BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway EJ Pone, J Zhang, T Mai, CA White, G Li, JK Sakakura, PJ Patel, ... Nature communications 3 (1), 767, 2012 | 333 | 2012 |
Interleukin-1 receptor antagonist (IL-1Ra) and IL-1Ra producing mesenchymal stem cells as modulators of diabetogenesis V Volarevic, A Al-Qahtani, N Arsenijevic, S Pajovic, ML Lukic Autoimmunity 43 (4), 255-263, 2010 | 241 | 2010 |
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation SR Park, H Zan, Z Pal, J Zhang, A Al-Qahtani, EJ Pone, Z Xu, T Mai, ... Nature immunology 10 (5), 540-550, 2009 | 186 | 2009 |
14-3-3 adaptor proteins recruit AID to 5′-AGCT-3′–rich switch regions for class switch recombination Z Xu, Z Fulop, G Wu, EJ Pone, J Zhang, T Mai, LM Thomas, A Al-Qahtani, ... Nature structural & molecular biology 17 (9), 1124-1135, 2010 | 172 | 2010 |
Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses EJ Pone, H Zan, J Zhang, A Al-Qahtani, Z Xu, P Casali Critical Reviews™ in Immunology 30 (1), 2010 | 170 | 2010 |
Regulation of aicda Expression and AID Activity: Relevance to Somatic Hypermutation and Class Switch DNA Recombination Z Xu, EJ Pone, A Al-Qahtani, SR Park, H Zan, P Casali Critical Reviews™ in Immunology 27 (4), 2007 | 147 | 2007 |
The translesion DNA polymerase θ plays a dominant role in immunoglobulin gene somatic hypermutation H Zan, N Shima, Z Xu, A Al‐Qahtani, AJ Evinger III, Y Zhong, ... The EMBO journal 24 (21), 3757-3769, 2005 | 143 | 2005 |
Insulin resistance in macrophages alters their metabolism and promotes an M2-like phenotype E Ieronymaki, EM Theodorakis, K Lyroni, E Vergadi, E Lagoudaki, ... The Journal of Immunology 202 (6), 1786-1797, 2019 | 81 | 2019 |
AID dysregulation in lupus-prone MRL/Fas lpr/lpr mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4 CA White, J Seth Hawkins, EJ Pone, ES Yu, A Al-Qahtani, T Mai, H Zan, ... Autoimmunity 44 (8), 585-598, 2011 | 41 | 2011 |
Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions H Zan, J Zhang, A Al-Qahtani, EJ Pone, CA White, D Lee, L Yel, T Mai, ... Molecular immunology 48 (4), 610-622, 2011 | 29 | 2011 |
A role for DRAK2 in the germinal center reaction and the antibody response A Al-Qahtani, Z Xu, H Zan, CM Walsh, P Casali Autoimmunity 41 (5), 341-352, 2008 | 15 | 2008 |
Feasibility of intraocular projection for treatment of intractable corneal opacity SY Shim, S Gong, MI Rosenblatt, D Palanker, A Al-Qahtani, MG Sun, ... Cornea 38 (4), 523-527, 2019 | 14 | 2019 |
Characterization of an electronic corneal prosthesis system SY Shim, S Gong, VH Fan, MI Rosenblatt, AF Al-Qahtani, MG Sun, Q Zhou, ... Current eye research 45 (8), 914-920, 2020 | 4 | 2020 |
Flexible Acrylic Keratoprosthesis C Yu, A Al-Qahtani, M Rosenblatt Investigative Ophthalmology & Visual Science 58 (8), 5705-5705, 2017 | | 2017 |
AID dysregulation in lupus-prone MRL/Faslpr/lpr mice promotes interchromosomal c-Myc/IgH loci translocations, increased class switch DNA recombination and production of anti … C White, J Hawkins, E Pone, A Al-Qahtani, T Mai, H Zan, P Casali The Journal of Immunology 186 (1_Supplement), 148.25-148.25, 2011 | | 2011 |
The p85α regulatory subunit of phosphatidylinositol 3‐kinase critically modulates class switch DNA recombination Z Xu, J Zhang, YW Ho, YW Ho, A Al‐Qahtani, E Pone, H Zan, P Casali The FASEB Journal 22, 849.8-849.8, 2008 | | 2008 |
The recurring AGCT motif in S region DNA specifically recruits 14‐3‐3 adaptor proteins that are critical for the unfolding of CSR Z Xu, Z Fulop, J Zhang, A Al‐Qahtani, E Pone, Z Pal, SR Park, H Zan, ... The FASEB Journal 22, 849.9-849.9, 2008 | | 2008 |
The evolutionary conserved HoxC4 homeodomain protein induces AID expression and regulates immunoglobulin class switch DNA recombination and somatic hypermutation SR Park, Z Pal, A Al‐Qahtani, T Mai, Z Xu, H Zan, P Casali The FASEB Journal 22, 1066.15-1066.15, 2008 | | 2008 |
The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene H Zan, N Shima, Z Xu, A Al-Qahtani, AJ Evinger, JC Schimenti, P Casali JOURNAL OF IMMUNOLOGY 176, S234-S234, 2006 | | 2006 |
A critical role for DRAK2 in the germinal center reaction and antibody response A Al-Qahtani, J Xu, C Walsh, P Casali JOURNAL OF IMMUNOLOGY 176, S161-S161, 2006 | | 2006 |