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Gemma Di Pompo
Gemma Di Pompo
Rizzoli Orthopaedic Institute
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Sarcoma treatment in the era of molecular medicine
TGP Grünewald, M Alonso, S Avnet, A Banito, S Burdach, F Cidre‐Aranaz, ...
EMBO molecular medicine 12 (11), e11131, 2020
2382020
Energy metabolism in osteoclast formation and activity
S Lemma, M Sboarina, PE Porporato, N Zini, P Sonveaux, G Di Pompo, ...
The international journal of biochemistry & cell biology 79, 168-180, 2016
2052016
Cancer‐associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF‐κB activation
S Avnet, G Di Pompo, T Chano, C Errani, A Ibrahim‐Hashim, RJ Gillies, ...
International journal of cancer 140 (6), 1331-1345, 2017
1432017
V-ATPase is a candidate therapeutic target for Ewing sarcoma
S Avnet, G Di Pompo, S Lemma, M Salerno, F Perut, G Bonuccelli, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (8 …, 2013
802013
Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells
G Di Pompo, M Salerno, D Rotili, S Valente, C Zwergel, S Avnet, ...
Journal of medicinal chemistry 58 (9), 4073-4079, 2015
792015
MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases
S Lemma, G Di Pompo, PE Porporato, M Sboarina, S Russell, RJ Gillies, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (12 …, 2017
642017
Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates
G Ciapetti, G Di Pompo, S Avnet, D Martini, A Diez-Escudero, EB Montufar, ...
Acta biomaterialia 50, 102-113, 2017
502017
Intratumoral acidosis fosters cancer-induced bone pain through the activation of the mesenchymal tumor-associated stroma in bone metastasis from breast carcinoma
G Di Pompo, S Lemma, L Canti, N Rucci, M Ponzetti, C Errani, DM Donati, ...
Oncotarget 8 (33), 54478, 2017
432017
Cause and effect of microenvironmental acidosis on bone metastases
S Avnet, G Di Pompo, S Lemma, N Baldini
Cancer and Metastasis Reviews 38, 133-147, 2019
412019
Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment
F Perut, F Carta, G Bonuccelli, G Grisendi, G Di Pompo, S Avnet, ...
Expert opinion on therapeutic targets 19 (12), 1593-1605, 2015
372015
Potassium citrate prevents increased osteoclastogenesis resulting from acidic conditions: Implication for the treatment of postmenopausal bone loss
D Granchi, E Torreggiani, A Massa, R Caudarella, G Di Pompo, N Baldini
PloS one 12 (7), e0181230, 2017
362017
3D printing and bioprinting to model bone cancer: the role of materials and nanoscale cues in directing cell behavior
T Fischetti, G Di Pompo, N Baldini, S Avnet, G Graziani
Cancers 13 (16), 4065, 2021
332021
Pre-clinical models for studying the interaction between mesenchymal stromal cells and cancer cells and the induction of stemness
S Avnet, S Lemma, M Cortini, G Di Pompo, F Perut, N Baldini
Frontiers in Oncology 9, 305, 2019
332019
Synthesis, characterization and biological activity of hydroxyl-bisphosphonic analogs of bile acids
O Bortolini, G Fantin, M Fogagnolo, S Rossetti, L Maiuolo, G Di Pompo, ...
European journal of medicinal chemistry 52, 221-229, 2012
302012
Acid microenvironment in bone sarcomas
G Di Pompo, M Cortini, N Baldini, S Avnet
Cancers 13 (15), 3848, 2021
282021
Low toxicity and unprecedented anti-osteoclast activity of a simple sulfur-containing gem-bisphosphonate: a comparative study
D Granchi, A Scarso, G Bianchini, A Chiminazzo, A Minto, P Sgarbossa, ...
European Journal of Medicinal Chemistry 65, 448-455, 2013
262013
Comparative “in vitro” evaluation of the antiresorptive activity residing in four Ayurvedic medicinal plants. Hemidesmus indicus emerges for its potential in the treatment of …
G Di Pompo, F Poli, M Mandrone, B Lorenzi, L Roncuzzi, N Baldini, ...
Journal of ethnopharmacology 154 (2), 462-470, 2014
212014
The release of inflammatory mediators from acid-stimulated mesenchymal stromal cells favours tumour invasiveness and metastasis in osteosarcoma
S Avnet, S Lemma, M Cortini, G Di Pompo, F Perut, MV Lipreri, ...
Cancers 13 (22), 5855, 2021
202021
Exploring metabolic adaptations to the acidic microenvironment of osteosarcoma cells unveils sphingosine 1-phosphate as a valuable therapeutic target
M Cortini, A Armirotti, M Columbaro, DL Longo, G Di Pompo, E Cannas, ...
Cancers 13 (2), 311, 2021
202021
Focus ion beam/scanning electron microscopy characterization of osteoclastic resorption of calcium phosphate substrates
A Diez-Escudero, M Espanol, EB Montufar, G Di Pompo, G Ciapetti, ...
Tissue Engineering Part C: Methods 23 (2), 118-124, 2017
182017
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