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Frank Stefan Heldt
Frank Stefan Heldt
Verificeret mail på boehringer-ingelheim.com
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DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression
AR Barr, S Cooper, FS Heldt, F Butera, H Stoy, J Mansfeld, B Novák, ...
Nature communications 8 (1), 14728, 2017
3882017
Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection
FS Heldt, SY Kupke, S Dorl, U Reichl, T Frensing
Nature communications 6 (1), 8938, 2015
1642015
A dynamical framework for the all-or-none G1/S transition
AR Barr, FS Heldt, T Zhang, C Bakal, B Novak
Cell systems 2 (1), 27-37, 2016
1262016
Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles
T Frensing, FS Heldt, A Pflugmacher, I Behrendt, I Jordan, D Flockerzi, ...
PloS one 8 (9), e72288, 2013
1222013
Early risk assessment for COVID-19 patients from emergency department data using machine learning
FS Heldt, MP Vizcaychipi, S Peacock, M Cinelli, L McLachlan, F Andreotti, ...
Scientific reports 11 (1), 4200, 2021
1012021
A comprehensive model for the proliferation–quiescence decision in response to endogenous DNA damage in human cells
FS Heldt, AR Barr, S Cooper, C Bakal, B Novák
Proceedings of the National Academy of Sciences 115 (10), 2532-2537, 2018
982018
Multiscale modeling of influenza A virus infection supports the development of direct-acting antivirals
FS Heldt, T Frensing, A Pflugmacher, R Gröpler, B Peschel, U Reichl
PLoS computational biology 9 (11), e1003372, 2013
942013
Modeling the intracellular dynamics of influenza virus replication to understand the control of viral RNA synthesis
FS Heldt, T Frensing, U Reichl
Journal of virology 86 (15), 7806-7817, 2012
942012
Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs
T Laske, FS Heldt, H Hoffmann, T Frensing, U Reichl
Virus Research 213, 90-99, 2016
642016
Real-time RT-qPCR assay for the analysis of human influenza A virus transcription and replication dynamics
D Vester, A Lagoda, D Hoffmann, C Seitz, S Heldt, K Bettenbrock, ...
Journal of virological methods 168 (1-2), 63-71, 2010
592010
Dilution and titration of cell-cycle regulators may control cell size in budding yeast
FS Heldt, R Lunstone, JJ Tyson, B Novák
Plos Computational Biology 14 (10), e1006548, 2018
492018
A single light-responsive sizer can control multiple-fission cycles in Chlamydomonas
FS Heldt, JJ Tyson, FR Cross, B Novák
Current Biology 30 (4), 634-644. e7, 2020
262020
Genome stability during cell proliferation: A systems analysis of the molecular mechanisms controlling progression through the eukaryotic cell cycle
B Novák, FS Heldt, JJ Tyson
Current opinion in systems biology 9, 22-31, 2018
172018
Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection. Nat Commun. 2015; 6: 8938
FS Heldt, SY Kupke, S Dorl, U Reichl, T Frensing
Epub 2015/11/21. https://doi. org/10.1038/ncomms9938 PMID: 26586423, 0
10
Prediction of the onset of cardiovascular diseases from electronic health records using multi-task gated recurrent units
F Andreotti, FS Heldt, B Abu-Jamous, M Li, A Javer, O Carr, S Jovanovic, ...
arXiv preprint arXiv:2007.08491, 2020
92020
Nová k, B.(2016)
AR Barr, FS Heldt, T Zhang, C Bakal
A dynamical framework for the all-or-none G 1, 27-37, 0
9
Reprint of “Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs
T Laske, FS Heldt, H Hoffmann, T Frensing, U Reichl
Virus Research 218, 86-95, 2016
42016
Mathematical models of influenza A virus infection: From intracellular replication to virus growth in cell populations
S Heldt
Otto-von-Guericke Universität Magdeburg, 2015
42015
Community control in cellular protein production: consequences for amino acid starvation
FS Heldt, CA Brackley, C Grebogi, M Thiel
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2015
32015
COVID-19 Patient Outcome Prediction Using Selected Features from Emergency Department Data and Feed-Forward Neural Networks
S Peacock, M Cinelli, FS Heldt, L McLachlan, MP Vizcaychipi, A McCarthy, ...
International Conference on Wireless Mobile Communication and Healthcare …, 2020
2020
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Artikler 1–20