| PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data K Wang, M Li, D Hadley, R Liu, J Glessner, SFA Grant, H Hakonarson, ... Genome research 17 (11), 1665-1674, 2007 | 2063 | 2007 |
| A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain Y Ding, JH Sohn, MG Kawczynski, H Trivedi, R Harnish, NW Jenkins, ... Radiology 290 (2), 456-464, 2019 | 678 | 2019 |
| Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration W Chen, D Stambolian, AO Edwards, KE Branham, M Othman, ... Proceedings of the National Academy of Sciences 107 (16), 7401-7406, 2010 | 620 | 2010 |
| Systematic integration of biomedical knowledge prioritizes drugs for repurposing DS Himmelstein, A Lizee, C Hessler, L Brueggeman, SL Chen, D Hadley, ... Elife 6, e26726, 2017 | 550 | 2017 |
| Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes M Bucan, BS Abrahams, K Wang, JT Glessner, EI Herman, LI Sonnenblick, ... PLoS genetics 5 (6), e1000536, 2009 | 499 | 2009 |
| Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder J Elia, JT Glessner, K Wang, N Takahashi, CJ Shtir, D Hadley, ... Nature genetics 44 (1), 78-84, 2012 | 432 | 2012 |
| Copy-number disorders are a common cause of congenital kidney malformations. Source: American journal of human genetics (0002-9297) 91 (2012); 987-997 S Sanna-Cherchi, K Kiryluk, KE Burgess, M Bodria, MG Sampson, ... American journal of human genetics 91 (2012), 987-997, 2012 | 258 | 2012 |
| Common variants at 6q22 and 17q21 are associated with intracranial volume Nature genetics 44 (5), 539-544, 2012 | 171 | 2012 |
| Common variants at 12q15 and 12q24 are associated with infant head circumference HR Taal, B St Pourcain, E Thiering, S Das, DO Mook-Kanamori, ... Nature genetics 44 (5), 532-538, 2012 | 162 | 2012 |
| Development and validation of an electronic health record–based machine learning model to estimate delirium risk in newly hospitalized patients without known cognitive impairment A Wong, AT Young, AS Liang, R Gonzales, VC Douglas, D Hadley JAMA network open 1 (4), e181018-e181018, 2018 | 148 | 2018 |
| The impact of COVID-19 on African American communities in the United States E Cyrus, R Clarke, D Hadley, Z Bursac, MJ Trepka, JG Dévieux, U Bagci, ... Health Equity 4 (1), 476-483, 2020 | 101 | 2020 |
| Relating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational research B Chen, M Sirota, H Fan-Minogue, D Hadley, AJ Butte BMC medical genomics 8, 1-10, 2015 | 98 | 2015 |
| Are minor alleles more likely to be risk alleles? T Kido, W Sikora-Wohlfeld, M Kawashima, S Kikuchi, N Kamatani, ... BMC medical genomics 11, 1-11, 2018 | 97 | 2018 |
| Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index A Hinney, M Kesselmeier, S Jall, AL Volckmar, M Föcker, J Antel, IM Heid, ... Molecular psychiatry 22 (2), 192-201, 2017 | 91 | 2017 |
| Identification of rare recurrent copy number variants in high-risk autism families and their prevalence in a large ASD population N Matsunami, D Hadley, CH Hensel, GB Christensen, C Kim, E Frackelton, ... PloS one 8 (1), e52239, 2013 | 89 | 2013 |
| Association between high-risk disease loci and response to anti–vascular endothelial growth factor treatment for wet age-related macular degeneration A Orlin, D Hadley, W Chang, AC Ho, G Brown, RS Kaiser, CD Regillo, ... Retina 32 (1), 4-9, 2012 | 88 | 2012 |
| Rare copy number variants in over 100,000 European ancestry subjects reveal multiple disease associations YR Li, JT Glessner, BP Coe, J Li, M Mohebnasab, X Chang, J Connolly, ... Nature communications 11 (1), 255, 2020 | 80 | 2020 |
| The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism D Hadley, Z Wu, C Kao, A Kini, A Mohamed-Hadley, K Thomas, ... Nature communications 5 (1), 4074, 2014 | 74 | 2014 |
| Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk JD Hoffman, RE Graff, NC Emami, CG Tai, MN Passarelli, D Hu, ... PLoS genetics 13 (3), e1006690, 2017 | 71 | 2017 |
| Association between mitochondrial DNA haplogroup variation and autism spectrum disorders D Chalkia, LN Singh, J Leipzig, M Lvova, O Derbeneva, A Lakatos, ... JAMA psychiatry 74 (11), 1161-1168, 2017 | 70 | 2017 |
Hakon HakonarsonDirector, Center for Applied Genomics, CHOP, UPENNVerificeret mail på email.chop.edu
