| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13848* | 2021 |
| Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 M Baker, IR Mackenzie, SM Pickering-Brown, J Gass, R Rademakers, ... Nature 442 (7105), 916-919, 2006 | 2333 | 2006 |
| Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease D Morgan, DM Diamond, PE Gottschall, KE Ugen, C Dickey, J Hardy, ... Nature 408 (6815), 982-985, 2000 | 2167 | 2000 |
| The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins CA Dickey, A Kamal, K Lundgren, N Klosak, RM Bailey, J Dunmore, P Ash, ... The Journal of clinical investigation 117 (3), 648-658, 2007 | 798 | 2007 |
| Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43 YJ Zhang, Y Xu, CA Dickey, E Buratti, F Baralle, R Bailey, ... Journal of Neuroscience 27 (39), 10530-10534, 2007 | 447 | 2007 |
| Hsp90-Tau complex reveals molecular basis for specificity in chaperone action GE Karagöz, AMS Duarte, E Akoury, H Ippel, J Biernat, TM Luengo, ... Cell 156 (5), 963-974, 2014 | 353 | 2014 |
| C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins YJ Zhang, TF Gendron, JC Grima, H Sasaguri, K Jansen-West, YF Xu, ... Nature neuroscience 19 (5), 668-677, 2016 | 345 | 2016 |
| Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo EE Congdon, JW Wu, N Myeku, YH Figueroa, M Herman, PS Marinec, ... Autophagy 8 (4), 609-622, 2012 | 341 | 2012 |
| Accelerated neurodegeneration through chaperone-mediated oligomerization of tau LJ Blair, BA Nordhues, SE Hill, KM Scaglione, JC O’Leary, SN Fontaine, ... The Journal of clinical investigation 123 (10), 4158-4169, 2013 | 340 | 2013 |
| LPS-induced inflammation exacerbates phospho-tau pathology in rTg4510 mice DC Lee, J Rizer, MLB Selenica, P Reid, C Kraft, A Johnson, L Blair, ... Journal of neuroinflammation 7, 1-16, 2010 | 334 | 2010 |
| FKBP51 and FKBP52 in signaling and disease CL Storer, CA Dickey, MD Galigniana, T Rein, MB Cox Trends in Endocrinology & Metabolism 22 (12), 481-490, 2011 | 321 | 2011 |
| Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein+ presenilin-1 transgenic mice CA Dickey, JF Loring, J Montgomery, MN Gordon, PS Eastman, D Morgan Journal of Neuroscience 23 (12), 5219-5226, 2003 | 306 | 2003 |
| Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho-and caspase-3-cleaved tau species CA Dickey, M Yue, WL Lin, DW Dickson, JH Dunmore, WC Lee, C Zehr, ... Journal of Neuroscience 26 (26), 6985-6996, 2006 | 299 | 2006 |
| Chemical manipulation of hsp70 ATPase activity regulates tau stability UK Jinwal, Y Miyata, J Koren, JR Jones, JH Trotter, L Chang, J O'Leary, ... Journal of neuroscience 29 (39), 12079-12088, 2009 | 282 | 2009 |
| Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ... Journal of Neuroscience 33 (22), 9498-9507, 2013 | 281 | 2013 |
| Akt and CHIP coregulate tau degradation through coordinated interactions CA Dickey, J Koren, YJ Zhang, Y Xu, UK Jinwal, MJ Birnbaum, B Monks, ... Proceedings of the National Academy of Sciences 105 (9), 3622-3627, 2008 | 249 | 2008 |
| The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ... Journal of Neuroscience 30 (2), 591-599, 2010 | 241 | 2010 |
| DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins SN Fontaine, D Zheng, JJ Sabbagh, MD Martin, D Chaput, A Darling, ... The EMBO journal 35 (14), 1537-1549, 2016 | 229 | 2016 |
| Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones A Rousaki, Y Miyata, UK Jinwal, CA Dickey, JE Gestwicki, ERP Zuiderweg Journal of molecular biology 411 (3), 614-632, 2011 | 216 | 2011 |
| Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ... Molecular neurodegeneration 5, 1-11, 2010 | 208 | 2010 |
Laura BlairUniversity of South FloridaVerificeret mail på usf.edu