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RNA structure analysis at single nucleotide resolution by selective 2 ‘-hydroxyl acylation and primer extension (SHAPE) EJ Merino, KA Wilkinson, JL Coughlan, KM Weeks Journal of the American Chemical Society 127 (12), 4223-4231, 2005 | 969 | 2005 |
Selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE): quantitative RNA structure analysis at single nucleotide resolution KA Wilkinson, EJ Merino, KM Weeks Nature protocols 1 (3), 1610-1616, 2006 | 939 | 2006 |
Accurate SHAPE-directed RNA structure determination KE Deigan, TW Li, DH Mathews, KM Weeks Proceedings of the National Academy of Sciences 106 (1), 97-102, 2009 | 803 | 2009 |
Principles for targeting RNA with drug-like small molecules KD Warner, CE Hajdin, KM Weeks Nature reviews Drug discovery 17 (8), 547-558, 2018 | 695 | 2018 |
RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP) NA Siegfried, S Busan, GM Rice, JAE Nelson, KM Weeks Nature methods 11 (9), 959-965, 2014 | 650 | 2014 |
Fragments of the HIV-1 Tat protein specifically biand TAR RNA KM Weeks, C Ampe, SC Schultz, TA Steitz, DM Crothers Science 249 (4974), 1281-1285, 1990 | 597 | 1990 |
mRNA structure determines specificity of a polyQ-driven phase separation EM Langdon, Y Qiu, A Ghanbari Niaki, GA McLaughlin, CA Weidmann, ... Science 360 (6391), 922-927, 2018 | 509 | 2018 |
High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states KA Wilkinson, RJ Gorelick, SM Vasa, N Guex, A Rein, DH Mathews, ... PLoS biology 6 (4), e96, 2008 | 481 | 2008 |
RNA recognition by Tat-derived peptides: interaction in the major groove? KM Weeks, DM Crothers Cell 66 (3), 577-588, 1991 | 442 | 1991 |
A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry SA Mortimer, KM Weeks Journal of the American Chemical Society 129 (14), 4144-4145, 2007 | 429 | 2007 |
Selective 2′-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile and accurate RNA structure analysis MJ Smola, GM Rice, S Busan, NA Siegfried, KM Weeks Nature protocols 10 (11), 1643-1669, 2015 | 397 | 2015 |
Accurate SHAPE-directed RNA secondary structure modeling, including pseudoknots CE Hajdin, S Bellaousov, W Huggins, CW Leonard, DH Mathews, ... Proceedings of the National Academy of Sciences 110 (14), 5498-5503, 2013 | 363 | 2013 |
Advances in RNA structure analysis by chemical probing KM Weeks Current opinion in structural biology 20 (3), 295-304, 2010 | 355 | 2010 |
SHAPE-directed RNA secondary structure prediction JT Low, KM Weeks Methods 52 (2), 150-158, 2010 | 343 | 2010 |
Genomic RNA elements drive phase separation of the SARS-CoV-2 nucleocapsid C Iserman, CA Roden, MA Boerneke, RSG Sealfon, GA McLaughlin, ... Molecular cell 80 (6), 1078-1091. e6, 2020 | 310 | 2020 |
RNA-Puzzles: a CASP-like evaluation of RNA three-dimensional structure prediction JA Cruz, MF Blanchet, M Boniecki, JM Bujnicki, SJ Chen, S Cao, R Das, ... Rna 18 (4), 610-625, 2012 | 309 | 2012 |
Catalysts from synthetic genetic polymers AI Taylor, VB Pinheiro, MJ Smola, AS Morgunov, S Peak-Chew, C Cozens, ... Nature 518 (7539), 427-430, 2015 | 299 | 2015 |
Major groove accessibility of RNA KM Weeks, DM Crothers Science 261 (5128), 1574-1577, 1993 | 268 | 1993 |
ShapeFinder: a software system for high-throughput quantitative analysis of nucleic acid reactivity information resolved by capillary electrophoresis SM Vasa, N Guex, KA Wilkinson, KM Weeks, MC Giddings Rna 14 (10), 1979-1990, 2008 | 264 | 2008 |