Linear ubiquitination prevents inflammation and regulates immune signalling B Gerlach, SM Cordier, AC Schmukle, CH Emmerich, E Rieser, TL Haas, ... Nature 471 (7340), 591-596, 2011 | 1015 | 2011 |
XIAP discriminates between type I and type II FAS-induced apoptosis PJ Jost, S Grabow, D Gray, MD McKenzie, U Nachbur, DCS Huang, ... Nature 460 (7258), 1035-1039, 2009 | 604 | 2009 |
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity RB Damgaard, U Nachbur, M Yabal, WWL Wong, BK Fiil, M Kastirr, ... Molecular cell 46 (6), 746-758, 2012 | 423 | 2012 |
A type III effector antagonizes death receptor signalling during bacterial gut infection JS Pearson, C Giogha, SY Ong, CL Kennedy, M Kelly, KS Robinson, ... Nature 501 (7466), 247-251, 2013 | 292 | 2013 |
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice JA Rickard, H Anderton, N Etemadi, U Nachbur, M Darding, N Peltzer, ... Elife 3, e03464, 2014 | 269 | 2014 |
RIPK1 is not essential for TNFR1-induced activation of NF-κB WWL Wong, IE Gentle, U Nachbur, H Anderton, DL Vaux, J Silke Cell Death & Differentiation 17 (3), 482-487, 2010 | 211 | 2010 |
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation JS Pearson, C Giogha, S Mühlen, U Nachbur, CLL Pham, Y Zhang, ... Nature microbiology 2 (4), 1-10, 2017 | 192 | 2017 |
RIPK1 suppresses a TRAF2-dependent pathway to liver cancer AT Schneider, J Gautheron, M Feoktistova, C Roderburg, SH Loosen, ... Cancer cell 31 (1), 94-109, 2017 | 156 | 2017 |
Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis G Ebert, C Allison, S Preston, J Cooney, JG Toe, MD Stutz, S Ojaimi, ... Proceedings of the National Academy of Sciences 112 (18), 5803-5808, 2015 | 142 | 2015 |
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production U Nachbur, CA Stafford, A Bankovacki, Y Zhan, LM Lindqvist, BK Fiil, ... Nature communications 6 (1), 6442, 2015 | 139 | 2015 |
Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus G Ebert, S Preston, C Allison, J Cooney, JG Toe, MD Stutz, S Ojaimi, ... Proceedings of the National Academy of Sciences 112 (18), 5797-5802, 2015 | 112 | 2015 |
Thiazolides inhibit growth and induce glutathione‐S‐transferase Pi (GSTP1)‐dependent cell death in human colon cancer cells J Müller, D Sidler, U Nachbur, J Wastling, T Brunner, A Hemphill International Journal of Cancer 123 (8), 1797-1806, 2008 | 105 | 2008 |
In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-κB and activation of caspase-8 IE Gentle, WWL Wong, JM Evans, A Bankovacki, WD Cook, NR Khan, ... Journal of Biological Chemistry 286 (15), 13282-13291, 2011 | 104 | 2011 |
TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1 N Etemadi, M Chopin, H Anderton, MC Tanzer, JA Rickard, W Abeysekera, ... elife 4, e10592, 2015 | 103 | 2015 |
NOD signaling and cell death VJ Heim, CA Stafford, U Nachbur Frontiers in cell and developmental biology 7, 208, 2019 | 101 | 2019 |
Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor N Etemadi, JK Holien, D Chau, G Dewson, JM Murphy, WS Alexander, ... The FEBS journal 280 (21), 5283-5297, 2013 | 78 | 2013 |
Inhibitor of apoptosis protein-1 regulates tumor necrosis factor–mediated destruction of intestinal epithelial cells T Grabinger, KJ Bode, J Demgenski, C Seitz, ME Delgado, F Kostadinova, ... Gastroenterology 152 (4), 867-879, 2017 | 76 | 2017 |
Oligomerization‐driven MLKL ubiquitylation antagonizes necroptosis Z Liu, LF Dagley, K Shield‐Artin, SN Young, A Bankovacki, X Wang, ... The EMBO journal 40 (23), e103718, 2021 | 58 | 2021 |
Progranulin does not inhibit TNF and lymphotoxin‐α signalling through TNF receptor 1 N Etemadi, A Webb, A Bankovacki, J Silke, U Nachbur Immunology and cell biology 91 (10), 661-664, 2013 | 51 | 2013 |
Epigenetic silencing of RIPK3 in hepatocytes prevents MLKL-mediated necroptosis from contributing to liver pathologies SP Preston, MD Stutz, CC Allison, U Nachbur, Q Gouil, BM Tran, ... Gastroenterology 163 (6), 1643-1657. e14, 2022 | 49 | 2022 |