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Jun-An Chen
Jun-An Chen
Research Fellow. Academia Sinica
Verificeret mail på gate.sinica.edu.tw - Startside
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Mir-17-3p controls spinal neural progenitor patterning by regulating Olig2/Irx3 cross-repressive loop
JA Chen, YP Huang, EO Mazzoni, GC Tan, J Zavadil, H Wichterle
Neuron 69 (4), 721-735, 2011
1262011
An Lmx1b-miR135a2 Regulatory Circuit Modulates Wnt1/Wnt Signaling and Determines the Size of the Midbrain Dopaminergic Progenitor Pool
A Anderegg, HP Lin, JA Chen, G Caronia-Brown, N Cherepanova, B Yun, ...
PLoS genetics 9 (12), e1003973, 2013
692013
The m6A epitranscriptome on neural development and degeneration
YP Yen, JA Chen
Journal of biomedical science 28 (1), 40, 2021
642021
Mir-17∼ 92 confers motor neuron subtype differential resistance to ALS-associated degeneration
YT Tung, KC Peng, YC Chen, YP Yen, M Chang, S Thams, JA Chen
Cell Stem Cell 25 (2), 193-209. e7, 2019
492019
Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity
YP Yen, WF Hsieh, YY Tsai, YL Lu, ES Liau, HC Hsu, YC Chen, TC Liu, ...
Elife 7, e38080, 2018
452018
Functional roles of long non-coding RNAs in motor neuron development and disease
KW Chen, JA Chen
Journal of Biomedical Science 27 (1), 38, 2020
382020
Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional screen in Xenopus
JA Chen, J Voigt, M Gilchrist, N Papalopulu, E Amaya
Mechanisms of development 122 (3), 307-331, 2005
382005
Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific dicer inactivation
JA Chen, H Wichterle
Frontiers in neuroscience 6, 69, 2012
372012
MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
CJ Li, T Hong, YT Tung, YP Yen, HC Hsu, YL Lu, M Chang, Q Nie, ...
Nature Communications 8 (1), 14685, 2017
352017
Expression cloning screening of a unique and full-length set of cDNA clones is an efficient method for identifying genes involved in Xenopus neurogenesis
J Voigt, JA Chen, M Gilchrist, E Amaya, N Papalopulu
Mechanisms of development 122 (3), 289-306, 2005
342005
Multifaceted roles of microRNAs: From motor neuron generation in embryos to degeneration in spinal muscular atrophy
TH Chen, JA Chen
Elife 8, e50848, 2019
312019
Mir-17∼ 92 governs motor neuron subtype survival by mediating nuclear PTEN
YT Tung, YL Lu, KC Peng, YP Yen, M Chang, J Li, H Jung, S Thams, ...
Cell reports 11 (8), 1305-1318, 2015
312015
MicroRNA governs bistable cell differentiation and lineage segregation via a noncanonical feedback
CJ Li, ES Liau, YH Lee, YZ Huang, Z Liu, A Willems, V Garside, E McGlinn, ...
Molecular Systems Biology 17 (4), e9945, 2021
272021
Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons
ES Liau, S Jin, YC Chen, WS Liu, M Calon, S Nedelec, Q Nie, JA Chen
Nature Communications 14 (1), 46, 2023
242023
Inducible lncRNA transgenic mice reveal continual role of HOTAIR in promoting breast cancer metastasis
Q Ma, L Yang, K Tolentino, G Wang, Y Zhao, UM Litzenburger, Q Shi, ...
Elife 11, e79126, 2022
202022
Maintenance of motor neuron progenitors in Xenopus requires a novel localized cyclin
JA Chen, ST Chu, E Amaya
EMBO reports 8 (3), 287-292, 2007
112007
Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons. Nat. Commun. 14, 46
ES Liau, S Jin, YC Chen, WS Liu, M Calon, S Nedelec, Q Nie, JA Chen
doi. org/10.1038/s41467-022-35574-x, 2023
92023
MicroRNAs mediate precise control of spinal interneuron populations to exert delicate sensory-to-motor outputs
SH Chang, YC Su, M Chang, JA Chen
Elife 10, e63768, 2021
92021
MiR34 contributes to spinal muscular atrophy and AAV9-mediated delivery of MiR34a ameliorates the motor deficits in SMA mice
TH Chen, SH Chang, YF Wu, YP Yen, FY Hsu, YC Chen, Y Ming, HC Hsu, ...
Molecular Therapy-Nucleic Acids 32, 144-160, 2023
82023
Canonical mRNA is the exception, rather than the rule
JA Chen, S Conn
Genome Biology 18, 1-4, 2017
82017
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Artikler 1–20