Rob van der Kant

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Nikolaos LourosAssistant Professor, UT Soutwestern Medical CenterVerificeret mail på utsouthwestern.edu
Emiel MichielsPostdoc, VIB-KULeuven UniversityVerificeret mail på kuleuven.be
Bert HoubenPhD Researcher, VIB KULeuvenVerificeret mail på kuleuven.be
Tobias LangenbergVIBVerificeret mail på vib.be
Vriend GDirector BIPS Mindoro PhilippinesVerificeret mail på radboudumc.nl
Chris UlensKU LeuvenVerificeret mail på kuleuven.be
Daniel SeeligerBoehringer IngelheimVerificeret mail på boehringer-ingelheim.com
Maxime SiemonsThe Janssen Pharmaceutical Companies of Johnson & JohnsonVerificeret mail på its.jnj.com
Johan NeytsProfessor of Virology @KU Leuven; Co-Founder AstriVax Therapeutics & VirusbankPlatformVerificeret mail på rega.kuleuven.be
Guy BormansProfessor KU LeuvenVerificeret mail på kuleuven.be
Lorena Itati IbañezInstituto de Química Física de los Materiales, Medio Ambiente y Energía (INQUIMAE)Verificeret mail på qi.fcen.uba.ar
Vignir IsbergSenior Manager, NovonesisVerificeret mail på vignir.org
David E. GloriamDepartment of Drug Design and Pharmacology, University of CopenhagenVerificeret mail på sund.ku.dk
Kang LiDepartment of Mathmatical Sciences, University of CopenhagenVerificeret mail på math.ku.dk
Patrik VerstrekenVIB Center for Brain & Disease Research & KU Leuven, Department of NeurosciencesVerificeret mail på kuleuven.vib.be
Natalia V. GounkoUTSWVerificeret mail på utsouthwestern.edu
Shelli McAlpineVisiting Professor, University of California, IrvineVerificeret mail på uci.edu
Ramon Duran-RomañaPost-doctoral researcher at VIB Switch LabVerificeret mail på kuleuven.be
Bassem HassanScientific Director and Team Leader, Paris Brain InstituteVerificeret mail på icm-institute.org
Mathieu BollenProfessor of Molecular Cell Biology, University of Leuven, BelgiumVerificeret mail på kuleuven.be

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Rob van der Kant

Postdoctoral Researcher KULeuven

Verificeret mail på kuleuven.vib.be

Protein Aggregation Structural Bioinformatics


Titel Sortér efter henvisninger Sortér efter årstal Sortér efter titel	Citeret af Citeret af	År
Prediction and reduction of the aggregation of monoclonal antibodies R van der Kant, AR Karow-Zwick, J Van Durme, M Blech, R Gallardo, ... Journal of molecular biology 429 (8), 1244-1261, 2017	166	2017
GPCRDB: an information system for G protein-coupled receptors V Isberg, B Vroling, R van der Kant, K Li, G Vriend, D Gloriam Nucleic acids research 42 (D1), D422-D425, 2014	155	2014
Hsp90 mediates membrane deformation and exosome release E Lauwers, YC Wang, R Gallardo, R Van der Kant, E Michiels, J Swerts, ... Molecular cell 71 (5), 689-702. e9, 2018	153	2018
Solubis: a webserver to reduce protein aggregation through mutation J Van Durme, G De Baets, R Van Der Kant, M Ramakers, A Ganesan, ... Protein Engineering, Design and Selection 29 (8), 285-289, 2016	73	2016
Structural hot spots for the solubility of globular proteins A Ganesan, A Siekierska, J Beerten, M Brams, J Van Durme, G De Baets, ... Nature communications 7 (1), 10816, 2016	72	2016
Post-translational control of the temporal dynamics of transcription factor activity regulates neurogenesis XJ Quan, L Yuan, L Tiberi, A Claeys, N De Geest, J Yan, R Van Der Kant, ... Cell 164 (3), 460-475, 2016	67	2016
Thermodynamic and evolutionary coupling between the native and amyloid state of globular proteins T Langenberg, R Gallardo, R van der Kant, N Louros, E Michiels, ... Cell reports 31 (2), 2020	44	2020
Alpha-bulges in G protein-coupled receptors R Van der Kant, G Vriend International journal of molecular sciences 15 (5), 7841-7864, 2014	44	2014
Defective Sec61α1 underlies a novel cause of autosomal dominant severe congenital neutropenia E Van Nieuwenhove, JS Barber, J Neumann, E Smeets, M Willemsen, ... Journal of Allergy and Clinical Immunology 146 (5), 1180-1193, 2020	43	2020
Reverse engineering synthetic antiviral amyloids E Michiels, K Roose, R Gallardo, L Khodaparast, L Khodaparast, ... Nature communications 11 (1), 2832, 2020	39	2020
Autonomous aggregation suppression by acidic residues explains why chaperones favour basic residues B Houben, E Michiels, M Ramakers, K Konstantoulea, N Louros, ... The EMBO journal 39 (11), e102864, 2020	35	2020
Thermodynamic analysis of amyloid fibril structures reveals a common framework for stability in amyloid polymorphs R van der Kant, N Louros, J Schymkowitz, F Rousseau Structure 30 (8), 1178-1189. e3, 2022	33*	2022
Solubis: optimize your protein G De Baets, J Van Durme, R van der Kant, J Schymkowitz, F Rousseau Bioinformatics 31 (15), 2580-2582, 2015	29	2015
Adaption of human antibody λ and κ light chain architectures to CDR repertoires R van der Kant, J Bauer, AR Karow-Zwick, S Kube, P Garidel, M Blech, ... Protein Engineering, Design and Selection 32 (3), 109-127, 2019	17	2019
StAmP-DB: a platform for structures of polymorphic amyloid fibril cores N Louros, R Van Der Kant, J Schymkowitz, F Rousseau Bioinformatics 38 (9), 2636-2638, 2022	14	2022
SolubiS: Optimizing protein solubility by minimal point mutations R van der Kant, J van Durme, F Rousseau, J Schymkowitz Protein Misfolding Diseases: Methods and Protocols, 317-333, 2019	12	2019
The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis N Guthertz, R Van Der Kant, RM Martinez, Y Xu, CH Trinh, BI Iorga, ... Proceedings of the National Academy of Sciences 119 (22), e2200468119, 2022	11	2022
Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein K Janssen, F Claes, D Van de Velde, VL Wehbi, B Houben, Y Lampi, ... Proceedings of the National Academy of Sciences 120 (9), e2214921120, 2023	6	2023
Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V F Claes, S Rudyak, AS Laird, N Louros, J Beerten, M Debulpaep, ... Protein Engineering, Design and Selection 32 (10), 443-457, 2019	6	2019
De novodesign of high-affinity single-domain antibodies R van der Kant, Z Zhang, I Marković, D Vizarraga, T Garcia, K Maragkou, ...	4	2024

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