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David Bermudes
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Tumor-targeted Salmonella as a Novel Anticancer Vector
JM Pawelek, KB Low, D Bermudes
Cancer research 57 (20), 4537-4544, 1997
7701997
Tumour-targeting bacteria engineered to fight cancer
S Zhou, C Gravekamp, D Bermudes, K Liu
Nature Reviews Cancer 18 (12), 727-743, 2018
6522018
Lipid A mutant Salmonella with suppressed virulence and TNFα induction retain tumor-targeting in vivo
KB Low, M Ittensohn, T Le, J Platt, S Sodi, M Amoss, O Ash, E Carmichael, ...
Nature biotechnology 17 (1), 37-41, 1999
5911999
Biodistribution and Genetic Stability of the Novel Antitumor Agent VNP20009, a Genetically Modified Strain of Salmonella typhimuvium
C Clairmont, KC Lee, J Pike, M Ittensohn, KB Low, J Pawelek, ...
Journal of Infectious Diseases 181 (6), 1996-2002, 2000
4172000
Bacteria as tumour-targeting vectors
JM Pawelek, KB Low, D Bermudes
The lancet oncology 4 (9), 548-556, 2003
4152003
In vivo maintenance of synergistic cytarabine: daunorubicin ratios greatly enhances therapeutic efficacy
P Tardi, S Johnstone, N Harasym, S Xie, T Harasym, N Zisman, P Harvie, ...
Leukemia research 33 (1), 129-139, 2009
4012009
Kinetics and pattern of organelle exocytosis duringToxoplasma gondii/host-cell interaction
JF Dubremetz, A Achbarou, D Bermudes, KA Joiner
Parasitology research 79, 402-408, 1993
2611993
Symbiosis as a mechanism of evolution: status of cell symbiosis theory.
L Margulis, D Bermudes
Symbiosis (Philadelphia, Pa.) 1, 101-124, 1985
2561985
Use of preferentially replicating bacteria for the treatment of cancer
M Sznol, SL Lin, D Bermudes, L Zheng, I King
The Journal of clinical investigation 105 (8), 1027-1030, 2000
2552000
Tandemly repeated genes encode nucleoside triphosphate hydrolase isoforms secreted into the parasitophorous vacuole of Toxoplasma gondii.
D Bermudes, KR Peck, MA Afifi, CJ Beckers, KA Joiner
Journal of Biological Chemistry 269 (46), 29252-29260, 1994
1821994
Leukemia-selective uptake and cytotoxicity of CPX-351, a synergistic fixed-ratio cytarabine: daunorubicin formulation, in bone marrow xenografts
WS Lim, PG Tardi, N Dos Santos, X Xie, M Fan, BD Liboiron, X Huang, ...
Leukemia research 34 (9), 1214-1223, 2010
1742010
Antitumor effect of VNP20009, an attenuated Salmonella, in murine tumor models
S Shen, J Chen, IC King, L Zheng
Oncology research 12, 501-508, 2001
1632001
Melanoma× macrophage hybrids with enhanced metastatic potential
M Rachkovsky, S Sodi, A Chakraborty, Y Avissar, J Bolognia, ...
Clinical & experimental metastasis 16, 299-312, 1998
1611998
Modulating the therapeutic activity of nanoparticle delivered paclitaxel by manipulating the hydrophobicity of prodrug conjugates
SM Ansell, SA Johnstone, PG Tardi, L Lo, S Xie, Y Shu, TO Harasym, ...
Journal of medicinal chemistry 51 (11), 3288-3296, 2008
1582008
Drug ratio–dependent antitumor activity of irinotecan and cisplatin combinations in vitro and in vivo
PG Tardi, N Dos Santos, TO Harasym, SA Johnstone, N Zisman, ...
Molecular cancer therapeutics 8 (8), 2266-2275, 2009
1542009
Tumor-targeted Salmonella expressing cytosine deaminase as an anticancer agent
I King, D Bermudes, S Lin, M Belcourt, J Pike, K Troy, T Le, M Ittensohn, ...
Human gene therapy 13 (10), 1225-1233, 2002
1532002
Positron emission tomography (PET) imaging of tumor-localized Salmonella expressing HSV1-TK
SA Soghomonyan, M Doubrovin, J Pike, X Luo, M Ittensohn, JD Runyan, ...
Cancer gene therapy 12 (1), 101-108, 2005
1392005
Construction of VNP20009: a novel, genetically stable antibiotic-sensitive strain of tumor-targeting Salmonella for parenteral administration in humans
KB Low, M Ittensohn, X Luo, LM Zheng, I King, JM Pawelek, D Bermudes
Suicide Gene Therapy: Methods and Reviews, 47-59, 2004
1372004
Genetically modified tumor-targeted bacteria with reduced virulence
D Bermudes, KB Low, Vion Pharmaceuticals, Inc., Y University
US Patent 6,080,849, 2000
121*2000
Live bacteria as anticancer agents and tumor-selective protein delivery vectors.
D Bermudes, LM Zheng, IC King
Current opinion in drug discovery & development 5 (2), 194-199, 2002
1192002
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