| Small-molecule modulators of toll-like receptors Y Wang, S Zhang, H Li, H Wang, T Zhang, MR Hutchinson, H Yin, X Wang Accounts of chemical research 53 (5), 1046-1055, 2020 | 174 | 2020 |
| Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis Z Li, D Wang, J Lu, B Huang, Y Wang, M Dong, D Fan, H Li, Y Gao, P Hou, ... Cell Death & Differentiation 27 (12), 3226-3242, 2020 | 132 | 2020 |
| Hydrophobic plug functions as a gate in voltage-gated proton channels A Chamberlin, F Qiu, S Rebolledo, Y Wang, SY Noskov, HP Larsson Proceedings of the National Academy of Sciences 111 (2), E273-E282, 2014 | 89 | 2014 |
| A minimalist binary vaccine carrier for personalized postoperative cancer vaccine therapy J Zhao, Y Xu, S Ma, Y Wang, Z Huang, H Qu, H Yao, Y Zhang, G Wu, ... Advanced Materials 34 (10), 2109254, 2022 | 87 | 2022 |
| DNA-based platform for efficient and precisely targeted bioorthogonal catalysis in living systems Y You, Q Deng, Y Wang, Y Sang, G Li, F Pu, J Ren, X Qu Nature communications 13 (1), 1459, 2022 | 70 | 2022 |
| Sodium channel selectivity and conduction: prokaryotes have devised their own molecular strategy RK Finol-Urdaneta, Y Wang, A Al-Sabi, C Zhao, SY Noskov, RJ French Journal of General Physiology 143 (2), 157-171, 2014 | 69 | 2014 |
| Ivabradine prolongs phase 3 of cardiac repolarization and blocks the hERG1 (KCNH2) current over a concentration-range overlapping with that required to block HCN4 JP Lees-Miller, J Guo, Y Wang, LL Perissinotti, SY Noskov, HJ Duff Journal of molecular and cellular cardiology 85, 71-78, 2015 | 65 | 2015 |
| Kinetic and thermodynamic insights into sodium ion translocation through the μ-opioid receptor from molecular dynamics and machine learning analysis X Hu, Y Wang, A Hunkele, D Provasi, GW Pasternak, M Filizola PLoS computational biology 15 (1), e1006689, 2019 | 63 | 2019 |
| Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain Y Peng, X Zhang, T Zhang, PM Grace, H Li, Y Wang, H Li, H Chen, ... Brain, behavior, and immunity 82, 432-444, 2019 | 48 | 2019 |
| A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal‐induced arrhythmias PC Yang, LL Perissinotti, F López‐Redondo, Y Wang, KR DeMarco, ... The Journal of physiology 595 (14), 4695-4723, 2017 | 46 | 2017 |
| TLR4 biased small molecule modulators C Lin, H Wang, M Zhang, S Mustafa, Y Wang, H Li, H Yin, MR Hutchinson, ... Pharmacology & Therapeutics 228, 107918, 2021 | 42 | 2021 |
| Dissecting the innate immune recognition of opioid inactive isomer (+)-naltrexone derived toll-like receptor 4 (TLR4) antagonists X Zhang, F Cui, H Chen, T Zhang, K Yang, Y Wang, Z Jiang, KC Rice, ... Journal of chemical information and modeling 58 (4), 816-825, 2018 | 39 | 2018 |
| Mapping the gating and permeation pathways in the voltage-gated proton channel Hv1 A Chamberlin, F Qiu, Y Wang, SY Noskov, HP Larsson Journal of molecular biology 427 (1), 131-145, 2015 | 39 | 2015 |
| Role of the pH in state-dependent blockade of hERG currents Y Wang, J Guo, LL Perissinotti, J Lees-Miller, G Teng, S Durdagi, HJ Duff, ... Scientific Reports 6 (1), 32536, 2016 | 33 | 2016 |
| Cannabidiol alleviates neuroinflammation and attenuates neuropathic pain via targeting FKBP5 X Wang, C Lin, S Jin, Y Wang, Y Peng, X Wang Brain, behavior, and immunity 111, 365-375, 2023 | 28 | 2023 |
| A DNAzyme-augmented bioorthogonal catalysis system for synergistic cancer therapy Y You, H Liu, J Zhu, Y Wang, F Pu, J Ren, X Qu Chemical Science 13 (26), 7829-7836, 2022 | 28 | 2022 |
| One‐component artificial gustatory system based on hydrogen‐bond organic framework for discrimination of versatile analytes M Jiang, X Yan, Y Wang, F Pu, H Liu, Y Li, C Yang, J Zhu, X Liu, J Ren, ... Advanced Functional Materials 33 (24), 2300091, 2023 | 27 | 2023 |
| O-GlcNAcylation promotes the cytosolic localization of the m6A reader YTHDF1 and colorectal cancer tumorigenesis J Li, M Ahmad, L Sang, Y Zhan, Y Wang, Y Yan, Y Liu, W Mi, M Lu, Y Dai, ... Journal of Biological Chemistry 299 (6), 2023 | 22 | 2023 |
| Artemisinin inhibits TLR4 signaling by targeting co‐receptor MD2 in microglial BV‐2 cells and prevents lipopolysaccharide‐induced blood–brain barrier leakage in mice T Zhang, X Zhang, C Lin, S Wu, F Wang, H Wang, Y Wang, Y Peng, ... Journal of neurochemistry 157 (3), 611-623, 2021 | 22 | 2021 |
| Stereochemistry and innate immune recognition:(+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling X Zhang, Y Peng, PM Grace, MD Metcalf, AJ Kwilasz, Y Wang, T Zhang, ... The FASEB Journal 33 (8), 9577, 2019 | 19 | 2019 |
Xiaohui WangPrincipal Investigator (Professor), Chinese Academy of Sciences (CAS)Verificeret mail på ciac.ac.cn