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Fatima Pardo-Avila
Fatima Pardo-Avila
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De novo design of potent and selective mimics of IL-2 and IL-15
DA Silva, S Yu, UY Ulge, JB Spangler, KM Jude, C Labão-Almeida, LR Ali, ...
Nature 565 (7738), 186-191, 2019
4912019
Comprehensive computational design of ordered peptide macrocycles
P Hosseinzadeh, G Bhardwaj, VK Mulligan, MD Shortridge, TW Craven, ...
Science 358 (6369), 1461-1466, 2017
2012017
Millisecond dynamics of RNA polymerase II translocation at atomic resolution
DA Silva, DR Weiss, F Pardo Avila, LT Da, M Levitt, D Wang, X Huang
Proceedings of the National Academy of Sciences 111 (21), 7665-7670, 2014
1662014
Bridge helix bending promotes RNA polymerase II backtracking through a critical and conserved threonine residue
LT Da, F Pardo-Avila, L Xu, DA Silva, L Zhang, X Gao, D Wang, X Huang
Nature communications 7 (1), 11244, 2016
972016
The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding
R Kudva, P Tian, F Pardo-Avila, M Carroni, RB Best, HD Bernstein, ...
Elife 7, e36326, 2018
822018
Elucidation of the dynamics of transcription elongation by RNA polymerase II using kinetic network models
L Zhang, F Pardo-Avila, IC Unarta, PPH Cheung, G Wang, D Wang, ...
Accounts of chemical research 49 (4), 687-694, 2016
662016
A two-state model for the dynamics of the pyrophosphate ion release in bacterial RNA polymerase
LT Da, F Pardo Avila, D Wang, X Huang
PLoS computational biology 9 (4), e1003020, 2013
652013
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
P Hosseinzadeh, PR Watson, TW Craven, X Li, S Rettie, F Pardo-Avila, ...
Nature Communications 12 (1), 3384, 2021
632021
Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature
ME O’Sullivan, F Poitevin, RG Sierra, C Gati, EH Dao, Y Rao, F Aksit, ...
Nucleic acids research 46 (18), 9793-9804, 2018
282018
Structural model of RNA polymerase II elongation complex with complete transcription bubble reveals NTP entry routes
L Zhang, DA Silva, F Pardo-Avila, D Wang, X Huang
PLoS computational biology 11 (7), e1004354, 2015
232015
Structure of the 30S ribosomal decoding complex at ambient temperature
EH Dao, F Poitevin, RG Sierra, C Gati, Y Rao, HI Ciftci, F Akşit, A McGurk, ...
Rna 24 (12), 1667-1676, 2018
202018
8-Oxo-guanine DNA damage induces transcription errors by escaping two distinct fidelity control checkpoints of RNA polymerase II
KA Konovalov, F Pardo-Avila, CKM Tse, J Oh, D Wang, X Huang
Journal of Biological Chemistry 294 (13), 4924-4933, 2019
152019
Structural, thermodynamic and catalytic characterization of an ancestral triosephosphate isomerase reveal early evolutionary coupling between monomer association and function
M Schulte‐Sasse, F Pardo‐Ávila, NO Pulido‐Mayoral, A Vázquez‐Lobo, ...
The FEBS Journal 286 (5), 882-900, 2019
102019
Constructing kinetic network models to elucidate mechanisms of functional conformational changes of enzymes and their recognition with ligands
L Zhang, H Jiang, FK Sheong, F Pardo-Avila, PPH Cheung, X Huang
Methods in Enzymology 578, 343-371, 2016
82016
Theoretical investigations on elucidating fundamental mechanisms of catalysis and dynamics involved in transcription by RNA polymerase
F Pardo-Avila, LT Da, Y Wang, X Huang
Journal of Theoretical and Computational Chemistry 12 (08), 1341005, 2013
62013
Probing interplays between human XBP1u translational arrest peptide and 80S ribosome
F Di Palma, S Decherchi, F Pardo-Avila, S Succi, M Levitt, G von Heijne, ...
Journal of chemical theory and computation 18 (3), 1905-1914, 2021
52021
PDBCleanV2: A Python Library for Generating Consistent Structure Datasets
F Pardo-Avila, L Weiner, P Cabral, NC Corsepius, F Poitevin, M Levitt
bioRxiv, 2025.02. 14.638326, 2025
2025
Single-residue effects on the behavior of a nascent polypeptide chain inside the ribosome exit tunnel
F Pardo-Avila, R Kudva, M Levitt, G Von Heijne
bioRxiv, 2024
2024
Dynamics of the transcription elongation process of RNA polymerase elucidated at atomic resolution by molecular dynamics and Markov state models
FA Pardo Avila
2015
Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature
EO Mary, F Poitevin, RG Sierra, C Gati, E Han, YR Dao, F Aksit, H Ciftci, ...
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Artikler 1–20