| Early postnatal development of pyramidal neurons across layers of the mouse medial prefrontal cortex T Kroon, E van Hugte, L van Linge, HD Mansvelder, RM Meredith Scientific reports 9 (1), 5037, 2019 | 130 | 2019 |
| Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro B Mossink, AHA Verboven, EJH Van Hugte, TMK Gunnewiek, G Parodi, ... Stem cell reports 16 (9), 2182-2196, 2021 | 113 | 2021 |
| Neuron-glia interactions increase neuronal phenotypes in tuberous sclerosis complex patient iPSC-derived models AG Nadadhur, M Alsaqati, L Gasparotto, P Cornelissen-Steijger, ... Stem cell reports 12 (1), 42-56, 2019 | 90 | 2019 |
| NIPT‐based screening for Down syndrome and beyond: what do pregnant women think? RV van Schendel, WJ Dondorp, DRM Timmermans, EJH van Hugte, ... Prenatal diagnosis 35 (6), 598-604, 2015 | 88 | 2015 |
| Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks B Mossink, JR Van Rhijn, S Wang, K Linda, MR Vitale, JEM Zöller, ... Molecular Psychiatry 27 (1), 1-18, 2022 | 82 | 2022 |
| m. 3243A> G-induced mitochondrial dysfunction impairs human neuronal development and reduces neuronal network activity and synchronicity TMK Gunnewiek, EJH Van Hugte, M Frega, GS Guardia, K Foreman, ... Cell reports 31 (3), 2020 | 75 | 2020 |
| Excitatory/inhibitory balance in epilepsies and neurodevelopmental disorders: Depolarizing γ‐aminobutyric acid as a common mechanism EJH van van Hugte, D Schubert, N Nadif Kasri Epilepsia 64 (8), 1975-1990, 2023 | 34 | 2023 |
| SCN1A-deficient excitatory neuronal networks display mutation-specific phenotypes EJH Van Hugte, EI Lewerissa, KM Wu, N Scheefhals, G Parodi, ... Brain 146 (12), 5153-5167, 2023 | 22 | 2023 |
| Mitochondrial dysfunction impairs human neuronal development and reduces neuronal network activity and synchronicity TM Klein Gunnewiek, EJH Van Hugte, M Frega, GS Guardia, KB Foreman, ... bioRxiv, 720227, 2019 | 12* | 2019 |
| Neuronal network activity and connectivity are impaired in a conditional knockout mouse model with PCDH19 mosaic expression G Giansante, S Mazzoleni, AG Zippo, L Ponzoni, A Ghilardi, G Maiellano, ... Molecular Psychiatry 29 (6), 1710-1725, 2024 | 11 | 2024 |
| ANK2 loss-of-function variants are associated with epilepsy, and lead to impaired axon initial segment plasticity and hyperactive network activity in hiPSC-derived … MWA Teunissen, E Lewerissa, EJH van Hugte, S Wang, CW Ockeloen, ... Human molecular genetics 32 (14), 2373-2385, 2023 | 11 | 2023 |
| An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1. 1 underlying Dravet syndrome N Doorn, EJH van Hugte, U Ciptasari, A Mordelt, HGE Meijer, D Schubert, ... Stem cell reports 18 (8), 1686-1700, 2023 | 8 | 2023 |
| A human in vitro neuronal model for studying homeostatic plasticity at the network level X Yuan, S Puvogel, JR van Rhijn, U Ciptasari, A Esteve-Codina, M Meijer, ... Stem cell reports 18 (11), 2222-2239, 2023 | 6 | 2023 |
| Modeling psychiatric diseases with induced pluripotent stem cells E van Hugte, N Nadif Kasri Frontiers in Psychiatry: Artificial Intelligence, Precision Medicine, and …, 2019 | 6 | 2019 |
| Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment R Bhattacharjee, LA Jolly, MA Corbett, IC Wee, SR Rao, AE Gardner, ... Nature Communications 15 (1), 1210, 2024 | 2 | 2024 |
| SCN1A-deficient hiPSC-derived excitatory neuronal networks display mutation-specific phenotypes EJH van Hugte, EI Lewerissa, KM Wu, G Parodi, T van Voorst, N Kogo, ... bioRxiv, 2023.01. 11.523598, 2023 | 1 | 2023 |
| CHD2 Dosage Ties Autolysosomal Pathway to Cortical Maturation in Disease and Evolution O Leonardi, E Lewerissa, D Aprile, TS Barakat, L Culotta, R Deng, ... bioRxiv, 2025.01. 21.634145, 2025 | | 2025 |
| Patiënt-specifieke neuronale netwerken als modelsysteem voor Dravet syndroom E van Hugte Epilepsie, periodiek voor professionals 23 (2), 2024 | | 2024 |
| Exploring the Equilibrium between Seizure and Synchrony: Neuronal Network Development in Health and Disease EJH van Hugte Sl: sn, 2024 | | 2024 |
| The OTUD7A-Ankyrin pathway: a newly identified disease mechanism for the 15q13. 3 microdeletion disorder. N Scheefhals, UH Ciptasari, EJH van Hugte, N Nadif Kasri | | 2023 |
