Følg
Andrew Varley
Titel
Citeret af
Citeret af
År
Establishing a Role for Bacterial Cellulose in Environmental Interactions: Lessons Learned from Diverse Biofilm-Producing Proteobacteria
RV Augimeri, AJ Varley, JL Strap
Frontiers in microbiology 6, 1282, 2015
1452015
Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing
B Li, RS Manan, SQ Liang, A Gordon, A Jiang, A Varley, G Gao, R Langer, ...
Nature biotechnology 41 (10), 1410-1415, 2023
1412023
Clinical delivery of circular RNA: lessons learned from RNA drug development
TL Young, KC Wang, AJ Varley, B Li
Advanced Drug Delivery Reviews 197, 114826, 2023
652023
Accelerating ionizable lipid discovery for mRNA delivery using machine learning and combinatorial chemistry
B Li, IO Raji, AGR Gordon, L Sun, TM Raimondo, FA Oladimeji, AY Jiang, ...
Nature Materials 23 (7), 1002-1008, 2024
382024
Combinatorial design of ionizable lipid nanoparticles for muscle-selective mRNA delivery with minimized off-target effects
J Chen, Y Xu, M Zhou, S Xu, AJ Varley, A Golubovic, RXZ Lu, KC Wang, ...
Proceedings of the National Academy of Sciences 120 (50), e2309472120, 2023
332023
AGILE platform: a deep learning powered approach to accelerate LNP development for mRNA delivery
Y Xu, S Ma, H Cui, J Chen, S Xu, F Gong, A Golubovic, M Zhou, KC Wang, ...
Nature communications 15 (1), 6305, 2024
322024
Tumor‐tailored ionizable lipid nanoparticles facilitate IL‐12 circular RNA delivery for enhanced lung cancer immunotherapy
S Xu, Y Xu, NC Solek, J Chen, F Gong, AJ Varley, A Golubovic, A Pan, ...
Advanced Materials 36 (29), 2400307, 2024
252024
Chemical strategies for strand selection in short-interfering RNAs
AJ Varley, JP Desaulniers
RSC advances 11 (4), 2415-2426, 2021
182021
Effects of chemical modifications on siRNA strand selection in mammalian cells
AJ Varley, ML Hammill, L Salim, JP Desaulniers
nucleic acid therapeutics 30 (4), 229-236, 2020
122020
Synthesis and evaluation of neutral phosphate triester backbone-modified siRNAs
K Tsubaki, ML Hammill, AJ Varley, M Kitamura, T Okauchi, ...
ACS Medicinal Chemistry Letters 11 (7), 1457-1462, 2020
122020
SiRNAs with neutral phosphate triester hydrocarbon tails exhibit carrier-free gene-silencing activity
ML Hammill, K Tsubaki, L Salim, AJ Varley, I Giorgees, M Kitamura, ...
ACS Medicinal Chemistry Letters 13 (4), 695-700, 2022
92022
Building siRNAs with cubes: synthesis and evaluation of cubane‐modified siRNAs
ML Hammill, L Salim, K Tsubaki, AJ Varley, M Kitamura, T Okauchi, ...
ChemBioChem 22 (20), 2981-2985, 2021
52021
The transcription factor, FixK, plays a central role in carbon source metabolism and cellulose synthesis in Komagataeibacter species
AJ Varley
University of Ontario Institute of Technology (Canada), 2017
12017
Utilizing the Ethylene-releasing Compound, 2-Chloroethylphosphonic Acid, as a Tool to Study Ethylene Response in Bacteria
RV Augimeri, AJ Varley, JL Strap
Journal of Visualized Experiments: JoVE, 54682, 2016
12016
A Reverse Transcription Nucleic-Acid-Based Barcoding System for In Vivo Measurement of Lipid Nanoparticle mRNA Delivery
KC Wang, TL Young, J Chen, SN Tsai, Y Xu, AJ Varley, NC Solek, F Gong, ...
ACS Bio & Med Chem Au, 2025
2025
Zwitterionic Hydrogels: From Synthetic Design to Biomedical Applications
L Gao, A Varley, H Gao, B Li, X Li
Langmuir, 2025
2025
Suggested searches
M Watson, D Sabirova, MC Hardy, Y Pan, DCJ Carpentier, H Yates, ...
Perspective, 2024
2024
Tumor‐Tailored Ionizable Lipid Nanoparticles Facilitate IL‐12 Circular RNA Delivery for Enhanced Lung Cancer Immunotherapy (Adv. Mater. 29/2024)
S Xu, Y Xu, NC Solek, J Chen, F Gong, AJ Varley, A Golubovic, A Pan, ...
Advanced Materials 36 (29), 2470228, 2024
2024
Synthesis of 5’-fluorophosphate-modified short-interfering RNAs
A Varley, JP Desaulniers
Nucleosides, Nucleotides & Nucleic Acids 42 (5), 358-370, 2023
2023
Development and characterization of chemical modifications for siRNA strand selection
AJ Varley
2021
Systemet kan ikke foretage handlingen nu. Prøv igen senere.
Artikler 1–20