| Inactivation of Rho signaling pathway promotes CNS axon regeneration M Lehmann, A Fournier, I Selles-Navarro, P Dergham, A Sebok, N Leclerc, ... Journal of Neuroscience 19 (17), 7537-7547, 1999 | 744 | 1999 |
| Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions W Siess, KJ Zangl, M Essler, M Bauer, R Brandl, C Corrinth, R Bittman, ... Proceedings of the National Academy of Sciences 96 (12), 6931-6936, 1999 | 640 | 1999 |
| International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature J Chun, EJ Goetzl, T Hla, Y Igarashi, KR Lynch, W Moolenaar, S Pyne, ... Pharmacological reviews 54 (2), 265-269, 2002 | 612 | 2002 |
| Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells. G Tigyi, R Miledi Journal of Biological Chemistry 267 (30), 21360-21367, 1992 | 449 | 1992 |
| Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood T Sano, D Baker, T Virag, A Wada, Y Yatomi, T Kobayashi, Y Igarashi, ... Journal of Biological Chemistry 277 (24), 21197-21206, 2002 | 346 | 2002 |
| Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils N Leitinger, TR Tyner, L Oslund, C Rizza, G Subbanagounder, H Lee, ... Proceedings of the National Academy of Sciences 96 (21), 12010-12015, 1999 | 318 | 1999 |
| Subtype-selective antagonists of lysophosphatidic acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques E Rother, R Brandl, DL Baker, P Goyal, H Gebhard, G Tigyi, W Siess Circulation 108 (6), 741-747, 2003 | 298 | 2003 |
| S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate E Jo, MG Sanna, PJ Gonzalez-Cabrera, S Thangada, G Tigyi, ... Chemistry & biology 12 (6), 703-715, 2005 | 292 | 2005 |
| Direct quantitative analysis of lysophosphatidic acid molecular species by stable isotope dilution electrospray ionization liquid chromatography–mass spectrometry DL Baker, DM Desiderio, DD Miller, B Tolley, GJ Tigyi Analytical biochemistry 292 (2), 287-295, 2001 | 288 | 2001 |
| Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells Y Yatomi, T Ohmori, G Rile, F Kazama, H Okamoto, T Sano, K Satoh, ... Blood, The Journal of the American Society of Hematology 96 (10), 3431-3438, 2000 | 275 | 2000 |
| Lysophosphatidic acid induces neointima formation through PPARγ activation C Zhang, DL Baker, S Yasuda, N Makarova, L Balazs, LR Johnson, ... The Journal of experimental medicine 199 (6), 763-774, 2004 | 264 | 2004 |
| Lysophosphatidic Acid‐Induced Neurite Retraction in PC12 Cells: Control by Phosphoinositide‐Ca2+ Signaling and Rho G Tigyi, DJ Fischer, Á Sebök, C Yang, DL Dyer, R Miledi Journal of neurochemistry 66 (2), 537-548, 1996 | 263 | 1996 |
| Molecular mechanisms of lysophosphatidic acid action G Tigyi, AL Parrill Progress in lipid research 42 (6), 498-526, 2003 | 247 | 2003 |
| FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen … F Tonelli, KG Lim, C Loveridge, J Long, SM Pitson, G Tigyi, R Bittman, ... Cellular signalling 22 (10), 1536-1542, 2010 | 229 | 2010 |
| Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes Z Guo, K Liliom, DJ Fischer, IC Bathurst, LD Tomei, MC Kiefer, G Tigyi Proceedings of the National Academy of Sciences 93 (25), 14367-14372, 1996 | 228 | 1996 |
| Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo H Zhang, X Xu, J Gajewiak, R Tsukahara, Y Fujiwara, J Liu, JI Fells, ... Cancer research 69 (13), 5441-5449, 2009 | 221 | 2009 |
| Plasma lysophosphatidic acid concentration and ovarian cancer DL Baker, P Morrison, B Miller, CA Riely, B Tolley, AM Westermann, ... Jama 287 (23), 3081-3082, 2002 | 219 | 2002 |
| Lysophosphatidic acid possesses dual action in cell proliferation. G Tigyi, DL Dyer, R Miledi Proceedings of the National Academy of Sciences 91 (5), 1908-1912, 1994 | 213 | 1994 |
| Aiming drug discovery at lysophosphatidic acid targets G Tigyi British journal of pharmacology 161 (2), 241-270, 2010 | 211 | 2010 |
| Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis DL Baker, Y Fujiwara, KR Pigg, R Tsukahara, S Kobayashi, H Murofushi, ... Journal of Biological Chemistry 281 (32), 22786-22793, 2006 | 204 | 2006 |