Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism MB Yaffe, M Schutkowski, M Shen, XZ Zhou, PT Stukenberg, JU Rahfeld, ... Science 278 (5345), 1957-1960, 1997 | 1025 | 1997 |
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein PJ Lu, G Wulf, XZ Zhou, P Davies, KP Lu Nature 399 (6738), 784-788, 1999 | 961 | 1999 |
Function of WW domains as phosphoserine-or phosphothreonine-binding modules PJ Lu, XZ Zhou, M Shen, KP Lu Science 283 (5406), 1325-1328, 1999 | 906 | 1999 |
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease KP Lu, XZ Zhou Nature reviews Molecular cell biology 8 (11), 904-916, 2007 | 799 | 2007 |
Regulation of Raf-1 by direct feedback phosphorylation MK Dougherty, J Müller, DA Ritt, M Zhou, XZ Zhou, TD Copeland, ... Molecular cell 17 (2), 215-224, 2005 | 797 | 2005 |
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins XZ Zhou, O Kops, A Werner, PJ Lu, M Shen, G Stoller, G Küllertz, M Stark, ... Molecular cell 6 (4), 873-883, 2000 | 724 | 2000 |
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-β production L Pastorino, A Sun, PJ Lu, XZ Zhou, M Balastik, G Finn, G Wulf, J Lim, ... Nature 440 (7083), 528-534, 2006 | 604 | 2006 |
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration YC Liou, A Sun, A Ryo, XZ Zhou, ZX Yu, HK Huang, T Uchida, R Bronson, ... Nature 424 (6948), 556-561, 2003 | 539 | 2003 |
The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response H Zheng, H You, XZ Zhou, SA Murray, T Uchida, G Wulf, L Gu, X Tang, ... Nature 419 (6909), 849-853, 2002 | 501 | 2002 |
The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor XZ Zhou, KP Lu Cell 107 (3), 347-359, 2001 | 482 | 2001 |
Pinning down proline-directed phosphorylation signaling KP Lu, YC Liou, XZ Zhou Trends in cell biology 12 (4), 164-172, 2002 | 480 | 2002 |
Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy A Kondo, K Shahpasand, R Mannix, J Qiu, J Moncaster, CH Chen, Y Yao, ... Nature 523 (7561), 431-436, 2015 | 451 | 2015 |
Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model CA Tagge, AM Fisher, OV Minaeva, A Gaudreau-Balderrama, ... Brain 141 (2), 422-458, 2018 | 446 | 2018 |
Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins YC Liou, XZ Zhou, KP Lu Trends in biochemical sciences 36 (10), 501-514, 2011 | 380 | 2011 |
Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function PJ Lu, XZ Zhou, YC Liou, JP Noel, KP Lu Journal of Biological Chemistry 277 (4), 2381-2384, 2002 | 323 | 2002 |
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: a redox proteomics analysis R Sultana, D Boyd-Kimball, HF Poon, J Cai, WM Pierce, JB Klein, ... Neurobiology of aging 27 (7), 918-925, 2006 | 312 | 2006 |
Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease K Nakamura, A Greenwood, L Binder, EH Bigio, S Denial, L Nicholson, ... Cell 149 (1), 232-244, 2012 | 300 | 2012 |
Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer S Wei, S Kozono, L Kats, M Nechama, W Li, J Guarnerio, M Luo, MH You, ... Nature medicine 21 (5), 457-466, 2015 | 283 | 2015 |
The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target XZ Zhou, KP Lu Nature Reviews Cancer 16 (7), 463-478, 2016 | 266 | 2016 |
Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization M Nakamura, XZ Zhou, KP Lu Current Biology 11 (13), 1062-1067, 2001 | 258 | 2001 |