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Rolf T. Urbanus
Rolf T. Urbanus
Associate Professor, Van Creveldkliniek, UMC Utrecht, The Netherlands
Verificeret mail på umcutrecht.nl
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Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study
RT Urbanus, B Siegerink, M Roest, FR Rosendaal, PG de Groot, A Algra
The Lancet Neurology 8 (11), 998-1005, 2009
5372009
IgG antibodies that recognize epitope Gly40-Arg43 in domain I of β2–glycoprotein I cause LAC, and their presence correlates strongly with thrombosis
B De Laat, RHWM Derksen, RT Urbanus, PG De Groot
Blood 105 (4), 1540-1545, 2005
4832005
β2-Glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome
Ç Ağar, GMA van Os, M Mörgelin, RR Sprenger, JA Marquart, ...
Blood, The Journal of the American Society of Hematology 116 (8), 1336-1343, 2010
423*2010
β2-glycoprotein I–dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome
HB De Laat, RHWM Derksen, RT Urbanus, M Roest, PG de Groot
Blood 104 (12), 3598-3602, 2004
3022004
Swarm intelligence-enhanced detection of non-small-cell lung cancer using tumor-educated platelets
MG Best, N Sol, S GJG, A Vancura, M Muller, ALN Niemeijer, AV Fejes, ...
Cancer cell 32 (2), 238-252. e9, 2017
2832017
Antiphospholipid antibodies promote leukocyte–endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2
S Ramesh, CN Morrell, C Tarango, GD Thomas, IS Yuhanna, G Girardi, ...
The Journal of clinical investigation 121 (1), 120-131, 2011
2332011
The significance of autoantibodies against β2-glycoprotein I
PG de Groot, RT Urbanus
Blood, The Journal of the American Society of Hematology 120 (2), 266-274, 2012
1882012
Recent guidelines and recommendations for laboratory detection of lupus anticoagulants
GW Moore
Seminars in thrombosis and hemostasis 40 (02), 163-171, 2014
1822014
Platelet activation by dimeric β2‐glycoprotein I requires signaling via both glycoprotein Ibα and apolipoprotein E receptor 2′
RT Urbanus, MTT Pennings, R Derksen, PG De Groot
Journal of Thrombosis and Haemostasis 6 (8), 1405-1412, 2008
1572008
Platelet adhesion to dimeric β2‐glycoprotein I under conditions of flow is mediated by at least two receptors: glycoprotein Ibα and apolipoprotein E receptor 2′
MTT Pennings, R Derksen, M Van Lummel, J Adelmeijer, ...
Journal of Thrombosis and Haemostasis 5 (2), 369-377, 2007
1512007
Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome
Z Romay-Penabad, R Aguilar-Valenzuela, RT Urbanus, RHWM Derksen, ...
Blood, The Journal of the American Society of Hematology 117 (4), 1408-1414, 2011
1472011
Current insight into diagnostics and pathophysiology of the antiphospolipid syndrome
RT Urbanus, RHMW Derksen, PG de Groot
Blood reviews 22 (2), 93-105, 2008
1402008
Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells
XV Yang, Y Banerjee, JA Fernández, H Deguchi, X Xu, LO Mosnier, ...
Proceedings of the National Academy of Sciences 106 (1), 274-279, 2009
1252009
Immune responses against domain I of β2‐glycoprotein I are driven by conformational changes: Domain I of β2‐glycoprotein I harbors a cryptic immunogenic epitope
B de Laat, M van Berkel, RT Urbanus, B Siregar, PG de Groot, ...
Arthritis & Rheumatism 63 (12), 3960-3968, 2011
1242011
Interaction of β2-glycoprotein I with members of the low density lipoprotein receptor family
MTT Pennings, M Van Lummel, R Derksen, RT Urbanus, RA Romijn, ...
Journal of thrombosis and haemostasis 4 (8), 1680-1690, 2006
1042006
Interference with the host haemostatic system by schistosomes
MM Mebius, PJJ van Genderen, RT Urbanus, AGM Tielens, PG de Groot, ...
PLoS pathogens 9 (12), e1003781, 2013
972013
The binding site in β2-glycoprotein I for ApoER2′ on platelets is located in domain V
M van Lummel, MTT Pennings, RHWM Derksen, RT Urbanus, ...
Journal of Biological Chemistry 280 (44), 36729-36736, 2005
882005
ApoE receptor 2 mediation of trophoblast dysfunction and pregnancy complications induced by antiphospholipid antibodies in mice
V Ulrich, SE Gelber, M Vukelic, A Sacharidou, J Herz, RT Urbanus, ...
Arthritis & rheumatology 68 (3), 730-739, 2016
872016
Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2)
TC White-Adams, MA Berny, EI Tucker, JM Gertz, D Gailani, RT Urbanus, ...
Arteriosclerosis, thrombosis, and vascular biology 29 (10), 1602-1607, 2009
792009
Protein C supports platelet binding and activation under flow: role of glycoprotein Ib and apolipoprotein E receptor 2
TC White, MA Berny, EI Tucker, RT Urbanus, PG De Groot, JA Fernandez, ...
Journal of Thrombosis and Haemostasis 6 (6), 995-1002, 2008
782008
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Artikler 1–20