cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth Z Chen, JL Li, S Lin, C Cao, NT Gimbrone, R Yang, DA Fu, MB Carper, ... The Journal of clinical investigation 126 (6), 2267-2279, 2016 | 209 | 2016 |
DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia S Lin, L Tian, H Shen, Y Gu, JL Li, Z Chen, X Sun, M James You, L Wu Oncogene 32 (40), 4845-4853, 2013 | 105 | 2013 |
Recent insights into the biological activities and drug delivery systems of tanshinones Y Cai, W Zhang, Z Chen, Z Shi, C He, M Chen International Journal of Nanomedicine, 121-130, 2016 | 103 | 2016 |
Aberrantly activated AREG–EGFR signaling is required for the growth and survival of CRTC1–MAML2 fusion-positive mucoepidermoid carcinoma cells Z Chen, J Chen, Y Gu, C Hu, JL Li, S Lin, H Shen, C Cao, R Gao, J Li, ... Oncogene 33 (29), 3869-3877, 2014 | 99 | 2014 |
Altered LKB1/CREB-regulated transcription co-activator (CRTC) signaling axis promotes esophageal cancer cell migration and invasion Y Gu, S Lin, JL Li, H Nakagawa, Z Chen, B Jin, L Tian, DA Ucar, H Shen, ... Oncogene 31 (4), 469-479, 2012 | 91 | 2012 |
A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets R Gao, C Cao, M Zhang, MC Lopez, Y Yan, Z Chen, Y Mitani, L Zhang, ... Oncotarget 5 (24), 12528, 2014 | 59 | 2014 |
The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma Z Chen, W Ni, JL Li, S Lin, X Zhou, Y Sun, JW Li, ME Leon, MD Hurtado, ... JCI insight 6 (7), e139497, 2021 | 53 | 2021 |
CRTC1-MAML2 fusion-induced lncRNA LINC00473 expression maintains the growth and survival of human mucoepidermoid carcinoma cells Z Chen, S Lin, JL Li, W Ni, R Guo, J Lu, FJ Kaye, L Wu Oncogene 37 (14), 1885-1895, 2018 | 52 | 2018 |
Brief report: Blockade of Notch signaling in muscle stem cells causes muscular dystrophic phenotype and impaired muscle regeneration S Lin, H Shen, B Jin, Y Gu, Z Chen, C Cao, C Hu, C Keller, WS Pear, L Wu Stem Cells 31 (4), 823-828, 2013 | 51 | 2013 |
Role of LKB1-CRTC1 on glycosylated COX-2 and response to COX-2 inhibition in lung cancer C Cao, R Gao, M Zhang, AL Amelio, M Fallahi, Z Chen, Y Gu, C Hu, ... Journal of the National Cancer Institute 107 (1), dju358, 2015 | 47 | 2015 |
The mastermind-like 1 (MAML1) co-activator regulates constitutive NF-κB signaling and cell survival B Jin, H Shen, S Lin, JL Li, Z Chen, JD Griffin, L Wu Journal of Biological Chemistry 285 (19), 14356-14365, 2010 | 45 | 2010 |
Proteomic and Functional Analyses Reveal the Role of Chromatin Reader SFMBT1 in Regulating Epigenetic Silencing and the Myogenic Gene Program*[S] S Lin, H Shen, JL Li, S Tang, Y Gu, Z Chen, C Hu, JC Rice, J Lu, L Wu Journal of Biological Chemistry 288 (9), 6238-6247, 2013 | 40 | 2013 |
Gene expression profiling analysis of CRTC1-MAML2 fusion oncogene-induced transcriptional program in human mucoepidermoid carcinoma cells J Chen, JL Li, Z Chen, JD Griffin, L Wu BMC cancer 15, 1-13, 2015 | 38 | 2015 |
Role of INSL4 signaling in sustaining the growth and viability of LKB1-inactivated lung cancer R Yang, SW Li, Z Chen, X Zhou, W Ni, DA Fu, J Lu, FJ Kaye, L Wu JNCI: Journal of the National Cancer Institute 111 (7), 664-674, 2019 | 30 | 2019 |
Targeting Notch and EGFR signaling in human mucoepidermoid carcinoma W Ni, Z Chen, X Zhou, R Yang, M Yu, J Lu, FJ Kaye, L Wu Signal Transduction and Targeted Therapy 6 (1), 27, 2021 | 22 | 2021 |
Dependency of human and murine LKB1-inactivated lung cancer on aberrant CRTC-CREB activation X Zhou, JW Li, Z Chen, W Ni, X Li, R Yang, H Shen, J Liu, FJ DeMayo, ... Elife 10, e66095, 2021 | 13 | 2021 |
DNA methyltransferase inhibitor CDA-II inhibits myogenic differentiation Z Chen, G Jin, S Lin, X Lin, Y Gu, Y Zhu, C Hu, Q Zhang, L Wu, H Shen Biochemical and biophysical research communications 422 (3), 522-526, 2012 | 11 | 2012 |
Overexpression of Six1 leads to retardation of myogenic differentiation in C2C12 myoblasts Z Li, D Deng, H Huang, L Tian, Z Chen, Y Zou, G Jin, J Wang, Q Zhang, ... Molecular biology reports 40, 217-223, 2013 | 6 | 2013 |
ONM-501: A polyvalent STING agonist for oncology immunotherapy S Li, J Wang, J Wilhelm, Q Su, G Bharadwaj, J Miller, W Li, K Torres, ... Cancer Research 82 (12 Supplement), 4234, 2022 | 5 | 2022 |
Abstract LB245: ONM-501, a dual-activating polyvalent STING agonist, enhances tumor retention and demonstrates favorable preclinical safety profile Z Chen, G Huang, K Torres, F Stavros, A Ahmed, J Miller, T Zhao, J Gao, ... Cancer Research 83 (8_Supplement), LB245-LB245, 2023 | 2 | 2023 |