A comparison of reference-based algorithms for correcting cell-type heterogeneity in Epigenome-Wide Association Studies AE Teschendorff, CE Breeze, SC Zheng, S Beck BMC bioinformatics 18, 1-14, 2017 | 401 | 2017 |
Correlation of an epigenetic mitotic clock with cancer risk Z Yang, A Wong, D Kuh, DS Paul, VK Rakyan, RD Leslie, SC Zheng, ... Genome biology 17, 1-18, 2016 | 275 | 2016 |
Identification of differentially methylated cell types in epigenome-wide association studies SC Zheng, CE Breeze, S Beck, AE Teschendorff Nature methods 15 (12), 1059-1066, 2018 | 235 | 2018 |
Cell-type deconvolution in epigenome-wide association studies: a review and recommendations AE Teschendorff, SC Zheng Epigenomics 9 (5), 757-768, 2017 | 189 | 2017 |
recount3: summaries and queries for large-scale RNA-seq expression and splicing C Wilks, SC Zheng, FY Chen, R Charles, B Solomon, JP Ling, EL Imada, ... Genome biology 22 (1), 1-40, 2021 | 187 | 2021 |
A novel cell-type deconvolution algorithm reveals substantial contamination by immune cells in saliva, buccal and cervix SC Zheng, AP Webster, D Dong, A Feber, DG Graham, R Sullivan, ... Epigenomics 10 (7), 925-940, 2018 | 145 | 2018 |
Epigenetic drift, epigenetic clocks and cancer risk SC Zheng, M Widschwendter, AE Teschendorff Epigenomics 8 (5), 705-719, 2016 | 127 | 2016 |
Universal prediction of cell-cycle position using transfer learning SC Zheng, G Stein-O’Brien, JJ Augustin, J Slosberg, GA Carosso, B Winer, ... Genome Biology 23 (1), 1-27, 2022 | 81 | 2022 |
Correcting for cell-type heterogeneity in epigenome-wide association studies: revisiting previous analyses SC Zheng, S Beck, AE Jaffe, DC Koestler, KD Hansen, AE Houseman, ... Nature methods 14 (3), 216-217, 2017 | 70 | 2017 |
Cell and tissue type independent age-associated DNA methylation changes are not rare but common T Zhu, SC Zheng, DS Paul, S Horvath, AE Teschendorff Aging (Albany NY) 10 (11), 3541, 2018 | 59 | 2018 |
EpiDISH web server: epigenetic dissection of intra-sample-heterogeneity with online GUI SC Zheng, CE Breeze, S Beck, D Dong, T Zhu, L Ma, W Ye, G Zhang, ... Bioinformatics 36 (6), 1950-1951, 2020 | 54 | 2020 |
Limb development genes underlie variation in human fingerprint patterns J Li, JD Glover, H Zhang, M Peng, J Tan, CB Mallick, D Hou, Y Yang, ... Cell 185 (1), 95-112. e18, 2022 | 53 | 2022 |
A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes C You, S Wu, SC Zheng, T Zhu, H Jing, K Flagg, G Wang, L Jin, S Wang, ... Nature communications 11 (1), 4779, 2020 | 48 | 2020 |
Pumping the brakes on RNA velocity by understanding and interpreting RNA velocity estimates SC Zheng, G Stein-O’Brien, L Boukas, LA Goff, KD Hansen Genome Biology 24 (1), 246, 2023 | 41 | 2023 |
The multi-omic landscape of transcription factor inactivation in cancer AE Teschendorff, SC Zheng, A Feber, Z Yang, S Beck, M Widschwendter Genome medicine 8 (1), 1-15, 2016 | 34 | 2016 |
A metagenomic approach to dissect the genetic composition of enterotypes in Han Chinese and two Muslim groups J Li, R Fu, Y Yang, HP Horz, Y Guan, Y Lu, H Lou, L Tian, S Zheng, H Liu, ... Systematic and applied microbiology 41 (1), 1-12, 2018 | 29 | 2018 |
A meta-analysis of immune-cell fractions at high resolution reveals novel associations with common phenotypes and health outcomes Q Luo, VB Dwaraka, Q Chen, H Tong, T Zhu, K Seale, JM Raffaele, ... Genome Medicine 15 (1), 59, 2023 | 24 | 2023 |
ebGSEA: An improved gene set enrichment analysis method for epigenome-wide-association studies D Dong, Y Tian, SC Zheng, AE Teschendorff Bioinformatics 35 (18), 3514-3516, 2019 | 21 | 2019 |
DNA methylation signatures in vaginal fluid samples for detection of cervical and endometrial cancer K Doufekas, SC Zheng, S Ghazali, M Wong, Y Mohamed, A Jones, ... Int J Gynecol Cancer 1, 2016 | 19 | 2016 |