molecular cancer therapeutics 8 (11), 3162-3170, 2009
842009
Comet assay and DNA flow cytometry analysis of staurosporine‐induced apoptosis
T Godard, E Deslandes, P Lebailly, C Vigreux, L Poulain, F Sichel, ...
Cytometry: The Journal of the International Society for Analytical Cytology …, 1999
821999
Downregulation of Bcl-x L and Mcl-1 is sufficient to induce cell death in mesothelioma cells highly refractory to conventional chemotherapy
E Varin, C Denoyelle, E Brotin, M Meryet-Figuiere, F Giffard, E Abeilard, ...
Carcinogenesis 31 (6), 984-993, 2010
812010
Altered adhesion properties and alpha v integrin expression in a cisplatin‐resistant human ovarian carcinoma cell line
S Maubant, S Cruet‐Hennequart, L Poulain, F Carreiras, F Sichel, J Luis, ...
International journal of cancer 97 (2), 186-194, 2002
802002
Intraperitoneal linear polyethylenimine (L-PEI)-mediated gene delivery to ovarian carcinoma nodes in mice
MH Louis, S Dutoit, Y Denoux, P Erbacher, E Deslandes, JP Behr, ...
Cancer gene therapy 13 (4), 367-374, 2006
782006
Acquisition of chemoresistance following discontinuous exposures to cisplatin is associated in ovarian carcinoma cells with progressive alteration of FAK, ERK and p38 …
M Villedieu, E Deslandes, M Duval, JF Héron, P Gauduchon, L Poulain
Gynecologic oncology 101 (3), 507-519, 2006
742006
An overview of long non-coding RNAs in ovarian cancers
M Meryet-Figuière, B Lambert, P Gauduchon, N Vigneron, E Brotin, ...
Oncotarget 7 (28), 44719, 2016
642016
Vitronectin and its receptors partly mediate adhesion of ovarian cancer cells to peritoneal mesothelium in vitro
L Heyman, S Kellouche, J Fernandes, S Dutoit, L Poulain, F Carreiras
Tumor Biology 29 (4), 231-244, 2008
642008
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