Jan Böttcher

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Caetano Reis e SousaPrincipal Group Leader, The Francis Crick InstituteVerificeret mail på crick.ac.uk
Santiago ZelenayGroup Leader at CRUK Manchester InstituteVerificeret mail på cruk.manchester.ac.uk
Neil RogersThe Francis Crick InstituteVerificeret mail på crick.ac.uk
Erik SahaiFrancis Crick InstituteVerificeret mail på crick.ac.uk
Barbara SchramlWalter-Brendel-Centre for Experimental Medicine, Ludwig-Maximilians-University MunichVerificeret mail på med.uni-muenchen.de
Julie HelftInstitut CochinVerificeret mail på inserm.fr
Bastian HöchstTechnische Universität München, Institute of Molecular ImmunologyVerificeret mail på tum.de
Hanna BleesThe Francis Crick InstituteVerificeret mail på crick.ac.uk
Eduardo BonavitaHumanitas Research HospitalVerificeret mail på humanitasresearch.it
Stefano SammicheliSan Raffaele Scientific InstituteVerificeret mail på hsr.it
Mar Cabeza-CabrerizoSchmidt Science Postdoctoral Fellow, The University of CambridgeVerificeret mail på cam.ac.uk
Sergio A. QuezadaUCL Cancer InstituteVerificeret mail på ucl.ac.uk
Dr Sophie E. Acton (Pinner)Laboratory for Molecular Cell Biology, University College LondonVerificeret mail på ucl.ac.uk
Wolfgang KastenmullerProfessor for Systems Immunology, University WürzburgVerificeret mail på uni-wuerzburg.de
Christoph GarbersInstitute of Clinical Biochemistry, Hannover Medical School, GermanyVerificeret mail på mh-hannover.de
Matthias MannMax Planck Institute of Biochemistry, Munich and CPR, University of CopenhagenVerificeret mail på biochem.mpg.de
Daniel Robert EngelPhDVerificeret mail på immunodynamics.de
ProtzerProfessor for Virology, Technische Unversität München / Helmholtz Zentrum MünchenVerificeret mail på tum.de
Felix MeissnerProfessorVerificeret mail på uni-bonn.de
Sarah EickhoffInstitute of Experimental Oncology, University Hospital Bonn, GermanyVerificeret mail på ukbonn.de

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Jan Böttcher

Director Department of Experimental Immunology, University of Tübingen

Verificeret mail på tum.de - Startside

Immunology Cancer biology Cancer metastases Spatial biology Immunotherapy


Titel Sortér efter henvisninger Sortér efter årstal Sortér efter titel	Citeret af Citeret af	År
NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control JP Böttcher, E Bonavita, P Chakravarty, H Blees, M Cabeza-Cabrerizo, ... Cell, 2018	1690	2018
Cyclooxygenase-dependent tumor growth through evasion of immunity S Zelenay, AG Van Der Veen, JP Böttcher, KJ Snelgrove, N Rogers, ... Cell 162 (6), 1257-1270, 2015	1089	2015
GM-CSF mouse bone marrow cultures comprise a heterogeneous population of CD11c+ MHCII+ macrophages and dendritic cells J Helft, J Böttcher, P Chakravarty, S Zelenay, J Huotari, BU Schraml, ... Immunity 42 (6), 1197-1211, 2015	904	2015
Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH M Dudek, D Pfister, S Donakonda, P Filpe, A Schneider, M Laschinger, ... Nature 592 (7854), 444-449, 2021	370	2021
The role of type 1 conventional dendritic cells in cancer immunity JP Böttcher, C Reis e Sousa Trends in Cancer, 2018	332	2018
Functional classification of memory CD8⁺ T cells by CX₃CR1 expression JP Böttcher, M Beyer, F Meissner, Z Abdullah, J Sander, B Höchst, ... Nature communications 6 (1), 8306, 2015	294	2015
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation M Beyer, Y Thabet, RU Müller, T Sadlon, S Classen, K Lahl, S Basu, ... Nature immunology 12 (9), 898-907, 2011	241	2011
RIG‐I detects infection with live Listeria by sensing secreted bacterial nucleic acids Z Abdullah, M Schlee, S Roth, MA Mraheil, W Barchet, J Böttcher, T Hain, ... The EMBO journal 31 (21), 4153-4164, 2012	210	2012
Dynamic regulation of CD8 T cell tolerance induction by liver sinusoidal endothelial cells A Schurich, M Berg, D Stabenow, J Böttcher, M Kern, HJ Schild, C Kurts, ... The Journal of Immunology 184 (8), 4107-4114, 2010	156	2010
IL-6 trans-Signaling-Dependent Rapid Development of Cytotoxic CD8⁺ T Cell Function JP Böttcher, O Schanz, C Garbers, A Zaremba, S Hegenbarth, C Kurts, ... Cell reports 8 (5), 1318-1327, 2014	129	2014
Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity JP Böttcher, O Schanz, D Wohlleber, Z Abdullah, S Debey-Pascher, ... Cell reports 3 (3), 779-795, 2013	96	2013
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses F Bayerl, P Meiser, S Donakonda, A Hirschberger, SB Lacher, AM Pedde, ... Immunity 56 (6), 1341-1358. e11, 2023	93	2023
A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity P Meiser, MA Knolle, A Hirschberger, GP de Almeida, F Bayerl, S Lacher, ... Cancer Cell 41 (8), 1498-1515. e10, 2023	91	2023
Distinct kinetics and dynamics of cross‐presentation in liver sinusoidal endothelial cells compared to dendritic cells A Schurich, JP Böttcher, S Burgdorf, P Penzler, S Hegenbarth, M Kern, ... Hepatology 50 (3), 909-919, 2009	90	2009
TIMP1 triggers neutrophil extracellular trap formation in pancreatic cancer B Schoeps, C Eckfeld, O Prokopchuk, J Böttcher, D Häußler, K Steiger, ... Cancer Research 81 (13), 3568-3579, 2021	87	2021
Mechanisms balancing tolerance and immunity in the liver JP Böttcher, PA Knolle, D Stabenow Dig Dis 29, 384-390, 2011	84	2011
Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance toward circulating carcinoembryonic antigen in mice B Höchst, FA Schildberg, J Böttcher, C Metzger, S Huss, A Türler, ... Hepatology 56 (5), 1924-1933, 2012	77	2012
Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics JCR Simon Zenke, Margriet M. Palm, Julia Braun, Alina Gavrilov, Philippa ... Immunity, 2020	67	2020
PGE₂ inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function M Morotti, AJ Grimm, HC Hope, M Arnaud, M Desbuisson, N Rayroux, ... Nature, 1-9, 2024	57	2024
Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection S Flommersfeld, JP Böttcher, J Ersching, M Flossdorf, P Meiser, ... Immunity 54 (10), 2288-2304. e7, 2021	57	2021

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