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Nicholas Hess
Nicholas Hess
University of Wisconsin-Madison School of Medicine and Public Health
Verificeret mail på wisc.edu
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TLR10 is a negative regulator of both MyD88-dependent and-independent TLR signaling
S Jiang, X Li, NJ Hess, Y Guan, RI Tapping
The Journal of Immunology 196 (9), 3834-3841, 2016
1552016
TLR10 is a B cell intrinsic suppressor of adaptive immune responses
NJ Hess, S Jiang, X Li, Y Guan, RI Tapping
The Journal of Immunology 198 (2), 699-707, 2017
522017
TLR10 suppresses the activation and differentiation of monocytes with effects on DC-mediated adaptive immune responses
NJ Hess, C Felicelli, J Grage, RI Tapping
Journal of Leucocyte Biology 101 (5), 1245-1252, 2017
512017
GVHD pathogenesis, prevention and treatment: lessons from humanized mouse transplant models
NJ Hess, ME Brown, CM Capitini
Frontiers in immunology 12, 723544, 2021
402021
Different human immune lineage compositions are generated in non-conditioned NBSGW mice depending on HSPC source
NJ Hess, PN Lindner, J Vazquez, S Grindel, AW Hudson, AK Stanic, ...
Frontiers in Immunology 11, 573406, 2020
312020
Early T cell activation metrics predict graft-versus-host disease in a humanized mouse model of hematopoietic stem cell transplantation
NJ Hess, AW Hudson, P Hematti, JE Gumperz
The Journal of Immunology 205 (1), 272-281, 2020
222020
Inflammatory CD4/CD8 double-positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology
NJ Hess, DP Turicek, J Riendeau, SJ McIlwain, E Contreras Guzman, ...
Science Advances 9 (12), eadf0567, 2023
192023
CXCR4 allows T cell acute lymphoblastic leukemia to escape from JAK1/2 and BCL2 inhibition through CNS infiltration
KL Walker, SP Rinella, NJ Hess, DP Turicek, SA Kabakov, F Zhu, ...
Leukemia & lymphoma 62 (5), 1167-1177, 2021
152021
iNKT cells coordinate immune pathways to enable engraftment in nonconditioned hosts
NJ Hess, NS Bharadwaj, EA Bobeck, CE McDougal, S Ma, JD Sauer, ...
Life Science Alliance 4 (7), 2021
102021
Exosomes, MDSCs and Tregs: A new frontier for GVHD prevention and treatment
NJ Hess, JA Kink, P Hematti
Frontiers in Immunology 14, 1143381, 2023
42023
TIM-3 blockade enhances ex vivo stimulated allogeneic NK cell therapy for relapsed murine neuroblastoma after hematopoietic cell transplant
AE Quamine, NR Mohrdieck, CA King, AA Griggs, JM Kline, MM Cho, ...
bioRxiv, 2024.07. 09.602731, 2024
22024
Griddient: a microfluidic array to generate reconfigurable gradients on-demand for spatial biology applications
C Sanchez-de-Diego, M Virumbrales-Muñoz, B Hermes, TD Juang, ...
Communications Biology 6 (1), 925, 2023
22023
TLR10 (CD290) is a Regulator of Immune responses in human plasmacytoid dendritic cells
P Deb, S Singh, E Kalyoussef, NJ Hess, RI Tapping, P Fitzgerald-Bocarsly
The Journal of Immunology 213 (5), 577-587, 2024
12024
Combination fedratinib and venetoclax has activity against human B-ALL with high FLT3 expression
SP Rinella, HC Bell, NJ Hess, NM Hoang, TT Nguyen, DP Turicek, L Shi, ...
bioRxiv, 2023.06. 07.544058, 2024
12024
Combinatorial fedratinib and Venetoclax treatment is effective on human B cell acute lymphoblastic leukemia with high FLT3 expression
SP Rinella, HC Bell, DP Turicek, L Shi, NM Hoang, L Rui, NJ Hess, ...
bioRxiv, 2023.06. 07.544058, 2023
12023
Interim analysis of T cell specific predictive biomarkers of graft-vs-host disease and relapse following post transplant cyclophosphamide prophylaxis
NJ Hess, KV Nadiminti, P Hematti, CM Capitini
2022 Tandem Meetings| Transplantation & Cellular Therapy Meetings of ASTCT …, 2022
12022
1107 Luminescent reporter assays for ADCP and ADCC characterization of immunotherapies targeting primary effector cells
NJ Hess, JK Gilden, J Mitchell, D Garvin, R Moravec, P Stecha, F Fan, ...
Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024
2024
Use of Toll-Like Receptor 4 Agonists to Treat Inflammation and Tissue Injury
P Hematti, J Kink, C Capitini, M Forsberg, H Nicholas, Z Rosenkrans, ...
US Patent App. 18/624,848, 2024
2024
Abstract A071: Pancreas organoid immune co-culture system identifies immunomodulators in pancreas adenocarcinoma
JD Ebben, D Turicek, MS Hossan, A Stram, E Lin, N Hess, Z Mayhew, ...
Molecular Cancer Therapeutics 22 (12_Supplement), A071-A071, 2023
2023
382 TIM-3 blockade combined with adoptive therapy of ex vivo activated NK cells after allogeneic hematopoietic stem cell transplant reduces progression of relapsed murine …
A Quamine, NR Mohrdieck, CA King, AA Griggs, KE Tippins, PD Bates, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
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