Targeting inflammation in cancer prevention and therapy J Todoric, L Antonucci, M Karin Cancer prevention research 9 (12), 895-905, 2016 | 400 | 2016 |
Histone deacetylase and Cullin3–REN KCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation G Canettieri, L Di Marcotullio, A Greco, S Coni, L Antonucci, P Infante, ... Nature cell biology 12 (2), 132-142, 2010 | 390 | 2010 |
NRF2 as a regulator of cell metabolism and inflammation in cancer F He, L Antonucci, M Karin Carcinogenesis 41 (4), 405-416, 2020 | 275 | 2020 |
Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress L Antonucci, JB Fagman, JY Kim, J Todoric, I Gukovsky, M Mackey, ... Proceedings of the National Academy of Sciences 112 (45), E6166-E6174, 2015 | 275 | 2015 |
Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling D Dhar, L Antonucci, H Nakagawa, JY Kim, E Glitzner, S Caruso, ... Cancer cell 33 (6), 1061-1077. e6, 2018 | 205 | 2018 |
Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production E Sanchez-Lopez, Z Zhong, A Stubelius, SR Sweeney, LM Booshehri, ... Cell metabolism 29 (6), 1350-1362. e7, 2019 | 200 | 2019 |
Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis H Su, F Yang, R Fu, X Li, R French, E Mose, X Pu, B Trinh, A Kumar, J Liu, ... Cancer Cell, 2021 | 140 | 2021 |
Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas J Todoric, L Antonucci, G Di Caro, N Li, X Wu, NK Lytle, D Dhar, ... Cancer cell 32 (6), 824-839. e8, 2017 | 129 | 2017 |
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress D Mazzà, P Infante, V Colicchia, A Greco, R Alfonsi, M Siler, L Antonucci, ... Cell Death & Differentiation 20 (12), 1688-1697, 2013 | 102 | 2013 |
NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly F He, L Antonucci, S Yamachika, Z Zhang, K Taniguchi, A Umemura, ... Journal of hepatology 72 (6), 1182-1195, 2020 | 99 | 2020 |
BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages A Rosati, A Basile, R D’Auria, M d’Avenia, M De Marco, A Falco, M Festa, ... Nature communications 6 (1), 1-11, 2015 | 99 | 2015 |
Non-canonical Hedgehog/AMPK-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth D D’Amico, L Antonucci, L Di Magno, S Coni, G Sdruscia, A Macone, ... Developmental cell 35 (1), 21-35, 2015 | 90 | 2015 |
Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation Y Zhou, IN Bastian, MD Long, M Dow, W Li, T Liu, RK Ngu, L Antonucci, ... Proceedings of the National Academy of Sciences 118 (8), 2021 | 84 | 2021 |
Gli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy S Coni, L Antonucci, D D'Amico, L Di Magno, P Infante, E De Smaele, ... PLoS One 8 (6), e65718, 2013 | 80 | 2013 |
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1 G Canettieri, S Coni, M Della Guardia, V Nocerino, L Antonucci, ... Proceedings of the National Academy of Sciences 106 (5), 1445-1450, 2009 | 80 | 2009 |
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells E Miele, A Po, F Begalli, L Antonucci, A Mastronuzzi, CE Marras, A Carai, ... BMC cancer 17 (1), 1-12, 2017 | 69 | 2017 |
Recent insights into the pathogenic mechanism of pancreatitis: role of acinar cell organelle disorders AS Gukovskaya, FS Gorelick, GE Groblewski, OA Mareninova, A Lugea, ... Pancreas 48 (4), 459, 2019 | 65 | 2019 |
The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint L Di Magno, A Basile, S Coni, S Manni, G Sdruscia, D D'Amico, ... Oncotarget 7 (8), 9538, 2016 | 51 | 2016 |
NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leukemia E Sanchez-Lopez, EM Ghia, L Antonucci, N Sharma, LZ Rassenti, J Xu, ... Cell Death & Differentiation 27 (7), 2206-2216, 2020 | 44 | 2020 |
Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation L Antonucci, L Di Magno, D D'Amico, S Manni, SM Serrao, F Di Pastena, ... International journal of oncology 54 (2), 505-514, 2019 | 31 | 2019 |