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Hallie Blevins
Hallie Blevins
Virginia Commonwealth University
Verificeret mail på vcuhealth.org
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The NLRP3 inflammasome pathway: a review of mechanisms and inhibitors for the treatment of inflammatory diseases
HM Blevins, Y Xu, S Biby, S Zhang
Frontiers in aging neuroscience 14, 879021, 2022
2822022
A novel inhibitor targeting NLRP3 inflammasome reduces neuropathology and improves cognitive function in Alzheimer’s disease transgenic mice
R Kuwar, A Rolfe, L Di, H Blevins, Y Xu, X Sun, GS Bloom, S Zhang, ...
Journal of Alzheimer's Disease 82 (4), 1769-1783, 2021
632021
Discovery of second-generation NLRP3 inflammasome inhibitors: Design, synthesis, and biological characterization
Y Jiang, L He, J Green, H Blevins, C Guo, SH Patel, MS Halquist, ...
Journal of medicinal chemistry 62 (21), 9718-9731, 2019
522019
CPT1A-mediated fatty acid oxidation confers cancer cell resistance to immune-mediated cytolytic killing
Z Liu, W Liu, W Wang, Y Ma, Y Wang, DL Drum, J Cai, H Blevins, E Lee, ...
Proceedings of the National Academy of Sciences 120 (39), e2302878120, 2023
302023
Discovery of carbon-11 labeled sulfonamide derivative: a PET tracer for imaging brain NLRP3 inflammasome
Y Xu, Y Xu, H Blevins, Y Lan, Y Liu, G Yuan, R Striar, JS Zagaroli, ...
Bioorganic & medicinal chemistry letters 34, 127777, 2021
182021
Development of sulfonamide-based NLRP3 inhibitors: Further modifications and optimization through structure-activity relationship studies
Y Xu, Y Xu, H Blevins, C Guo, S Biby, XY Wang, C Wang, S Zhang
European journal of medicinal chemistry 238, 114468, 2022
152022
The NLRP3 inflammasome pathway: A review of mechanisms and inhibitors for the treatment of inflammatory diseases. Front Aging Neurosci 2022; 14: 879021
HM Blevins, Y Xu, S Biby, S Zhang
Trends Pharmacol Sci 43 (8), 653-68, 2022
112022
The NLRP3 inflammasome pathway: a review of mechanisms and inhibitors for the treatment of inflammatory diseases. Front Aging Neurosci 14: 879021
HM Blevins, Y Xu, S Biby, S Zhang
92022
Characterization of an extracellular polyhydroxyalkanoate depolymerase from streptomyces sp. SFB5A
HM Blevins, MKD Blue, BD Cobbs, TA Ricotilli, SL Kyler, CT Shuey, ...
Journal of Bioremediation & Biodegradation 9 (05), 2018
92018
Development of bivalent compounds as potential neuroprotectants for Alzheimer’s disease
L He, Y Jiang, J Green, H Blevins, S Zhang
Bioorganic & medicinal chemistry letters 29 (15), 1957-1961, 2019
42019
Mechanistic Insights of Sulfonamide‐Based NLRP3 Inhibitors for the Treatment of Neurodegenerative Diseases
H Blevins, Y Xu, S Biby, S Zhang
The FASEB Journal 36, 2022
22022
Structural insights of sulfonamide-based NLRP3 inflammasome inhibitors: design, synthesis, and biological characterization
Y Xu, M Scipioni, H Blevins, S Zhang
Medicinal Chemistry Research 30, 473-482, 2021
22021
Development of NLRP3 Inflammasome Inhibitors
HM Blevins
2022
Development of NLRP3 inhibitors for Alzheimer's disease
S Zhang, Y Xu, H Blevins
Alzheimer's & Dementia 17, e049271, 2021
2021
Mechanistic insights of novel NLRP3 inhibitors as potential AD therapeutics: Nonhuman/Target identification and validation studies: Inflammation and innate immunity
J Green, H Blevins, Y Xu, S Zhang
Alzheimer's & Dementia 16, e037215, 2020
2020
Mechanistic insights of novel NLRP3 inhibitors as potential AD therapeutics
J Green, H Blevins, Y Xu, S Zhang
2020 Alzheimer's Association International Conference, 2020
2020
Characterization of polyhydroxyalkanoate enzymatic degradation products by mass spectrometry
H Blevins, S Baron
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018
2018
Characterization of an extracellular polyhydroxyalkanoate depolymerase from Streptomyces sp. SFB5A
S Baron, HM Blevins, BD Cobbs, M Blue, TA Ricotilli, SL Kyler, CT Shuey, ...
2018
Journal of Bioremediation & Biodegradation
HM Blevins, D M’Kala, BD Cobbs, TA Ricotilli, SL Kyler, CT Shuey, ...
2018
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Artikler 1–19