| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13753* | 2021 |
| Intratumor heterogeneity and branched evolution revealed by multiregion sequencing M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ... New England journal of medicine 366 (10), 883-892, 2012 | 8917 | 2012 |
| Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ... Science 351 (6280), 1463-1469, 2016 | 3194 | 2016 |
| Clonal heterogeneity and tumor evolution: past, present, and the future N McGranahan, C Swanton Cell 168 (4), 613-628, 2017 | 2732 | 2017 |
| The causes and consequences of genetic heterogeneity in cancer evolution RA Burrell, N McGranahan, J Bartek, C Swanton Nature 501 (7467), 338-345, 2013 | 2683 | 2013 |
| Renal cell carcinoma JJ Hsieh, MP Purdue, S Signoretti, C Swanton, L Albiges, M Schmidinger, ... Nature reviews Disease primers 3 (1), 1-19, 2017 | 2555 | 2017 |
| Tracking the evolution of non–small-cell lung cancer M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ... New England Journal of Medicine 376 (22), 2109-2121, 2017 | 2388 | 2017 |
| Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic TA Chan, M Yarchoan, E Jaffee, C Swanton, SA Quezada, A Stenzinger, ... Annals of Oncology 30 (1), 44-56, 2019 | 2315 | 2019 |
| Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ... Nature 545 (7655), 446-451, 2017 | 1867 | 2017 |
| Artificial intelligence in cancer imaging: clinical challenges and applications WL Bi, A Hosny, MB Schabath, ML Giger, NJ Birkbak, A Mehrtash, ... CA: a cancer journal for clinicians 69 (2), 127-157, 2019 | 1657 | 2019 |
| Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing M Gerlinger, S Horswell, J Larkin, AJ Rowan, MP Salm, I Varela, R Fisher, ... Nature genetics 46 (3), 225-233, 2014 | 1422 | 2014 |
| Chromosomal instability drives metastasis through a cytosolic DNA response SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ... Nature 553 (7689), 467-472, 2018 | 1391 | 2018 |
| Allele-specific HLA loss and immune escape in lung cancer evolution N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ... Cell 171 (6), 1259-1271. e11, 2017 | 1301 | 2017 |
| Spatial and temporal diversity in genomic instability processes defines lung cancer evolution EC De Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ... Science 346 (6206), 251-256, 2014 | 1289 | 2014 |
| Biological and therapeutic impact of intratumor heterogeneity in cancer evolution N McGranahan, C Swanton Cancer cell 27 (1), 15-26, 2015 | 1248 | 2015 |
| Cancer heterogeneity: implications for targeted therapeutics R Fisher, L Pusztai, C Swanton British journal of cancer 108 (3), 479-485, 2013 | 1246 | 2013 |
| Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA MC Liu, GR Oxnard, EA Klein, C Swanton, MV Seiden, MC Liu, ... Annals of Oncology 31 (6), 745-759, 2020 | 1177 | 2020 |
| Intratumor heterogeneity: evolution through space and time C Swanton Cancer research 72 (19), 4875-4882, 2012 | 1155 | 2012 |
| DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution R Rosenthal, N McGranahan, J Herrero, BS Taylor, C Swanton Genome biology 17, 1-11, 2016 | 1119 | 2016 |
| Genomic features of response to combination immunotherapy in patients with advanced non-small-cell lung cancer MD Hellmann, T Nathanson, H Rizvi, BC Creelan, F Sanchez-Vega, ... Cancer cell 33 (5), 843-852. e4, 2018 | 1003 | 2018 |
Nicholas McGranahanGroup Leader, CRUK Lung Cancer Centre of Excellence, UCL Cancer InstituteVerificeret mail på ucl.ac.uk