Telomere shortening and tumor formation by mouse cells lacking telomerase RNA MA Blasco, HW Lee, MP Hande, E Samper, PM Lansdorp, RA DePinho, ... Cell 91 (1), 25-34, 1997 | 2731 | 1997 |
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53 J Pomerantz, N Schreiber-Agus, NJ Liégeois, A Silverman, L Alland, ... Cell 92 (6), 713-723, 1998 | 2025 | 1998 |
Role of the INK4a locus in tumor suppression and cell mortality M Serrano, HW Lee, L Chin, C Cordon-Cardo, D Beach, RA DePinho Cell 85 (1), 27-37, 1996 | 1978 | 1996 |
Differential antigen processing by dendritic cell subsets in vivo D Dudziak, AO Kamphorst, GF Heidkamp, VR Buchholz, C Trumpfheller, ... Science 315 (5808), 107-111, 2007 | 1764 | 2007 |
Longevity, stress response, and cancer in aging telomerase-deficient mice KL Rudolph, S Chang, HW Lee, M Blasco, GJ Gottlieb, C Greider, ... Cell 96 (5), 701-712, 1999 | 1661 | 1999 |
Essential role of mouse telomerase in highly proliferative organs HW Lee, MA Blasco, GJ Gottlieb, JW Horner, CW Greider, RA DePinho Nature 392 (6676), 569-574, 1998 | 1577 | 1998 |
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres E Herrera, E Samper, J Martín‐Caballero, JM Flores, HW Lee, MA Blasco The EMBO journal, 1999 | 590 | 1999 |
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation AR Choudhury, Z Ju, MW Djojosubroto, A Schienke, A Lechel, ... Nature genetics 39 (1), 99-105, 2007 | 518 | 2007 |
Knockout mice created by TALEN-mediated gene targeting YH Sung, IJ Baek, DH Kim, J Jeon, J Lee, K Lee, D Jeong, JS Kim, ... Nature biotechnology 31 (1), 23-24, 2013 | 438 | 2013 |
Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production GH Son, S Chung, HK Choe, HD Kim, SM Baik, H Lee, HW Lee, S Choi, ... Proceedings of the National Academy of Sciences 105 (52), 20970-20975, 2008 | 375 | 2008 |
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases YH Sung, JM Kim, HT Kim, J Lee, J Jeon, Y Jin, JH Choi, YH Ban, SJ Ha, ... Genome research 24 (1), 125-131, 2014 | 335 | 2014 |
Rapid induction of senescence in human cervical carcinoma cells EC Goodwin, E Yang, CJ Lee, HW Lee, D DiMaio, ES Hwang Proceedings of the National Academy of Sciences 97 (20), 10978-10983, 2000 | 261 | 2000 |
Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth N Schreiber-Agus, Y Meng, T Hoang, H Hou Jr, K Chen, R Greenberg, ... Nature 393 (6684), 483-487, 1998 | 244 | 1998 |
Srg3, a mouse homolog of yeast SWI3, is essential for early embryogenesis and involved in brain development JK Kim, SO Huh, H Choi, KS Lee, D Shin, C Lee, JS Nam, H Kim, ... Molecular and cellular biology 21 (22), 7787-7795, 2001 | 231 | 2001 |
Telomeres and telomerase in aging, regeneration and cancer MW Djojosubroto, YS Choi, HW Lee, KL Rudolph Molecules and cells 15 (2), 164-175, 2003 | 226 | 2003 |
Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation MJ Kim, BJ Park, YS Kang, HJ Kim, JH Park, JW Kang, SW Lee, JM Han, ... Nature genetics 34 (3), 330-336, 2003 | 211 | 2003 |
Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity HJ Kang, YS Choi, SB Hong, KW Kim, RS Woo, SJ Won, EJ Kim, HK Jeon, ... Journal of Neuroscience 24 (6), 1280-1287, 2004 | 191 | 2004 |
TERT promotes cellular and organismal survival independently of telomerase activity J Lee, YH Sung, C Cheong, YS Choi, HK Jeon, W Sun, WC Hahn, ... Oncogene 27 (26), 3754-3760, 2008 | 188 | 2008 |
Animal Model for Maturity-onset Diabetes of the Young Generated by Disruption of the Mouse Glucokinase Gene (∗) D Bali, A Svetlanov, HW Lee, D Fusco-DeMane, M Leiser, B Li, N Barzilai, ... Journal of Biological Chemistry 270 (37), 21464-21467, 1995 | 179 | 1995 |
p19Arf induces p53-dependent apoptosis during Abelson virus-mediated pre-B cell transformation A Radfar, I Unnikrishnan, HW Lee, RA DePinho, N Rosenberg Proceedings of the National Academy of Sciences 95 (22), 13194-13199, 1998 | 175 | 1998 |