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Emma Lefrancais
Emma Lefrancais
IPBS CNRS
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The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors
E Lefrançais, G Ortiz-Muñoz, A Caudrillier, B Mallavia, F Liu, DM Sayah, ...
Nature 544 (7648), 105-109, 2017
12262017
IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G
E Lefrançais, S Roga, V Gautier, A Gonzalez-de-Peredo, B Monsarrat, ...
Proceedings of the National Academy of Sciences 109 (5), 1673-1678, 2012
7152012
Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: in situ analysis using a novel Il-33–LacZ gene …
M Pichery, E Mirey, P Mercier, E Lefrancais, A Dujardin, N Ortega, ...
The Journal of Immunology 188 (7), 3488-3495, 2012
5562012
Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury
E Lefrançais, B Mallavia, H Zhuo, CS Calfee, MR Looney
JCI insight 3 (3), e98178, 2018
4372018
Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells
E Lefrançais, A Duval, E Mirey, S Roga, E Espinosa, C Cayrol, JP Girard
Proceedings of the National Academy of Sciences 111 (43), 15502-15507, 2014
4292014
Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice
MAK Sedhom, M Pichery, JR Murdoch, B Foligné, N Ortega, S Normand, ...
Gut 62 (12), 1714-1723, 2013
2372013
Extracellular DNA, neutrophil extracellular traps, and inflammasome activation in severe asthma
ME Lachowicz-Scroggins, EM Dunican, AR Charbit, W Raymond, ...
American journal of respiratory and critical care medicine 199 (9), 1076-1085, 2019
2312019
2012 ECS-ECN JUNIOR REVIEW AWARD–Mechanisms of IL-33 processing and secretion: differences and similarities between IL-1 family members
E Lefrançais, C Cayrol
European cytokine network 23 (4), 120-127, 2012
1492012
Mitochondrial DNA stimulates TLR9-dependent neutrophil extracellular trap formation in primary graft dysfunction
B Mallavia, F Liu, E Lefrançais, SJ Cleary, N Kwaan, JJ Tian, M Magnen, ...
American journal of respiratory cell and molecular biology 62 (3), 364-372, 2020
942020
Platelet biogenesis in the lung circulation
E Lefrançais, MR Looney
Physiology 34 (6), 392-401, 2019
882019
Aspirin reduces lipopolysaccharide-induced pulmonary inflammation in human models of ARDS
U Hamid, A Krasnodembskaya, M Fitzgerald, M Shyamsundar, ...
Thorax 72 (11), 971-980, 2017
782017
LPS-induced lung platelet recruitment occurs independently from neutrophils, PSGL-1, and P-selectin
SJ Cleary, C Hobbs, RT Amison, S Arnold, BG O’Shaughnessy, ...
American journal of respiratory cell and molecular biology 61 (2), 232-243, 2019
642019
Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation
G Ortiz-Muñoz, AY Michelle, E Lefrançais, B Mallavia, C Valet, JJ Tian, ...
The Journal of clinical investigation 130 (4), 2041-2053, 2020
492020
Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa
K Santoni, D Pericat, L Gorse, J Buyck, M Pinilla, L Prouvensier, ...
PLoS pathogens 18 (7), e1010305, 2022
382022
ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection
D Corral, A Charton, MZ Krauss, E Blanquart, F Levillain, E Lefrançais, ...
Cell Reports 39 (3), 2022
272022
Neutralizing extracellular histones in acute respiratory distress syndrome. A new role for an endogenous pathway
E Lefrançais, MR Looney
American Journal of Respiratory and Critical Care Medicine 196 (2), 122-124, 2017
202017
Occurrence and role of lung megakaryocytes in infection and inflammation
L Gelon, L Fromont, E Lefrançais
Frontiers in Immunology 13, 1029223, 2022
192022
Method for increasing granulocyte number in a patient by administering superactive IL-33 fragments
JP Girard, C Cayrol-Girard, E Lefrancais
US Patent 9,611,307, 2017
102017
TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation
P Schmitt, A Duval, M Camus, E Lefrançais, S Roga, C Dedieu, N Ortega, ...
Journal of Experimental Medicine 221 (6), e20231236, 2024
62024
Metabolic control of type 2 innate lymphoid cells plasticity toward protective type 1-like cells during Mycobacterium tuberculosis infection
D Corral, A Charton, MZ Krauss, E Blanquart, F Levillain, E Lefrançais, ...
bioRxiv, 2021.01. 19.427257, 2021
52021
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Artikler 1–20