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Bruno Pagano
Bruno Pagano
Department of Pharmacy, University of Naples Federico II
Verificeret mail på unina.it
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Shedding light on the interaction between TMPyP4 and human telomeric quadruplexes
L Martino, B Pagano, I Fotticchia, S Neidle, C Giancola
The Journal of Physical Chemistry B 113 (44), 14779-14786, 2009
1962009
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4
L Martino, A Virno, B Pagano, A Virgilio, S Di Micco, A Galeone, ...
Journal of the American Chemical Society 129 (51), 16048-16056, 2007
1942007
Structural revision of clusianone and 7-epi-clusianone and anti-HIV activity of polyisoprenylated benzophenones
AL Piccinelli, O Cuesta-Rubio, MB Chica, N Mahmood, B Pagano, ...
Tetrahedron 61 (34), 8206-8211, 2005
1932005
Stability and binding properties of a modified thrombin binding aptamer
B Pagano, L Martino, A Randazzo, C Giancola
Biophysical Journal 94 (2), 562-569, 2008
1782008
The G‐Triplex DNA
V Limongelli, S De Tito, L Cerofolini, M Fragai, B Pagano, R Trotta, ...
Angewandte Chemie International Edition 52 (8), 2269-2273, 2013
1712013
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations
F Moraca, J Amato, F Ortuso, A Artese, B Pagano, E Novellino, S Alcaro, ...
Proceedings of the National Academy of Sciences 114 (11), E2136-E2145, 2017
1242017
Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle
S Cosconati, L Marinelli, R Trotta, A Virno, S De Tito, R Romagnoli, ...
Journal of the American Chemical Society 132 (18), 6425-6433, 2010
1222010
Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes
B Pagano, CA Mattia, C Giancola
International Journal of Molecular Sciences 10 (7), 2935-2957, 2009
1042009
Common G-quadruplex binding agents found to interact with i-motif-forming DNA: Unexpected multi-target-directed compounds
A Pagano, N Iaccarino, MAS Abdelhamid, D Brancaccio, EU Garzarella, ...
Frontiers in Chemistry 6, 281, 2018
842018
Toward the development of specific G-quadruplex binders: Synthesis, biophysical, and biological studies of new hydrazone derivatives
J Amato, R Morigi, B Pagano, A Pagano, S Ohnmacht, A De Magis, ...
Journal of Medicinal Chemistry 59 (12), 5706-5720, 2016
692016
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein
J Amato, L Cerofolini, D Brancaccio, S Giuntini, N Iaccarino, P Zizza, ...
Nucleic acids research 47 (18), 9950-9966, 2019
622019
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death
S Cosconati, A Rizzo, R Trotta, B Pagano, S Iachettini, S De Tito, I Lauri, ...
Journal of Medicinal Chemistry 55 (22), 9785-9792, 2012
622012
Looking for efficient G‐quadruplex ligands: evidence for selective stabilizing properties and telomere damage by drug‐like molecules
B Pagano, J Amato, N Iaccarino, C Cingolani, P Zizza, A Biroccio, ...
ChemMedChem 10 (4), 640-649, 2015
612015
State-of-the-Art Methodologies for the Discovery and Characterization of DNA G-Quadruplex Binders.
B Pagano, S Cosconati, V Gabelica, L Petraccone, S De Tito, L Marinelli, ...
Current Pharmaceutical Design 18 (14), 1880-1899, 2012
612012
Targeting G-Quadruplex Structure in the Human c-Kit Promoter with Short PNA Sequences
J Amato, B Pagano, N Borbone, G Oliviero, V Gabelica, ED Pauw, ...
Bioconjugate Chemistry 22 (4), 654-663, 2011
612011
Targeting DNA quadruplexes with distamycin A and its derivatives: an ITC and NMR study
B Pagano, A Virno, CA Mattia, L Mayol, A Randazzo, C Giancola
Biochimie 90 (8), 1224-1232, 2008
612008
Structure of a stable G-hairpin
M Gajarský, ML Zivkovic, P Stadlbauer, B Pagano, R Fiala, J Amato, ...
Journal of the American Chemical Society 139 (10), 3591-3594, 2017
602017
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis
E Salvati, P Zizza, A Rizzo, S Iachettini, C Cingolani, C D’Angelo, M Porru, ...
Nucleic Acids Research 42 (5), 2945-2957, 2014
602014
Thermodynamics and Kinetics of PNA− DNA Quadruplex-Forming Chimeras
L Petraccone, B Pagano, V Esposito, A Randazzo, G Piccialli, G Barone, ...
Journal of the American Chemical Society 127 (46), 16215-16223, 2005
592005
HMGB1 binds to the KRAS promoter G-quadruplex: a new player in oncogene transcriptional regulation?
J Amato, TW Madanayake, N Iaccarino, E Novellino, A Randazzo, ...
Chemical Communications 54 (68), 9442-9445, 2018
572018
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Artikler 1–20