Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents X Gao, Y Tao, V Lamas, M Huang, WH Yeh, B Pan, YJ Hu, JH Hu, ... Nature 553 (7687), 217-221, 2018 | 569 | 2018 |
Engineering the delivery system for CRISPR-based genome editing Z Glass, M Lee, Y Li, Q Xu Trends in Biotechnology 36 (2), 173-185, 2018 | 372 | 2018 |
Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3 M Qiu, Z Glass, J Chen, X Zhao, X Rui, Z Ye, Y Li, F Zhang, Q Xu Proceedings of the National Academy of Sciences 118, e2020401118, 2021 | 324 | 2021 |
Lipid Nanoparticle-mediated Lymph Node-Targeting Delivery of mRNA Cancer Vaccine Elicits Robust CD8+ T Cell Response J Chen, Z Ye, C Huang, M Qiu, D Song, Y Li, Q Xu Proceedings of the National Academy of Sciences 119 (34), e2207841119, 2022 | 296 | 2022 |
Enzyme‐responsive polymeric vesicles for bacterial‐strain‐selective delivery of antimicrobial agents Y Li, G Liu, X Wang, J Hu, S Liu Angewandte Chemie International Edition 55 (5), 1760-1764, 2016 | 286 | 2016 |
Imidazole‐Based Synthetic Lipidoids for In Vivo mRNA Delivery into Primary T Lymphocytes X Zhao, J Chen, M Qiu, Y Li, Z Glass, Q Xu Angewandte Chemie International Edition 59 (45), 20083-20089, 2020 | 140 | 2020 |
Amphiphilic star copolymer‐based bimodal fluorogenic/magnetic resonance probes for concomitant bacteria detection and inhibition Y Li, H Yu, Y Qian, J Hu, S Liu Advanced Materials 26 (39), 6734-6741, 2014 | 140 | 2014 |
Cytosolic NQO1 Enzyme-Activated Near-Infrared Fluorescence Imaging and Photodynamic Therapy with Polymeric Vesicles C Yao, Y Li, Z Wang, C Song, X Hu, S Liu ACS Nano 14 (2), 1919-1935, 2020 | 131 | 2020 |
Ex vivo cell-based CRISPR/Cas9 genome editing for therapeutic applications Y Li, Z Glass, M Huang, ZY Chen, Q Xu Biomaterials 234, 119711, 2020 | 123 | 2020 |
Light-triggered concomitant enhancement of magnetic resonance imaging contrast performance and drug release rate of functionalized amphiphilic diblock copolymer micelles Y Li, Y Qian, T Liu, G Zhang, S Liu Biomacromolecules 13 (11), 3877-3886, 2012 | 107 | 2012 |
Developing Biodegradable Lipid Nanoparticles for Intracellular mRNA Delivery and Genome Editing M Qiu, Y Li, H Bloomer, Q Xu Accounts of Chemical Research 54 (21), 4001–4011, 2021 | 98 | 2021 |
In situ cancer vaccination using lipidoid nanoparticles J Chen, M Qiu, Z Ye, T Nyalile, Y Li, Z Glass, X Zhao, L Yang, J Chen, ... Science Advances 7, eabf1244, 2021 | 89 | 2021 |
Intracellular delivery and biodistribution study of CRISPR/Cas9 ribonucleoprotein loaded bioreducible lipidoid nanoparticles Y Li, J Bolinger, Y Yu, Z Glass, N Shi, L Yang, M Wang, Q Xu Biomaterials Science 7 (2), 596-606, 2019 | 85 | 2019 |
Polyion complex micellar nanoparticles for integrated fluorometric detection and bacteria inhibition in aqueous media Y Li, X Hu, S Tian, Y Li, G Zhang, G Zhang, S Liu Biomaterials 35 (5), 1618-1626, 2014 | 81 | 2014 |
Scaffold-mediated CRISPR/Cas9 delivery system for acute myeloid leukemia therapy TC Ho, HS Kim, Y Chen, Y Li, M LaMere, C Chen, H Wang, J Gong, ... Science Advances 7 (21), eabg3217, 2021 | 80 | 2021 |
Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteins Y Li, T Yang, Y Yu, N Shi, L Yang, Z Glass, J Bolinger, IJ Finkel, W Li, ... Biomaterials 178, 652-662, 2018 | 78 | 2018 |
Nanoparticles for CRISPR–Cas9 delivery Z Glass, Y Li, Q Xu Nature Biomedical Engineering 1 (11), 854-855, 2017 | 66 | 2017 |
In Vitro Engineering Chimeric Antigen Receptor Macrophages and T Cells by Lipid Nanoparticle-Mediated mRNA Delivery Z Ye, J Chen, X Zhao, Y Li, J Harmon, C Huang, J Chen, Q Xu ACS Biomaterials Science & Engineering 8 (2), 722-733, 2022 | 65 | 2022 |
Tailoring Combinatorial Lipid Nanoparticles for Intracellular Delivery of Nucleic Acids, Proteins, and Drugs Y Li, Z Ye, G Yang, Q Xu Acta Pharmaceutica Sinica B 12 (6), 2624-2639, 2022 | 62 | 2022 |
Challenges in delivering therapeutic peptides and proteins: A silk-based solution J Wu, J Sahoo, Y Li, Q Xu, D Kaplan Journal of Controlled Release 345, 176-189, 2022 | 62 | 2022 |