Regulated virulence controls the ability of a pathogen to compete with the gut microbiota N Kamada, YG Kim, HP Sham, BA Vallance, JL Puente, EC Martens, ... Science 336 (6086), 1325-1329, 2012 | 749 | 2012 |
Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa KSB Bergstrom, V Kissoon-Singh, DL Gibson, C Ma, M Montero, ... PLoS pathogens 6 (5), e1000902, 2010 | 696 | 2010 |
Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens LA Knodler, SM Crowley, HP Sham, H Yang, M Wrande, C Ma, RK Ernst, ... Cell host & microbe 16 (2), 249-256, 2014 | 466 | 2014 |
Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice AS Lee, DL Gibson, Y Zhang, HP Sham, BA Vallance, JP Dutz Diabetologia 53, 741-748, 2010 | 146 | 2010 |
A Novel Mouse Model of Campylobacter jejuni Gastroenteritis Reveals Key Pro-inflammatory and Tissue Protective Roles for Toll-like Receptor Signaling during … M Stahl, J Ries, J Vermeulen, H Yang, HP Sham, SM Crowley, ... PLoS pathogens 10 (7), e1004264, 2014 | 139 | 2014 |
DNBS/TNBS colitis models: providing insights into inflammatory bowel disease and effects of dietary fat V Morampudi, G Bhinder, X Wu, C Dai, HP Sham, BA Vallance, ... Journal of visualized experiments: JoVE, 51297, 2014 | 129 | 2014 |
The goblet cell-derived mediator RELM-β drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis V Morampudi, U Dalwadi, G Bhinder, HP Sham, SK Gill, J Chan, ... Mucosal immunology 9 (5), 1218-1233, 2016 | 117 | 2016 |
Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-κB and p38 mitogen-activated protein kinase activation HP Sham, SR Shames, MA Croxen, C Ma, JM Chan, MA Khan, ... Infection and immunity 79 (9), 3552-3562, 2011 | 113 | 2011 |
Goblet Cell Derived RELM-β Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation KSB Bergstrom, V Morampudi, JM Chan, G Bhinder, J Lau, H Yang, C Ma, ... PLoS pathogens 11 (8), e1005108, 2015 | 109 | 2015 |
Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation RE Abdulnour, HP Sham, DN Douda, RA Colas, J Dalli, Y Bai, X Ai, ... Mucosal immunology 9 (5), 1278-1287, 2016 | 101 | 2016 |
SIGIRR, a negative regulator of TLR/IL-1R signalling promotes Microbiota dependent resistance to colonization by enteric bacterial pathogens HP Sham, EYS Yu, MF Gulen, G Bhinder, M Stahl, JM Chan, L Brewster, ... PLoS pathogens 9 (8), e1003539, 2013 | 97 | 2013 |
Active vitamin D (1,25-dihydroxyvitamin D3) increases host susceptibility to Citrobacter rodentium by suppressing mucosal Th17 responses NR Ryz, SJ Patterson, Y Zhang, C Ma, T Huang, G Bhinder, X Wu, J Chan, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 303 (12 …, 2012 | 97 | 2012 |
The Citrobacter rodentium mouse model: studying pathogen and host contributions to infectious colitis G Bhinder, HP Sham, JM Chan, V Morampudi, K Jacobson, BA Vallance Journal of visualized experiments: JoVE, 50222, 2013 | 93 | 2013 |
Interleukin-11 reduces TLR4-induced colitis in TLR2-deficient mice and restores intestinal STAT3 signaling DL Gibson, M Montero, MJ Ropeleski, KSB Bergstrom, C Ma, S Ghosh, ... Gastroenterology 139 (4), 1277-1288, 2010 | 92 | 2010 |
The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling SR Shames, W Deng, JA Guttman, CL De Hoog, Y Li, PR Hardwidge, ... Cellular microbiology 12 (9), 1322-1339, 2010 | 92 | 2010 |
Intestinal epithelium-specific MyD88 signaling impacts host susceptibility to infectious colitis by promoting protective goblet cell and antimicrobial responses G Bhinder, M Stahl, HP Sham, SM Crowley, V Morampudi, U Dalwadi, ... Infection and immunity 82 (9), 3753-3763, 2014 | 91 | 2014 |
15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 induce NF-κB regulators in bacterial pneumonia HP Sham, KH Walker, REE Abdulnour, N Krishnamoorthy, DN Douda, ... The Journal of Immunology 200 (8), 2757-2766, 2018 | 76 | 2018 |
Metalloprotease NleC suppresses host NF-κB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction A Hodgson, EM Wier, K Fu, X Sun, H Yu, W Zheng, HP Sham, K Johnson, ... PLoS pathogens 11 (3), e1004705, 2015 | 70 | 2015 |
Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apcmin mice H Xiao, W Yin, MA Khan, MF Gulen, H Zhou, HP Sham, K Jacobson, ... Gastroenterology 139 (2), 574-585, 2010 | 66 | 2010 |
Innate host responses to enteric bacterial pathogens: a balancing act between resistance and tolerance KS Bergstrom, HP Sham, M Zarepour, BA Vallance Cellular microbiology 14 (4), 475-484, 2012 | 64 | 2012 |