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Tory Hagen
Tory Hagen
Professor of Biochemistry and Biophysics, Oregon State University
Verificeret mail på orst.edu
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Oxidants, antioxidants, and the degenerative diseases of aging.
BN Ames, MK Shigenaga, TM Hagen
Proceedings of the National Academy of Sciences 90 (17), 7915-7922, 1993
96761993
Oxidative damage and mitochondrial decay in aging.
MK Shigenaga, TM Hagen, BN Ames
Proceedings of the National Academy of Sciences 91 (23), 10771-10778, 1994
28511994
Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential
KP Shay, RF Moreau, EJ Smith, AR Smith, TM Hagen
Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (10), 1149-1160, 2009
13012009
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
JH Suh, SV Shenvi, BM Dixon, H Liu, AK Jaiswal, RM Liu, TM Hagen
Proceedings of the National Academy of Sciences 101 (10), 3381-3386, 2004
9332004
Selective fluorescent imaging of superoxide in vivo using ethidium-based probes
KM Robinson, MS Janes, M Pehar, JS Monette, MF Ross, TM Hagen, ...
Proceedings of the National Academy of Sciences 103 (41), 15038-15043, 2006
9052006
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-l-carnitine and/or R-α-lipoic acid
J Liu, E Head, AM Gharib, W Yuan, RT Ingersoll, TM Hagen, CW Cotman, ...
Proceedings of the National Academy of Sciences 99 (4), 2356-2361, 2002
7342002
Chronically and acutely exercised rats: biomarkers of oxidative stress and endogenous antioxidants
J Liu, HC Yeo, E Overvik-Douki, T Hagen, SJ Doniger, DW Chu, ...
Journal of applied physiology 89 (1), 21-28, 2000
6922000
Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress
AR Smith, SV Shenvi, M Widlansky, JH Suh, TM Hagen
Current medicinal chemistry 11 (9), 1135-1146, 2004
6772004
Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase
TM Hagen, DL Yowe, JC Bartholomew, CM Wehr, KL Do, JY Park, ...
Proceedings of the National Academy of Sciences 94 (7), 3064-3069, 1997
5711997
Mitochondrial decay in aging
BN Ames, MK Shigenaga, TM Hagen
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1271 (1), 165-170, 1995
5461995
Feeding acetyl-l-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress
TM Hagen, J Liu, J Lykkesfeldt, CM Wehr, RT Ingersoll, V Vinarsky, ...
Proceedings of the National Academy of sciences 99 (4), 1870-1875, 2002
4902002
Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma.
TM Hagen, S Huang, J Curnutte, P Fowler, V Martinez, CM Wehr, ...
Proceedings of the National Academy of Sciences 91 (26), 12808-12812, 1994
4051994
Acetyl-l-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity
TM Hagen, RT Ingersoll, CM Wehr, J Lykkesfeldt, V Vinarsky, ...
Proceedings of the National Academy of Sciences 95 (16), 9562-9566, 1998
3581998
Age‐associated increases in oxidative stress and antioxidant enzyme activities in cardiac interfibrillar mitochondria: implications for the mitochondrial theory of aging
S Judge, YM Jang, A Smith, T Hagen, C Leeuwenburgh
The FASEB journal 19 (3), 1-21, 2005
3542005
α-Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway
WJ Zhang, H Wei, T Hagen, B Frei
Proceedings of the National Academy of Sciences 104 (10), 4077-4082, 2007
3362007
Glutathione metabolism during aging and in Alzheimer disease
H Liu, H Wang, S Shenvi, TM Hagen, RUIM LIU
Annals of the New York Academy of Sciences 1019 (1), 346-349, 2004
3302004
(R)‐α‐Lipoic acid‐supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate
TM Hagen, RT Ingersoll, J Lykkesfeldt, J LIU, CM WEHR, V VINARSKY, ...
The FASEB journal 13 (2), 411-418, 1999
3181999
Exogenous glutathione protects intestinal epithelial cells from oxidative injury.
LH Lash, TM Hagen, DP Jones
Proceedings of the National Academy of Sciences 83 (13), 4641-4645, 1986
2641986
Oxidative damage increases with age in a canine model of human brain aging
E Head, J Liu, TM Hagen, BA Muggenburg, NW Milgram, BN Ames, ...
Journal of neurochemistry 82 (2), 375-381, 2002
2632002
Is α‐lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity
K Petersen Shay, RF Moreau, EJ Smith, TM Hagen
IUBMB life 60 (6), 362-367, 2008
2372008
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Artikler 1–20