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Anthony Segal
Anthony Segal
Professor of Medicine, UCL
Verificeret mail på ucl.ac.uk - Startside
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How neutrophils kill microbes
AW Segal
Annu. Rev. Immunol. 23 (1), 197-223, 2005
24662005
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor
EO Glocker, D Kotlarz, K Boztug, EM Gertz, AA Schäffer, F Noyan, M Perro, ...
New England Journal of Medicine 361 (21), 2033-2045, 2009
17362009
Killing activity of neutrophils is mediated through activation of proteases by K+ flux
EP Reeves, H Lu, HL Jacobs, CGM Messina, S Bolsover, G Gabella, ...
Nature 416 (6878), 291-297, 2002
14502002
Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1
A Abo, E Pick, A Hall, N Totty, CG Teahan, AW Segal
Nature 353 (6345), 668-670, 1991
12161991
Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency
F Altare, A Durandy, D Lammas, JF Emile, S Lamhamedi, F Le Deist, ...
Science 280 (5368), 1432-1435, 1998
10741998
The biochemical basis of the NADPH oxidase of phagocytes
AW Segal, A Abo
Trends in biochemical sciences 18 (2), 43-47, 1993
8041993
The NADPH oxidase of professional phagocytes—prototype of the NOX electron transport chain systems
AR Cross, AW Segal
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1657 (1), 1-22, 2004
6362004
Elemental diet as primary treatment of acute Crohn's disease: a controlled trial.
C O'moráin, AW Segal, AJ Levi
Br Med J (Clin Res Ed) 288 (6434), 1859-1862, 1984
5851984
Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease
AM Smith, FZ Rahman, BH Hayee, SJ Graham, DJB Marks, GW Sewell, ...
Journal of Experimental Medicine 206 (9), 1883-1897, 2009
5422009
Interaction of Rac with p67phox and Regulation pf Phagocytic NADPH Oxidase Activity
D Diekmann, A Abo, C Johnston, AW Segal, A Hall
Science 265 (5171), 531-533, 1994
5331994
Defective acute inflammation in Crohn's disease: a clinical investigation
DJB Marks, MWN Harbord, R MacAllister, FZ Rahman, J Young, ...
The Lancet 367 (9511), 668-678, 2006
5292006
Mutations in the X-linked and autosomal recessive forms of chronic granulomatous disease
D Roos, M de Boer, F Kuribayashi, C Meischl, RS Weening, AW Segal, ...
Blood 87 (5), 1663-1681, 1996
4951996
The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH
AW Segal, M Geisow, R Garcia, A Harper, R Miller
Nature 290 (5805), 406-409, 1981
4951981
Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription.
KH In, K Asano, D Beier, J Grobholz, PW Finn, EK Silverman, ...
The Journal of clinical investigation 99 (5), 1130-1137, 1997
4771997
Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G
J Tkalcevic, M Novelli, M Phylactides, JP Iredale, AW Segal, J Roes
Immunity 12 (2), 201-210, 2000
4762000
Indium-111-labeled autologous leukocytes in man
ML Thakur, JP Lavender, RN Arnot, DJ Silvester, AW Segal
Journal of Nuclear medicine 18 (10), 1014-1021, 1977
4661977
Novel cytochrome b system in phagocytic vacuoles of human granulocytes
AW Segal, OTG JONES
Nature 276 (5687), 515-517, 1978
4631978
Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes
AW Segal, I West, F Wientjes, JHA Nugent, AJ Chavan, B Haley, ...
Biochemical Journal 284 (3), 781-788, 1992
4221992
p40phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains
FB Wientjes, JJ Hsuan, NF Totty, AW Segal
Biochemical Journal 296 (3), 557-561, 1993
3991993
Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease
KY Hui, H Fernandez-Hernandez, J Hu, A Schaffner, N Pankratz, NY Hsu, ...
Science translational medicine 10 (423), eaai7795, 2018
3892018
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