The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology CJ Guerriero, JL Brodsky Physiological reviews 92 (2), 537-576, 2012 | 469 | 2012 |
Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors MD Neal, H Jia, B Eyer, M Good, CJ Guerriero, CP Sodhi, A Afrazi, ... PloS one 8 (6), e65779, 2013 | 136 | 2013 |
Differential involvement of endocytic compartments in the biosynthetic traffic of apical proteins KO Cresawn, BA Potter, A Oztan, CJ Guerriero, G Ihrke, JR Goldenring, ... The EMBO journal 26 (16), 3737-3748, 2007 | 131 | 2007 |
Chaperoning endoplasmic reticulum–associated degradation (ERAD) and protein conformational diseases PG Needham, CJ Guerriero, JL Brodsky Cold Spring Harbor perspectives in biology 11 (8), a033928, 2019 | 122 | 2019 |
Membrane traffic and turnover in TRP-ML1–deficient cells: a revised model for mucolipidosis type IV pathogenesis MT Miedel, Y Rbaibi, CJ Guerriero, G Colletti, KM Weixel, OA Weisz, ... The Journal of experimental medicine 205 (6), 1477-1490, 2008 | 109 | 2008 |
Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase CJ Guerriero, KF Weiberth, JL Brodsky Journal of Biological Chemistry 288 (25), 18506-18520, 2013 | 96 | 2013 |
Chemical induction of Hsp70 reduces α-synuclein aggregation in neuroglioma cells K Kilpatrick, JA Novoa, T Hancock, CJ Guerriero, P Wipf, JL Brodsky, ... ACS chemical biology 8 (7), 1460-1468, 2013 | 93 | 2013 |
Phosphatidylinositol 5-kinase stimulates apical biosynthetic delivery via an Arp2/3-dependent mechanism CJ Guerriero, KM Weixel, JR Bruns, OA Weisz Journal of Biological Chemistry 281 (22), 15376-15384, 2006 | 65 | 2006 |
OCRL1 function in renal epithelial membrane traffic S Cui, CJ Guerriero, CM Szalinski, CL Kinlough, RP Hughey, OA Weisz American Journal of Physiology-Renal Physiology 298 (2), F335-F345, 2010 | 63 | 2010 |
N-WASP inhibitor wiskostatin nonselectively perturbs membrane transport by decreasing cellular ATP levels CJ Guerriero, OA Weisz American Journal of Physiology-Cell Physiology 292 (4), C1562-C1566, 2007 | 61 | 2007 |
Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substrates CJ Guerriero, KR Reutter, AA Augustine, GM Preston, KF Weiberth, ... Molecular biology of the cell 28 (15), 2076-2090, 2017 | 43 | 2017 |
Combined chemical–genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma AJ Sabnis, CJ Guerriero, V Olivas, A Sayana, J Shue, J Flanagan, ... Proceedings of the National Academy of Sciences 113 (32), 9015-9020, 2016 | 42 | 2016 |
Phosphatidylinositol 4-phosphate 5-kinase reduces cell surface expression of the epithelial sodium channel (ENaC) in cultured collecting duct cells KM Weixel, RS Edinger, L Kester, CJ Guerriero, H Wang, L Fang, ... Journal of Biological Chemistry 282 (50), 36534-36542, 2007 | 40 | 2007 |
ESCRT regulates surface expression of the Kir2. 1 potassium channel AR Kolb, PG Needham, C Rothenberg, CJ Guerriero, PA Welling, ... Molecular biology of the cell 25 (2), 276-289, 2014 | 39 | 2014 |
Membrane protein properties revealed through data-rich electrostatics calculations FV Marcoline, N Bethel, CJ Guerriero, JL Brodsky, M Grabe Structure 23 (8), 1526-1537, 2015 | 38 | 2015 |
Differential sorting and Golgi export requirements for raft-associated and raft-independent apical proteins along the biosynthetic pathway CJ Guerriero, Y Lai, OA Weisz Journal of Biological Chemistry 283 (26), 18040-18047, 2008 | 38 | 2008 |
Substrate insolubility dictates Hsp104-dependent endoplasmic-reticulum-associated degradation GM Preston, CJ Guerriero, MB Metzger, S Michaelis, JL Brodsky Molecular cell 70 (2), 242-253. e6, 2018 | 36 | 2018 |
Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells S Sannino, CJ Guerriero, AJ Sabnis, DB Stolz, CT Wallace, P Wipf, ... Journal of Cell Science 131 (17), jcs217760, 2018 | 24 | 2018 |
Hsp104 facilitates the endoplasmic‐reticulum–associated degradation of disease‐associated and aggregation‐prone substrates LM Doonan, CJ Guerriero, GM Preston, TM Buck, N Khazanov, EA Fisher, ... Protein Science 28 (7), 1290-1306, 2019 | 23 | 2019 |
PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells CM Szalinski, CJ Guerriero, WG Ruiz, BE Docter, Y Rbaibi, ... PloS one 8 (1), e53790, 2013 | 16 | 2013 |