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Ehab Al-Moubarak
Ehab Al-Moubarak
School of Physiology and Pharmacology and Neuroscience, University of Bristol
Verificeret mail på bristol.ac.uk
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SYMPOSIUM REVIEW: Gating of two pore domain potassium channels
A Mathie, E Al‐Moubarak, EL Veale
The Journal of physiology 588 (17), 3149-3156, 2010
1122010
Influence of the N terminus on the biophysical properties and pharmacology of TREK1 potassium channels
EL Veale, E Al-Moubarak, N Bajaria, K Omoto, L Cao, SJ Tucker, ...
Molecular pharmacology 85 (5), 671-681, 2014
682014
Recovery of current through mutated TASK3 potassium channels underlying Birk Barel syndrome
EL Veale, M Hassan, Y Walsh, E Al-Moubarak, A Mathie
Molecular pharmacology 85 (3), 397-407, 2014
482014
Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant
E Al-Moubarak, HA Shiels, Y Zhang, C Du, O Hanington, SC Harmer, ...
Cellular and Molecular Life Sciences 78, 7899-7914, 2021
222021
A homology model for Clostridium difficile methionyl tRNA synthetase: active site analysis and docking interactions
E Al-Moubarak, C Simons
Journal of molecular modeling 17, 1679-1693, 2011
152011
Serine mutation of a conserved threonine in the hERG K+ channel S6-pore region leads to loss-of-function through trafficking impairment
E Al-Moubarak, Y Zhang, CE Dempsey, H Zhang, SC Harmer, JC Hancox
Biochemical and Biophysical Research Communications 526 (4), 1085-1091, 2020
112020
In silico Exploration of Interactions Between Potential COVID-19 Antiviral Treatments and the Pore of the hERG Potassium Channel—A Drug Antitarget
E Al-Moubarak, M Sharifi, JC Hancox
Frontiers in Cardiovascular Medicine 8, 645172, 2021
72021
Pharmacologically reversible, loss of function mutations in the TM2 and TM4 inner pore helices of TREK-1 K2P channels
E Al-Moubarak, EL Veale, A Mathie
Scientific reports 9 (1), 12394, 2019
72019
Evaluating pro-arrhythmogenic effects of the T634S-hERG mutation: insights from a simulation study
W Hu, W Zhang, K Zhang, E Al-Moubarak, Y Zhang, SC Harmer, ...
Interface Focus 13 (6), 20230035, 2023
22023
Inhibition of hERG potassium channels by the polycylic aromatic hydrocarbon phenanthrene
E Al-Moubarak, H Shiels, Y Zhang, C Du, C Dempsey, J Hancox
Biophysical Journal 118 (3), 109a, 2020
22020
Regulation of TREK1 two pore domain potassium channels by citalopram
E Al‐Moubarak, EL Veale, A Mathie
The FASEB Journal 27, 913.31-913.31, 2013
22013
Enhancement of Current through Trek1 Two Pore Domain Channels by Flufenamic Acid
E Al-Moubarak, A Mathie
Biophysical Journal 106 (2), 748a, 2014
2014
Molecular Pharmacology Fast Forward. Published on February 7, 2014 as doi: 10.1124/mol. 113.091199
EL Veale, E Al-Moubarak, N Bajaria, K Omoto, L Cao, SJ Tucker, ...
2014
A homology model for methionyl tRNA synthetase: active site analysis and docking interactions
C Simons, E Al-Moubarak
Springer-Verlag, 2011
2011
Inhibition of The hERG Potassium Channel By The Polycyclic Aromatic Hydrocarbon Pollutant Phenanthrene
E Al-Moubarak, HA Shiels, Y Zhang, C Du, O Hanington, SC Harmer, ...
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Artikler 1–15