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Improved vectors and genome-wide libraries for CRISPR screening NE Sanjana, O Shalem, F Zhang Nature methods 11 (8), 783-784, 2014 | 5345 | 2014 |
High-throughput functional genomics using CRISPR–Cas9 O Shalem, NE Sanjana, F Zhang Nature Reviews Genetics 16 (5), 299-311, 2015 | 1440 | 2015 |
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening J Joung, S Konermann, JS Gootenberg, OO Abudayyeh, RJ Platt, ... Nature protocols 12 (4), 828-863, 2017 | 1275 | 2017 |
Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5′ sites S Schwartz, MR Mumbach, M Jovanovic, T Wang, K Maciag, GG Bushkin, ... Cell reports 8 (1), 284-296, 2014 | 1240 | 2014 |
Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis S Chen, NE Sanjana, K Zheng, O Shalem, K Lee, X Shi, DA Scott, J Song, ... Cell 160 (6), 1246-1260, 2015 | 1120 | 2015 |
A transcription activator-like effector toolbox for genome engineering NE Sanjana, L Cong, Y Zhou, MM Cunniff, G Feng, F Zhang Nature protocols 7 (1), 171-192, 2012 | 1013 | 2012 |
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ... Nature 527 (7577), 192-197, 2015 | 984 | 2015 |
Identification of essential genes for cancer immunotherapy SJ Patel, NE Sanjana, RJ Kishton, A Eidizadeh, SK Vodnala, M Cam, ... Nature 548 (7669), 537-542, 2017 | 890 | 2017 |
CRISPR-Cas component systems, methods and compositions for sequence manipulation F Zhang US Patent 8,795,965, 2014 | 695 | 2014 |
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains F Zhang, L Cong, RJ Platt, NE Sanjana, RAN Fei US Patent 8,993,233, 2015 | 607 | 2015 |
Identification of required host factors for SARS-CoV-2 infection in human cells Z Daniloski, TX Jordan, HH Wessels, DA Hoagland, S Kasela, M Legut, ... Cell 184 (1), 92-105. e16, 2021 | 566 | 2021 |
A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks O Parnas, M Jovanovic, TM Eisenhaure, RH Herbst, A Dixit, CJ Ye, ... Cell 162 (3), 675-686, 2015 | 545 | 2015 |
Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells EP Mimitou, A Cheng, A Montalbano, S Hao, M Stoeckius, M Legut, ... Nature methods 16 (5), 409-412, 2019 | 474 | 2019 |
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 468 | 2010 |
Hypoxia as a therapy for mitochondrial disease IH Jain, L Zazzeron, R Goli, K Alexa, S Schatzman-Bone, H Dhillon, ... Science 352 (6281), 54-61, 2016 | 458 | 2016 |
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Massively parallel Cas13 screens reveal principles for guide RNA design HH Wessels, A Méndez-Mancilla, X Guo, M Legut, Z Daniloski, ... Nature biotechnology 38 (6), 722-727, 2020 | 356 | 2020 |
CRISPR in cancer biology and therapy A Katti, BJ Diaz, CM Caragine, NE Sanjana, LE Dow Nature Reviews Cancer 22 (5), 259-279, 2022 | 333 | 2022 |
Mice with Shank3 mutations associated with ASD and schizophrenia display both shared and distinct defects Y Zhou, T Kaiser, P Monteiro, X Zhang, MS Van der Goes, D Wang, ... Neuron 89 (1), 147-162, 2016 | 333 | 2016 |