| A compendium of mutational signatures of environmental agents JE Kucab, X Zou, S Morganella, M Joel, AS Nanda, E Nagy, C Gomez, ... Cell 177 (4), 821-836. e16, 2019 | 600 | 2019 |
| Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study J Staaf, D Glodzik, A Bosch, J Vallon-Christersson, C Reuterswärd, ... Nature medicine 25 (10), 1526-1533, 2019 | 269 | 2019 |
| Evaluating strategies to normalise biological replicates of Western blot data A Degasperi, MR Birtwistle, N Volinsky, J Rauch, W Kolch, ... PloS one 9 (1), e87293, 2014 | 245 | 2014 |
| Mutational signatures: emerging concepts, caveats and clinical applications G Koh, A Degasperi, X Zou, S Momen, S Nik-Zainal Nature Reviews Cancer 21 (10), 619-637, 2021 | 226 | 2021 |
| Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer N Chopra, H Tovey, A Pearson, R Cutts, C Toms, P Proszek, M Hubank, ... Nature communications 11 (1), 2662, 2020 | 226 | 2020 |
| A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies A Degasperi, TD Amarante, J Czarnecki, S Shooter, X Zou, D Glodzik, ... Nature cancer 1 (2), 249-263, 2020 | 225 | 2020 |
| Substitution mutational signatures in whole-genome–sequenced cancers in the UK population A Degasperi, X Zou, T Dias Amarante, A Martinez-Martinez, GCC Koh, ... Science 376 (6591), abl9283, 2022 | 206 | 2022 |
| A practical guide for mutational signature analysis in hematological malignancies F Maura, A Degasperi, F Nadeu, D Leongamornlert, H Davies, L Moore, ... Nature communications 10 (1), 2969, 2019 | 187 | 2019 |
| Bistability in the Rac1, PAK, and RhoA signaling network drives actin cytoskeleton dynamics and cell motility switches KM Byrne, N Monsefi, JC Dawson, A Degasperi, JC Bukowski-Wills, ... Cell systems 2 (1), 38-48, 2016 | 182 | 2016 |
| A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage X Zou, GCC Koh, AS Nanda, A Degasperi, K Urgo, TI Roumeliotis, ... Nature cancer 2 (6), 643-657, 2021 | 136 | 2021 |
| Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes RM Mackenzie, IP Salt, WH Miller, A Logan, HA Ibrahim, A Degasperi, ... Clinical science 124 (6), 403-411, 2013 | 80 | 2013 |
| Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers K Nones, J Johnson, F Newell, AM Patch, H Thorne, SH Kazakoff, ... Annals of Oncology 30 (7), 1071-1079, 2019 | 79 | 2019 |
| Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification B Pellegrino, A Herencia-Ropero, A Llop-Guevara, F Pedretti, ... Cancer research 82 (8), 1646-1657, 2022 | 67 | 2022 |
| Performance of objective functions and optimisation procedures for parameter estimation in system biology models A Degasperi, D Fey, BN Kholodenko NPJ systems biology and applications 3 (1), 20, 2017 | 63 | 2017 |
| Sensitivity analysis of stochastic models of bistable biochemical reactions A Degasperi, S Gilmore International School on Formal Methods for the Design of Computer …, 2008 | 51 | 2008 |
| Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma CL Jones, A Degasperi, V Grandi, TD Amarante, TJ Mitchell, S Nik-Zainal, ... Scientific reports 11 (1), 3962, 2021 | 49 | 2021 |
| Dramatic response of metastatic cutaneous angiosarcoma to an immune checkpoint inhibitor in a patient with xeroderma pigmentosum: whole-genome sequencing aids treatment … S Momen, H Fassihi, HR Davies, C Nikolaou, A Degasperi, CM Stefanato, ... Molecular Case Studies 5 (5), a004408, 2019 | 47 | 2019 |
| Some investigations concerning the CTMC and the ODE model derived from Bio-PEPA F Ciocchetta, A Degasperi, J Hillston, M Calder Electronic Notes in Theoretical Computer Science 229 (1), 145-163, 2009 | 44 | 2009 |
| Targeting the DNA damage response pathways and replication stress in colorectal cancer E Durinikova, NM Reilly, K Buzo, E Mariella, R Chilà, A Lorenzato, ... Clinical Cancer Research 28 (17), 3874-3889, 2022 | 35 | 2022 |
| Basal expression of RAD51 foci predicts olaparib response in patient-derived ovarian cancer xenografts F Guffanti, MF Alvisi, A Anastasia, F Ricci, M Chiappa, A Llop-Guevara, ... British Journal of Cancer 126 (1), 120-128, 2022 | 31 | 2022 |
Muffy CalderProfessor of Computing Science, University of GlasgowVerificeret mail på glasgow.ac.uk