Primary age-related tauopathy (PART): a common pathology associated with human aging JF Crary, JQ Trojanowski, JA Schneider, JF Abisambra, EL Abner, ... Acta neuropathologica 128, 755-766, 2014 | 1469 | 2014 |
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models MV Lourenco, RL Frozza, GB de Freitas, H Zhang, GC Kincheski, ... Nature medicine 25 (1), 165-175, 2019 | 819 | 2019 |
Interaction of tau with the RNA-binding protein TIA1 regulates tau pathophysiology and toxicity T Vanderweyde, DJ Apicco, K Youmans-Kidder, PEA Ash, C Cook, ... Cell reports 15 (7), 1455-1466, 2016 | 317 | 2016 |
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ... Journal of Neuroscience 33 (22), 9498-9507, 2013 | 281 | 2013 |
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ... Journal of Neuroscience 30 (2), 591-599, 2010 | 241 | 2010 |
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ... Molecular neurodegeneration 5, 1-11, 2010 | 208 | 2010 |
Pathological tau promotes neuronal damage by impairing ribosomal function and decreasing protein synthesis S Meier, M Bell, DN Lyons, J Rodriguez-Rivera, A Ingram, SN Fontaine, ... Journal of Neuroscience 36 (3), 1001-1007, 2016 | 175 | 2016 |
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ... Journal of Neuroscience 30 (46), 15374-15382, 2010 | 138 | 2010 |
RNA binding proteins co-localize with small tau inclusions in tauopathy BF Maziuk, DJ Apicco, AL Cruz, L Jiang, PEA Ash, EL da Rocha, C Zhang, ... Acta neuropathologica communications 6, 1-14, 2018 | 135 | 2018 |
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau J Abisambra, UK Jinwal, Y Miyata, J Rogers, L Blair, X Li, SP Seguin, ... Biological psychiatry 74 (5), 367-374, 2013 | 132 | 2013 |
Imbalance of Hsp70 family variants fosters tau accumulation UK Jinwal, E Akoury, JF Abisambra, JC O'Leary III, AD Thompson, LJ Blair, ... The FASEB Journal 27 (4), 1450, 2013 | 130 | 2013 |
Cerebral microvascular accumulation of tau oligomers in Alzheimer’s disease and related tauopathies DL Castillo-Carranza, AN Nilson, CE Van Skike, JB Jahrling, K Patel, ... Aging and disease 8 (3), 257, 2017 | 114 | 2017 |
Hsc70 rapidly engages tau after microtubule destabilization UK Jinwal, JC O'Leary, SI Borysov, JR Jones, Q Li, J Koren, JF Abisambra, ... Journal of biological chemistry 285 (22), 16798-16805, 2010 | 106 | 2010 |
Tau drives translational selectivity by interacting with ribosomal proteins SA Koren, MJ Hamm, SE Meier, BE Weiss, GK Nation, EA Chishti, ... Acta neuropathologica 137, 571-583, 2019 | 102 | 2019 |
Facilitating Akt clearance via manipulation of Hsp70 activity and levels J Koren, UK Jinwal, Y Jin, J O’Leary, JR Jones, AG Johnson, LJ Blair, ... Journal of biological chemistry 285 (4), 2498-2505, 2010 | 100 | 2010 |
PERK-opathies: an endoplasmic reticulum stress mechanism underlying neurodegeneration M C Bell, S E Meier, A L Ingram, J F Abisambra Current Alzheimer Research 13 (2), 150-163, 2016 | 90 | 2016 |
The Diarylheptanoid (+)-aR,11S-Myricanol and Two Flavones from Bayberry (Myrica cerifera) Destabilize the Microtubule-Associated Protein Tau JR Jones, MD Lebar, UK Jinwal, JF Abisambra, J Koren III, L Blair, ... Journal of natural products 74 (1), 38-44, 2011 | 90 | 2011 |
The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics UK Jinwal, JH Trotter, JF Abisambra, J Koren, LY Lawson, GD Vestal, ... Journal of Biological Chemistry 286 (19), 16976-16983, 2011 | 85 | 2011 |
Cdc37/Hsp90 protein complex disruption triggers an autophagic clearance cascade for TDP-43 protein UK Jinwal, JF Abisambra, J Zhang, S Dharia, JC O'Leary, T Patel, ... Journal of Biological Chemistry 287 (29), 24814-24820, 2012 | 79 | 2012 |
Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism A Suntharalingam, JF Abisambra, JC O'Leary III, J Koren III, B Zhang, ... Journal of Biological Chemistry 287 (48), 40661-40669, 2012 | 78 | 2012 |