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Julia TCW
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APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
A Montagne, DA Nation, AP Sagare, G Barisano, MD Sweeney, ...
Nature 581 (7806), 71-76, 2020
10452020
A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog
JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ...
Cell stem cell 5 (5), 491-503, 2009
9732009
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ...
Nature medicine 22 (10), 1101-1107, 2016
7192016
An efficient platform for astrocyte differentiation from human induced pluripotent stem cells
TCW Julia, M Wang, AA Pimenova, KR Bowles, BJ Hartley, E Lacin, ...
Stem cell reports 9 (2), 600-614, 2017
4262017
The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease
JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, ...
Nature 586 (7831), 735-740, 2020
3182020
Genetics of β-amyloid precursor protein in Alzheimer's disease
TCW Julia, AM Goate
Cold Spring Harbor perspectives in medicine 7 (6), a024539, 2017
2432017
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
TCW Julia, L Qian, NH Pipalia, MJ Chao, SA Liang, Y Shi, BR Jain, ...
Cell 185 (13), 2213-2233. e25, 2022
2422022
Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets
RA Neff, M Wang, S Vatansever, L Guo, C Ming, Q Wang, E Wang, ...
Science advances 7 (2), eabb5398, 2021
2172021
Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes
G Novikova, M Kapoor, J Tcw, EM Abud, AG Efthymiou, SX Chen, ...
Nature communications 12 (1), 1610, 2021
1902021
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells
SM Ho, BJ Hartley, TCW Julia, M Beaumont, K Stafford, PA Slesinger, ...
Methods 101, 113-124, 2016
1782016
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain
Y Jiang, YHE Loh, P Rajarajan, T Hirayama, W Liao, BS Kassim, ...
Nature genetics 49 (8), 1239-1250, 2017
1622017
Genetic architecture of Alzheimer's disease
SM Neuner, TCW Julia, AM Goate
Neurobiology of disease 143, 104976, 2020
1152020
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
K Leng, IVL Rose, H Kim, W Xia, W Romero-Fernandez, B Rooney, ...
Nature neuroscience 25 (11), 1528-1542, 2022
942022
Construction of a large synthetic human scFv library with six diversified CDRs and high functional diversity
HY Yang, KJ Kang, JE Chung, H Shim
Molecules and cells 27, 225-235, 2009
922009
Notch inhibition allows oncogene-independent generation of iPS cells
JK Ichida, J Tcw, LA Williams, AC Carter, Y Shi, MT Moura, M Ziller, ...
Nature chemical biology 10 (8), 632-639, 2014
752014
MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer’s disease pathogenesis
J Cao, M Huang, L Guo, L Zhu, J Hou, L Zhang, A Pero, S Ng, ...
Molecular psychiatry 26 (9), 4687-4701, 2021
602021
Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation
SR Saroja, K Gorbachev, J TCW, AM Goate, AC Pereira
Proceedings of the National Academy of Sciences 119 (34), e2108870119, 2022
502022
Reduced variability of neural progenitor cells and improved purity of neuronal cultures using magnetic activated cell sorting
KR Bowles, J Tcw, L Qian, BM Jadow, AM Goate
PloS one 14 (3), e0213374, 2019
502019
Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques
P Preman, J Tcw, S Calafate, A Snellinx, M Alfonso-Triguero, N Corthout, ...
Molecular neurodegeneration 16, 1-18, 2021
492021
Human iPSC application in Alzheimer’s disease and Tau-related neurodegenerative diseases
T Julia
Neuroscience letters 699, 31-40, 2019
492019
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