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Christopher J Millard
Christopher J Millard
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Class I HDACs share a common mechanism of regulation by inositol phosphates
CJ Millard, PJ Watson, I Celardo, Y Gordiyenko, SM Cowley, ...
Molecular cell 51 (1), 57-67, 2013
4162013
Insights into the activation mechanism of class I HDAC complexes by inositol phosphates
PJ Watson, CJ Millard, AM Riley, NS Robertson, LC Wright, HY Godage, ...
Nature communications 7 (1), 11262, 2016
2402016
Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells
S Jamaladdin, RDW Kelly, L O’Regan, OM Dovey, GE Hodson, CJ Millard, ...
Proceedings of the National Academy of Sciences 111 (27), 9840-9845, 2014
1852014
Targeting class I histone deacetylases in a “complex” environment
CJ Millard, PJ Watson, L Fairall, JWR Schwabe
Trends in pharmacological sciences 38 (4), 363-377, 2017
1812017
The structure of the core NuRD repression complex provides insights into its interaction with chromatin
CJ Millard, N Varma, A Saleh, K Morris, PJ Watson, AR Bottrill, L Fairall, ...
Elife 5, e13941, 2016
1442016
An evolving understanding of nuclear receptor coregulator proteins
CJ Millard, PJ Watson, L Fairall, JWR Schwabe
Journal of molecular endocrinology 51 (3), T23-T36, 2013
1112013
Recombinant protein expression for structural biology in HEK 293F suspension cells: a novel and accessible approach
N Portolano, PJ Watson, L Fairall, CJ Millard, CP Milano, Y Song, ...
Journal of visualized experiments: JoVE, 51897, 2014
1082014
PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes
KS James, WR John, S MichaeláCowley
Chemical Communications 56 (32), 4476-4479, 2020
1072020
Identification and structural analysis of type I collagen sites in complex with fibronectin fragments
MC Erat, DA Slatter, ED Lowe, CJ Millard, RW Farndale, ID Campbell, ...
Proceedings of the National Academy of Sciences 106 (11), 4195-4200, 2009
1052009
The IDOL–UBE2D complex mediates sterol-dependent degradation of the LDL receptor
L Zhang, L Fairall, BT Goult, AC Calkin, C Hong, CJ Millard, P Tontonoz, ...
Genes & development 25 (12), 1262-1274, 2011
982011
Structural basis of receptor sulfotyrosine recognition by a CC chemokine: the N-terminal region of CCR3 bound to CCL11/eotaxin-1
CJ Millard, JP Ludeman, M Canals, JL Bridgford, MG Hinds, DJ Clayton, ...
Structure 22 (11), 1571-1581, 2014
962014
Tyrosine sulfation influences the chemokine binding selectivity of peptides derived from chemokine receptor CCR3
JZ Zhu, CJ Millard, JP Ludeman, LS Simpson, DJ Clayton, RJ Payne, ...
Biochemistry 50 (9), 1524-1534, 2011
852011
Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting
T Itoh, L Fairall, FW Muskett, CP Milano, PJ Watson, N Arnaudo, A Saleh, ...
Nucleic Acids Research 43 (4), 2033-2044, 2015
702015
The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure
RE Turnbull, L Fairall, A Saleh, E Kelsall, KL Morris, TJ Ragan, CG Savva, ...
Nature communications 11 (1), 3252, 2020
672020
Diverse nucleosome site-selectivity among histone deacetylase complexes
ZA Wang, CJ Millard, CL Lin, JE Gurnett, M Wu, K Lee, L Fairall, ...
Elife 9, e57663, 2020
572020
Towards an understanding of the structure and function of MTA1
CJ Millard, L Fairall, JWR Schwabe
Cancer and Metastasis Reviews 33, 857-867, 2014
552014
A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
T Zhang, G Wei, CJ Millard, R Fischer, R Konietzny, BM Kessler, ...
Nature communications 9 (1), 3798, 2018
532018
The topology of chromatin-binding domains in the NuRD deacetylase complex
CJ Millard, L Fairall, TJ Ragan, CG Savva, JWR Schwabe
Nucleic acids research 48 (22), 12972-12982, 2020
442020
The role of the fibronectin IGD motif in stimulating fibroblast migration
CJ Millard, IR Ellis, AR Pickford, AM Schor, SL Schor, ID Campbell
Journal of Biological Chemistry 282 (49), 35530-35535, 2007
412007
A de novo substitution in BCL11B leads to loss of interaction with transcriptional complexes and craniosynostosis
JAC Goos, WK Vogel, H Mlcochova, CJ Millard, E Esfandiari, WH Selman, ...
Human Molecular Genetics 28 (15), 2501-2513, 2019
322019
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