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Pawel Zawadzki
Pawel Zawadzki
Poznan University, Poland/Gordion Bio, Cambridge MA
Verificeret mail på amu.edu.pl - Startside
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Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
Science immunology 6 (62), eabl4340, 2021
5362021
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19
T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ...
Science immunology 6 (62), eabl4348, 2021
3852021
A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection
JL Casanova, HC Su, L Abel, A Aiuti, S Almuhsen, AA Arias, P Bastard, ...
Cell 181 (6), 1194-1199, 2020
2742020
Live-cell superresolution microscopy reveals the organization of RNA polymerase in the bacterial nucleoid
M Stracy, C Lesterlin, F Garza de Leon, S Uphoff, P Zawadzki, ...
Proceedings of the National Academy of Sciences 112 (32), E4390-E4399, 2015
2712015
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ...
Proceedings of the National Academy of Sciences 119 (21), 2022
1672022
The localization and action of topoisomerase IV in Escherichia coli chromosome segregation is coordinated by the SMC complex, MukBEF
P Zawadzki, M Stracy, K Ginda, K Zawadzka, C Lesterlin, AN Kapanidis, ...
Cell reports 13 (11), 2587-2596, 2015
1192015
Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
M Stracy, M Jaciuk, S Uphoff, AN Kapanidis, M Nowotny, DJ Sherratt, ...
Nature communications 7 (1), 12568, 2016
1162016
Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
Q Zhang, D Matuozzo, J Le Pen, D Lee, L Moens, T Asano, J Bohlen, ...
Journal of Experimental Medicine 219 (8), 2022
1102022
RNA polymerase pausing during initial transcription
D Duchi, DLV Bauer, L Fernandez, G Evans, N Robb, LC Hwang, K Gryte, ...
Molecular cell 63 (6), 939-950, 2016
992016
Single-molecule imaging of DNA gyrase activity in living Escherichia coli
M Stracy, AJM Wollman, E Kaja, J Gapinski, JE Lee, VA Leek, SJ McKie, ...
Nucleic acids research 47 (1), 210-220, 2019
942019
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
D Matuozzo, E Talouarn, A Marchal, P Zhang, J Manry, Y Seeleuthner, ...
Genome medicine 15 (1), 22, 2023
632023
MukB ATPases are regulated independently by the N-and C-terminal domains of MukF kleisin
K Zawadzka, P Zawadzki, R Baker, KV Rajasekar, F Wagner, DJ Sherratt, ...
Elife 7, e31522, 2018
602018
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways
HL Klein, G Bačinskaja, J Che, A Cheblal, R Elango, A Epshtein, ...
Microbial cell 6 (1), 1, 2019
582019
Capturing reaction paths and intermediates in Cre-loxP recombination using single-molecule fluorescence
JNM Pinkney, P Zawadzki, J Mazuryk, LK Arciszewska, DJ Sherratt, ...
Proceedings of the National Academy of Sciences 109 (51), 20871-20876, 2012
572012
Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative
G Butler-Laporte, G Povysil, JA Kosmicki, ET Cirulli, T Drivas, S Furini, ...
PLoS genetics 18 (11), e1010367, 2022
442022
Conformational transitions during FtsK translocase activation of individual XerCD–dif recombination complexes
P Zawadzki, PFJ May, RA Baker, JNM Pinkney, AN Kapanidis, DJ Sherratt, ...
Proceedings of the National Academy of Sciences 110 (43), 17302-17307, 2013
352013
The Thousand Polish Genomes—a database of Polish variant allele frequencies
E Kaja, A Lejman, D Sielski, M Sypniewski, T Gambin, M Dawidziuk, ...
International Journal of Molecular Sciences 23 (9), 4532, 2022
282022
Tethered fluorophore motion: studying large DNA conformational changes by single-fluorophore imaging
PFJ May, JNM Pinkney, P Zawadzki, GW Evans, DJ Sherratt, ...
Biophysical Journal 107 (5), 1205-1216, 2014
272014
Assembly, translocation, and activation of XerCD-dif recombination by FtsK translocase analyzed in real-time by FRET and two-color tethered fluorophore motion
PFJ May, P Zawadzki, DJ Sherratt, AN Kapanidis, LK Arciszewska
Proceedings of the National Academy of Sciences 112 (37), E5133-E5141, 2015
212015
A Fluorescence Correlation Spectroscopy Study of Ligand Interaction with Cytokinin-Specific Binding Protein from Mung Bean
WP Zawadzki Pawel, Ślósarek Genowefa, Boryski Jerzy
Biological Chemistry, 43–53, 2010
21*2010
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Artikler 1–20