Directed differentiation of human embryonic stem cells into functional hepatic cells J Cai, Y Zhao, Y Liu, F Ye, Z Song, H Qin, S Meng, Y Chen, R Zhou, ... Hepatology 45 (5), 1229-1239, 2007 | 830 | 2007 |
Two supporting factors greatly improve the efficiency of human iPSC generation Y Zhao, X Yin, H Qin, F Zhu, H Liu, W Yang, Q Zhang, C Xiang, P Hou, ... Cell stem cell 3 (5), 475-479, 2008 | 640 | 2008 |
Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells Z Song, J Cai, Y Liu, D Zhao, J Yong, S Duo, X Song, Y Guo, Y Zhao, ... Cell research 19 (11), 1233-1242, 2009 | 634 | 2009 |
Small molecules enhance CRISPR genome editing in pluripotent stem cells C Yu, Y Liu, T Ma, K Liu, S Xu, Y Zhang, H Liu, M La Russa, M Xie, S Ding, ... Cell stem cell 16 (2), 142-147, 2015 | 507 | 2015 |
Development of CRISPR as an antiviral strategy to combat SARS-CoV-2 and influenza TR Abbott, G Dhamdhere, Y Liu, X Lin, L Goudy, L Zeng, A Chemparathy, ... Cell 181 (4), 865-876. e12, 2020 | 494 | 2020 |
Regulation of apoptosis and differentiation by p53 in human embryonic stem cells H Qin, T Yu, T Qing, Y Liu, Y Zhao, J Cai, J Li, Z Song, X Qu, P Zhou, J Wu, ... Journal of Biological Chemistry 282 (8), 5842-5852, 2007 | 310 | 2007 |
CRISPR-mediated live imaging of genome editing and transcription H Wang, M Nakamura, TR Abbott, D Zhao, K Luo, C Yu, CM Nguyen, A Lo, ... Science 365 (6459), 1301-1305, 2019 | 262 | 2019 |
CRISPR-mediated programmable 3D genome positioning and nuclear organization H Wang, X Xu, CM Nguyen, Y Liu, Y Gao, X Lin, T Daley, NH Kipniss, ... Cell 175 (5), 1405-1417. e14, 2018 | 210 | 2018 |
YAP induces human naive pluripotency H Qin, M Hejna, Y Liu, M Percharde, M Wossidlo, L Blouin, ... Cell reports 14 (10), 2301-2312, 2016 | 205 | 2016 |
CRISPR activation screens systematically identify factors that drive neuronal fate and reprogramming Y Liu, C Yu, TP Daley, F Wang, WS Cao, S Bhate, X Lin, C Still, H Liu, ... Cell stem cell 23 (5), 758-771. e8, 2018 | 200 | 2018 |
CRISPR-based chromatin remodeling of the endogenous Oct4 or Sox2 locus enables reprogramming to pluripotency P Liu, M Chen, Y Liu, LS Qi, S Ding Cell stem cell 22 (2), 252-261. e4, 2018 | 198 | 2018 |
A novel chemical-defined medium with bFGF and N2B27 supplements supports undifferentiated growth in human embryonic stem cells Y Liu, Z Song, Y Zhao, H Qin, J Cai, H Zhang, T Yu, S Jiang, G Wang, ... Biochemical and biophysical research communications 346 (1), 131-139, 2006 | 180 | 2006 |
Generation of Homogeneous PDX1+ Pancreatic Progenitors from Human ES Cell-derived Endoderm Cells J Cai, C Yu, Y Liu, S Chen, Y Guo, J Yong, W Lu, M Ding, H Deng Journal of molecular cell biology 2 (1), 50-60, 2010 | 153 | 2010 |
A single-chain photoswitchable CRISPR-Cas9 architecture for light-inducible gene editing and transcription XX Zhou, X Zou, HK Chung, Y Gao, Y Liu, LS Qi, MZ Lin ACS chemical biology 13 (2), 443-448, 2018 | 139 | 2018 |
Transcription factor competition allows embryonic stem cells to distinguish authentic signals from noise C Sokolik, Y Liu, D Bauer, J McPherson, M Broeker, G Heimberg, LS Qi, ... Cell systems 1 (2), 117-129, 2015 | 89 | 2015 |
Nested epistasis enhancer networks for robust genome regulation X Lin, Y Liu, S Liu, X Zhu, L Wu, Y Zhu, D Zhao, X Xu, A Chemparathy, ... Science 377 (6610), 1077-1085, 2022 | 82 | 2022 |
Induction of neutralizing antibody against human immunodeficiency virus type 1 (HIV-1) by immunization with gp41 membrane-proximal external region (MPER) fused with porcine … M Luo, F Yuan, Y Liu, S Jiang, X Song, P Jiang, X Yin, M Ding, H Deng Vaccine 24 (4), 435-442, 2006 | 55 | 2006 |
Retinoic acid enhances the generation of hematopoietic progenitors from human embryonic stem cell–derived hemato-vascular precursors C Yu, Y Liu, Z Miao, M Yin, W Lu, Y Lv, M Ding, H Deng Blood, The Journal of the American Society of Hematology 116 (23), 4786-4794, 2010 | 53 | 2010 |
Broad-spectrum CRISPR-mediated inhibition of SARS-CoV-2 variants and endemic coronaviruses in vitro L Zeng, Y Liu, XH Nguyenla, TR Abbott, M Han, Y Zhu, A Chemparathy, ... Nature communications 13 (1), 2766, 2022 | 48 | 2022 |
CRISPhieRmix: a hierarchical mixture model for CRISPR pooled screens TP Daley, Z Lin, X Lin, Y Liu, WH Wong, LS Qi Genome Biology 19, 1-13, 2018 | 48 | 2018 |