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Christopher J. Guerriero
Christopher J. Guerriero
Research Assistant Professor, University of Pittsburgh, Department of Biological Sciences
Verificeret mail på pitt.edu
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The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology
CJ Guerriero, JL Brodsky
Physiological reviews 92 (2), 537-576, 2012
4692012
Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors
MD Neal, H Jia, B Eyer, M Good, CJ Guerriero, CP Sodhi, A Afrazi, ...
PloS one 8 (6), e65779, 2013
1362013
Differential involvement of endocytic compartments in the biosynthetic traffic of apical proteins
KO Cresawn, BA Potter, A Oztan, CJ Guerriero, G Ihrke, JR Goldenring, ...
The EMBO journal 26 (16), 3737-3748, 2007
1312007
Chaperoning endoplasmic reticulum–associated degradation (ERAD) and protein conformational diseases
PG Needham, CJ Guerriero, JL Brodsky
Cold Spring Harbor perspectives in biology 11 (8), a033928, 2019
1222019
Membrane traffic and turnover in TRP-ML1–deficient cells: a revised model for mucolipidosis type IV pathogenesis
MT Miedel, Y Rbaibi, CJ Guerriero, G Colletti, KM Weixel, OA Weisz, ...
The Journal of experimental medicine 205 (6), 1477-1490, 2008
1092008
Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase
CJ Guerriero, KF Weiberth, JL Brodsky
Journal of Biological Chemistry 288 (25), 18506-18520, 2013
962013
Chemical induction of Hsp70 reduces α-synuclein aggregation in neuroglioma cells
K Kilpatrick, JA Novoa, T Hancock, CJ Guerriero, P Wipf, JL Brodsky, ...
ACS chemical biology 8 (7), 1460-1468, 2013
932013
Phosphatidylinositol 5-kinase stimulates apical biosynthetic delivery via an Arp2/3-dependent mechanism
CJ Guerriero, KM Weixel, JR Bruns, OA Weisz
Journal of Biological Chemistry 281 (22), 15376-15384, 2006
652006
OCRL1 function in renal epithelial membrane traffic
S Cui, CJ Guerriero, CM Szalinski, CL Kinlough, RP Hughey, OA Weisz
American Journal of Physiology-Renal Physiology 298 (2), F335-F345, 2010
632010
N-WASP inhibitor wiskostatin nonselectively perturbs membrane transport by decreasing cellular ATP levels
CJ Guerriero, OA Weisz
American Journal of Physiology-Cell Physiology 292 (4), C1562-C1566, 2007
612007
Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substrates
CJ Guerriero, KR Reutter, AA Augustine, GM Preston, KF Weiberth, ...
Molecular biology of the cell 28 (15), 2076-2090, 2017
432017
Combined chemical–genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma
AJ Sabnis, CJ Guerriero, V Olivas, A Sayana, J Shue, J Flanagan, ...
Proceedings of the National Academy of Sciences 113 (32), 9015-9020, 2016
422016
Phosphatidylinositol 4-phosphate 5-kinase reduces cell surface expression of the epithelial sodium channel (ENaC) in cultured collecting duct cells
KM Weixel, RS Edinger, L Kester, CJ Guerriero, H Wang, L Fang, ...
Journal of Biological Chemistry 282 (50), 36534-36542, 2007
402007
ESCRT regulates surface expression of the Kir2. 1 potassium channel
AR Kolb, PG Needham, C Rothenberg, CJ Guerriero, PA Welling, ...
Molecular biology of the cell 25 (2), 276-289, 2014
392014
Membrane protein properties revealed through data-rich electrostatics calculations
FV Marcoline, N Bethel, CJ Guerriero, JL Brodsky, M Grabe
Structure 23 (8), 1526-1537, 2015
382015
Differential sorting and Golgi export requirements for raft-associated and raft-independent apical proteins along the biosynthetic pathway
CJ Guerriero, Y Lai, OA Weisz
Journal of Biological Chemistry 283 (26), 18040-18047, 2008
382008
Substrate insolubility dictates Hsp104-dependent endoplasmic-reticulum-associated degradation
GM Preston, CJ Guerriero, MB Metzger, S Michaelis, JL Brodsky
Molecular cell 70 (2), 242-253. e6, 2018
362018
Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells
S Sannino, CJ Guerriero, AJ Sabnis, DB Stolz, CT Wallace, P Wipf, ...
Journal of Cell Science 131 (17), jcs217760, 2018
242018
Hsp104 facilitates the endoplasmic‐reticulum–associated degradation of disease‐associated and aggregation‐prone substrates
LM Doonan, CJ Guerriero, GM Preston, TM Buck, N Khazanov, EA Fisher, ...
Protein Science 28 (7), 1290-1306, 2019
232019
PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells
CM Szalinski, CJ Guerriero, WG Ruiz, BE Docter, Y Rbaibi, ...
PloS one 8 (1), e53790, 2013
162013
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Artikler 1–20