| Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections JN Mandl, AP Barry, TH Vanderford, N Kozyr, R Chavan, S Klucking, ... Nature medicine 14 (10), 1077-1087, 2008 | 457 | 2008 |
| T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens JN Mandl, JP Monteiro, N Vrisekoop, RN Germain Immunity 38 (2), 263-274, 2013 | 366 | 2013 |
| Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naive CD4+ and CD8+ T cells JN Mandl, R Liou, F Klauschen, N Vrisekoop, JP Monteiro, AJ Yates, ... Proceedings of the National Academy of Sciences 109 (44), 18036-18041, 2012 | 202 | 2012 |
| DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity Q Zhang, CG Dove, JL Hor, HM Murdock, DM Strauss-Albee, JA Garcia, ... Journal of Experimental Medicine 211 (13), 2549-2566, 2014 | 182 | 2014 |
| Reservoir host immune responses to emerging zoonotic viruses JN Mandl, R Ahmed, LB Barreiro, P Daszak, JH Epstein, HW Virgin, ... Cell 160 (1), 20-35, 2015 | 175 | 2015 |
| Pathology in euthermic bats with white nose syndrome suggests a natural manifestation of immune reconstitution inflammatory syndrome CU Meteyer, D Barber, JN Mandl Virulence 3 (7), 583-588, 2012 | 151 | 2012 |
| The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus R Dunham, P Pagliardini, S Gordon, B Sumpter, J Engram, A Moanna, ... Blood 108 (1), 209-217, 2006 | 151 | 2006 |
| Going to bat (s) for studies of disease tolerance JN Mandl, C Schneider, DS Schneider, ML Baker Frontiers in Immunology 9, 2112, 2018 | 121 | 2018 |
| Revisiting thymic positive selection and the mature T cell repertoire for antigen N Vrisekoop, JP Monteiro, JN Mandl, RN Germain Immunity 41 (2), 181-190, 2014 | 107 | 2014 |
| Understanding the transmission dynamics of respiratory syncytial virus using multiple time series and nested models LJ White, JN Mandl, MGM Gomes, AT Bodley-Tickell, PA Cane, ... Mathematical biosciences 209 (1), 222-239, 2007 | 106 | 2007 |
| IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity C Lippens, FV Duraes, J Dubrot, D Brighouse, M Lacroix, M Irla, ... Journal of autoimmunity 75, 39-49, 2016 | 75 | 2016 |
| Random migration and signal integration promote rapid and robust T cell recruitment J Textor, SE Henrickson, JN Mandl, UH Von Andrian, J Westermann, ... PLoS computational biology 10 (8), e1003752, 2014 | 58 | 2014 |
| Estimating the Effectiveness of Simian Immunodeficiency Virus-Specific CD8+ T Cells from the Dynamics of Viral Immune Escape JN Mandl, RR Regoes, DA Garber, MB Feinberg Journal of virology 81 (21), 11982-11991, 2007 | 52 | 2007 |
| The race for the prize: T-cell trafficking strategies for optimal surveillance M Lee, JN Mandl, RN Germain, AJ Yates Blood, The Journal of the American Society of Hematology 120 (7), 1432-1438, 2012 | 49 | 2012 |
| CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection KE Yuki, H Marei, E Fiskin, MM Eva, AA Gopal, JA Schwartzentruber, ... Nature microbiology 4 (9), 1516-1531, 2019 | 47 | 2019 |
| Distinctive TLR7 signaling, type I IFN production, and attenuated innate and adaptive immune responses to yellow fever virus in a primate reservoir host JN Mandl, R Akondy, B Lawson, N Kozyr, SI Staprans, R Ahmed, ... The Journal of Immunology 186 (11), 6406-6416, 2011 | 46 | 2011 |
| Alterations in the thymic selection threshold skew the self-reactivity of the TCR repertoire in neonates M Dong, P Artusa, SA Kelly, M Fournier, TA Baldwin, JN Mandl, ... The Journal of Immunology 199 (3), 965-973, 2017 | 43 | 2017 |
| Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential D Rogers, A Sood, HC Wang, JJP van Beek, TJ Rademaker, P Artusa, ... Cell Reports 37 (9), 2021 | 37 | 2021 |
| Migration-induced cell shattering due to DOCK8 deficiency causes a type 2–biased helper T cell response C Schneider, C Shen, AA Gopal, T Douglas, B Forestell, KD Kauffman, ... Nature immunology 21 (12), 1528-1539, 2020 | 34 | 2020 |
| NK cell recruitment limits tissue damage during an enteric helminth infection ME Gentile, Y Li, A Robertson, K Shah, G Fontes, E Kaufmann, B Polese, ... Mucosal immunology 13 (2), 357-370, 2020 | 32 | 2020 |
Nienke VrisekoopAssistant Professor, Laboratory of Translational Immunology, UMCUVerificeret mail på umcutrecht.nl